Výsledky vyhledávání - "Kenichiro Kinoshita"

Presence of antibodies to p21X and/or p27rex proteins in sera from human T-cell leukemia virus type I-infected individuals

Autor: Satoshi Orita, Kenichiro Kinoshita, Yuko Aono, Hisanaga Igarashi, Akihiko Saiga, Joko Imai

Publikováno v: Journal of Virological Methods. 57:157-168

The human T-cell leukemia virus type I (HTLV-I) pX gene encodes three nonstructural proteins, p40tax, p27rex and p21X. So far, natural antibodies to p27rex and/or p21X have not been found in sera from HTLV-I-infected individuals, although antibodies

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4668892c4fae593474f1c52029a4f601
https://doi.org/10.1016/0166-0934(95)01979-0

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Anti-Human T-Lymphotropic Virus Type-I Antibodies in Atomic-Bomb Survivors

Autor: Tatsuki Matsuo, Eiji Nakashima, Kenichiro Kinoshita, Michito Ichimaru, Kiyohiko Mabuchi, Masao Tomonaga, Mitoshi Akiyama, Katsutaro Shimaoka, Kazuo Neriishi, Randolph L. Carter

Publikováno v: Journal of radiation research. 36(1):8-16

Adult T-cell leukemia (ATL), induced by human T-lymphotropic virus type-I (HTLV-I), is endemic in Nagasaki, Japan. To investigate the effects of atomic-bomb radiation on development of this specific type of leukemia, 6182 individuals in the Radiation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9158fd3370d8cae6a5e1ecfdd705ea1e
https://nagasaki-u.repo.nii.ac.jp/records/19552

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Clinical course of human T-lymphotropic virus type I carriers with molecularly detectable monoclonal proliferation of T lymphocytes: defining a low- and high-risk population

Autor: T Kanda, S Ikeda, S Kamihira, Kunihiro Tsukasaki, Ryozo Moriuchi, Kenichiro Kinoshita, T Nakamura, Yukiyoshi Moriuchi, Saburo Momita, M Ito

Publikováno v: Blood. 82:2017-2024

To characterize the prodromal phase of adult T-cell leukemia (ATL), a prospective follow-up study was conducted on 50 carriers in a putative pre-ATL state. This state was defined by the presence of molecularly- detectable monoclonal proliferation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4c733345ffa0c03ad7cc08f5e9c403
https://doi.org/10.1182/blood.v82.7.2017.2017

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Human T cell leukaemia virus type 1 p21X mRNA: constitutive expression in peripheral blood mononuclear cells of patients with adult T cell leukaemia

Autor: Kenichiro Kinoshita, Akihiko Saiga, Shin Takagi, Naoko Minoura, Toshifumi Kondo, Yorio Hinuma, Hisanaga Igarashi, K. Araki, Satoshi Orita

Publikováno v: Journal of General Virology. 73:2283-2289

Although the p21X protein of human T cell leukaemia virus type 1 (HTLV-1) is generally thought to be expressed from a doubly spliced mRNA transcript (tax/rex mRNA) that encodes the p40tax, p27rex and p21X proteins, we have shown previously that a nov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb2bb2e9a186f3606b1b8c24683d0fe7
https://doi.org/10.1099/0022-1317-73-9-2283

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Frequency of eosinophilia in adult T-cell leukemia/lymphoma

Autor: Naoki Sadamori, Ken Murata, Saburo Momita, Sunao Atogami, Masao Tomonaga, Amagasaki T, Yasuaki Yamada, Kunihiro Tsukasaki, Shimeru Kamihira, Kenichiro Kinoshita, Michito Ichimaru

Publikováno v: Cancer. 69:966-971

Cases of adult T-cell leukemia/lymphoma (ATLL) display several peculiar clinical features, including skin rash, hypercalcemia, and an increase in the absolute neutrophil count. The patients rarely have pronounced eosinophilia. In this study, the eosi

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https://doi.org/10.1002/1097-0142(19920215)69:4<966::aid-cncr2820690422>3.0.co

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Prognostic significance of the proportion of Ki-67-positive cells in adult t-cell leukemia

Autor: Masuko Tagawa, Kenichiro Kinoshita, Hisashi Sohda, Toru Jubashi, Kazutaka Kuriyama, Saburo Momita, Ken Murata, Kunihiro Tsukasaki, Yukinobu Oyakawa, Amagasaki T, Yasuaki Yamada, Masao Tomonaga, Sunao Atogami, Takao Yanagisako, Shimeru Kamihira, Michito Ichimaru

Publikováno v: Cancer. 67:2605-2609

The authors examined peripheral blood samples from patients with adult T-cell leukemia (ATL) using the monoclonal antibody Ki-67 which detects a nuclear antigen present in actively proliferating cells. In patients with chronic ATL, the percentage of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::027d77dc6a6c87029286810dff912028
https://doi.org/10.1002/1097-0142(19910515)67:10<2605::aid-cncr2820671034>3.0.co

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Survey of Anti-human T-Cell Leukemia Virus Type I Antibody in Family Members of Patients with Adult T-Cell Leukemia

Autor: Kenichiro Kinoshita, Yasuaki Yamada, Shimeru Kamihira, Saburo Momita, Michito Ichimaru, Masao Tomonaga, Hisashi Soda, Shuichi Ikeda, Amagasaki T

Publikováno v: Japanese Journal of Cancer Research : Gann

To evaluate the intrafamilial clustering of HTLV-I, we examined the sera or plasma of 296 healthy family members of patients with adult T-cell leukemia (ATL) for anti-HTLV-I antibodies. Of 296 subjects, 132 (44.6%) had anti-HTLV-I antibodies. Fifty-n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a362660d58e185a6e33cddb9af5db967
https://doi.org/10.1111/j.1349-7006.1990.tb02662.x

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Serum Gc, Hp and α2HS Phenotypes in Human T-Lymphotropic Leukemia Virus Type I Infection

Autor: Michito Ichimaru, Kenichiro Kinoshita, Shuichi Ikeda, M. Iwasaki, Ogata M, Ichiro Nakasono, Shin-ichi Kubo, Saburo Momida, Hirofumi Suyama

Publikováno v: Human Heredity. 40:253-256

The serum Gc, Hp and α2HS phenotypes were examined in 64 subjects known to have the human T-lymphotropic leukemia virus type I (HTLV-I) infection and in 60 uninfected subjects. There were n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68961ced63f8c3d7d9a4b172dab70499
https://doi.org/10.1159/000153940

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An intensive chemotherapy of adult T-cell leukemia/lymphoma: CHOP followed by etoposide, vindesine, ranimustine, and mitoxantrone with granulocyte colony-stimulating factor support

Publikováno v: Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association. 12(2)

An intensive combination chemotherapy regimen supported by granulocyte colony-stimulating factor (G-CSF) was evaluated in adult T-cell leukemia/lymphoma (ATLL) patients in a multiinstitutional, cooperative study. Vincristine 1 mg/m2 i.v. day 1, Adria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4454304d1261913802ec40eaf66e1c27
https://pubmed.ncbi.nlm.nih.gov/8680890

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Cohort study of hepatotropic virus and human T lymphotropic virus type-I infections in an area endemic for adult T cell leukemia

Autor: Yasuaki Yamada, Sunao Atogami, Masao Tomonaga, Kenichiro Kinoshita, Shimeru Kamihira, Saburo Momita, Shuichi Ikeda, Ryuzi Furukawa, H Sohda, Kazuhiro Toriya

Publikováno v: Japanese journal of medicine. 30(6)

We tested for antibodies to hepatitis B virus (HBV), hepatitis C virus (HCV), and human T lymphotropic virus type-I (HTLV-I) in 629 normal inhabitants of an adult T cell leukemia (ATL) endemic area and in patients with ATL, HTLV-I associated myelopat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5747f2ae0a5632e672fc3e73b9bfda35
https://pubmed.ncbi.nlm.nih.gov/1665877

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