Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Kenichiro HATA"'
Autor:
Layla Masuda, Akihiro Hasegawa, Hiromi Kamura, Fuyuki Hasegawa, Michihiro Yamamura, Kosuke Taniguchi, Yuki Ito, Kenichiro Hata, Osamu Samura, Aikou Okamoto
Publikováno v:
Human Genome Variation, Vol 11, Iss 1, Pp 1-4 (2024)
Abstract Type 2 spinal muscular atrophy with lower extremity dominance (SMALED2) is caused by bicaudal D cargo adaptor 2 (BICD2) variants. However, the SMALED2 genotype and phenotype correlation have not been thoroughly characterized. We identified d
Externí odkaz:
https://doaj.org/article/f328667ec5474d7ab76dccc3d414bfa8
Autor:
Alexandra Lukyanchuk, Naomi Muraki, Tomoko Kawai, Takehiro Sato, Kenichiro Hata, Tsuyoshi Ito, Atsushi Tajima
Publikováno v:
Epigenetics & Chromatin, Vol 17, Iss 1, Pp 1-14 (2024)
Abstract Background Diesel exhaust particles (DEP), which contain hazardous compounds, are emitted during the combustion of diesel. As approximately one-third of the vehicles worldwide use diesel, there are growing concerns about the risks posed by D
Externí odkaz:
https://doaj.org/article/e0b06d2b624149b0a2deebcfa2688545
Autor:
Cecilia Rengifo Rojas, Jil Cercy, Sophie Perillous, Céline Gonthier-Guéret, Bertille Montibus, Stéphanie Maupetit-Méhouas, Astrid Espinadel, Marylou Dupré, Charles C. Hong, Kenichiro Hata, Kazuhiko Nakabayashi, Antonius Plagge, Tristan Bouschet, Philippe Arnaud, Isabelle Vaillant, Franck Court
Publikováno v:
HGG Advances, Vol 5, Iss 2, Pp 100271- (2024)
Summary: It is only partially understood how constitutive allelic methylation at imprinting control regions (ICRs) interacts with other regulation levels to drive timely parental allele-specific expression along large imprinted domains. The Peg13-Kcn
Externí odkaz:
https://doaj.org/article/d7cbd17169d146879f77c972bc9cd96b
Autor:
Keita Hasegawa, Kazuhiko Nakabayashi, Keisuke Ishiwata, Yoshifumi Kasuga, Kenichiro Hata, Mamoru Tanaka
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-6 (2023)
Abstract Objective The opportunities for sequencing-based methylome analysis of clinical samples are increasing. To reduce its cost and the amount of genomic DNA required for library preparation, we aimed to establish a capture methyl-seq protocol, w
Externí odkaz:
https://doaj.org/article/3d4eb7f99c8142a89e8228718c73f7a0
Autor:
Shiori Kinoshita, Kazuaki Kojima, Eriko Ohnishi, Yuka Takayama, Hiroki Kikuchi, Shuji Takada, Kazuhiko Nakabayashi, Tomoko Kawai, Kenichiro Hata
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background: Epigenetic disruptions have been implicated in neurodevelopmental disorders. NSD2 is associated with developmental delay/intellectual disability; however, its role in brain development and function remains unclear.Methods: We performed tr
Externí odkaz:
https://doaj.org/article/a55c640feebc490b8dbe57f06ebdad12
Autor:
Fumiya Takahashi, Takashi Baba, Antonius Christianto, Shogo Yanai, Hyeon-Cheol Lee-Okada, Keisuke Ishiwata, Kazuhiko Nakabayashi, Kenichiro Hata, Tomohiro Ishii, Tomonobu Hasegawa, Takehiko Yokomizo, Man Ho Choi, Ken-ichirou Morohashi
Publikováno v:
Cell Reports, Vol 43, Iss 2, Pp 113715- (2024)
Summary: The zona fasciculata (zF) in the adrenal cortex contributes to multiple physiological actions through glucocorticoid synthesis. The size, proliferation, and glucocorticoid synthesis characteristics are all female biased, and sexual dimorphis
Externí odkaz:
https://doaj.org/article/9961e1b280314f7cbbce9266e2036088
Autor:
Akiko Suga, Kei Mizobuchi, Taiga Inooka, Kazutoshi Yoshitake, Naoko Minematsu, Kazushige Tsunoda, Kazuki Kuniyoshi, Yosuke Kawai, Yosuke Omae, Katsushi Tokunaga, Takaaki Hayashi, Shinji Ueno, Takeshi Iwata, Hatsue Ishibashi-Ueda, Tsutomu Tomita, Michio Noguchi, Ayako Takahashi, Yu-ichi Goto, Sumiko Yoshida, Kotaro Hattori, Ryo Matsumura, Aritoshi Iida, Yutaka Maruoka, Hiroyuki Gatanaga, Masaya Sugiyama, Satoshi Suzuki, Kengo Miyo, Yoichi Matsubara, Akihiro Umezawa, Kenichiro Hata, Tadashi Kaname, Kouichi Ozaki, Haruhiko Tokuda, Hiroshi Watanabe, Shumpei Niida, Eisei Noiri, Koji Kitajima, Reiko Miyahara, Hideyuki Shimanuki
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101843- (2024)
Purpose: Achromatopsia (ACHM) is an early-onset cone dysfunction caused by 5 genes with cone-specific functions (CNGA3, CNGB3, GNAT2, PDE6C, and PDE6H) and by ATF6, a transcription factor with ubiquitous expression. To improve the relatively low vari
Externí odkaz:
https://doaj.org/article/a0a40200ace245f49c062e5cf42c6c3b
Autor:
Keita Hasegawa, Natsuhiko Kumasaka, Kazuhiko Nakabayashi, Hiromi Kamura, Kayoko Maehara, Yoshifumi Kasuga, Kenichiro Hata, Mamoru Tanaka
Publikováno v:
Human Genome Variation, Vol 10, Iss 1, Pp 1-4 (2023)
Abstract Preterm birth (PTB), defined as the birth of a baby at
Externí odkaz:
https://doaj.org/article/d19c0671a182427580b784dbdb8c4c01
Autor:
Masanori Yoshida, Kazuhiko Nakabayashi, Wentao Yang, Aiko Sato‐Otsubo, Shin‐ichi Tsujimoto, Hiroko Ogata‐Kawata, Tomoko Kawai, Keisuke Ishiwata, Mika Sakamoto, Kohji Okamura, Kaoru Yoshida, Ryota Shirai, Tomoo Osumi, Chikako Kiyotani, Yoko Shioda, Keita Terashima, Sae Ishimaru, Yuki Yuza, Masatoshi Takagi, Yuki Arakawa, Toshihiko Imamura, Daisuke Hasegawa, Akiko Inoue, Takako Yoshioka, Shuichi Ito, Daisuke Tomizawa, Katsuyoshi Koh, Kimikazu Matsumoto, Nobutaka Kiyokawa, Seishi Ogawa, Atsushi Manabe, Akira Niwa, Kenichiro Hata, Jun J. Yang, Motohiro Kato
Publikováno v:
Cancer Medicine, Vol 12, Iss 10, Pp 11264-11273 (2023)
Abstract Background Second malignant neoplasms (SMNs) are one of the most severe late complications after pediatric cancer treatment. However, the effect of genetic variation on SMNs remains unclear. In this study, we revealed germline genetic factor
Externí odkaz:
https://doaj.org/article/cb1a6a18425b4649bbcf7f5cbbacef02
Autor:
Toyofumi Hirakawa, Kazuhiko Nakabayashi, Noriko Ito, Kenichiro Hata, Shiori Imi, Mami Shibata, Daichi Urushiyama, Kohei Miyata, Fusanori Yotsumoto, Shin’ichiro Yasunaga, Tsukasa Baba, Shingo Miyamoto
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 704 (2024)
Many countries, including Japan, are experiencing declining birth rates. Assisted reproductive technologies have consistently demonstrated good results in resolving infertility. Although the development of fertilized eggs into blastocysts has been re
Externí odkaz:
https://doaj.org/article/53602ed47cd94c85920dfbdab5a3d0fb