Zobrazeno 1 - 10 of 61 pro vyhledávání: '"Kenichi Negoro"'
1
Akademický článek
Collection of patient-generated health data with a mobile application and transfer to hospital information system via QR codes
Autor: Chong Song, Yoichi Kakuta, Kenichi Negoro, Rintaro Moroi, Atsushi Masamune, Erina Sasaki, Naoki Nakamura, Masaharu Nakayama
Publikováno v: Computer Methods and Programs in Biomedicine Update, Vol 3, Iss , Pp 100099- (2023)
Background and Objective: The collection of patient-generated health data (PGHD) is important for understanding a patient's daily status for efficient treatment. Mobile applications are effective for continuously collecting patient data, and it is de
Externí odkaz: https://doaj.org/article/a88624905b41452a881569f390f0ee1f
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3
Akademický článek
Allele-specific DNA methylation of disease susceptibility genes in Japanese patients with inflammatory bowel disease.
Autor: Hirofumi Chiba, Yoichi Kakuta, Yoshitaka Kinouchi, Yosuke Kawai, Kazuhiro Watanabe, Munenori Nagao, Takeo Naito, Motoyuki Onodera, Rintaro Moroi, Masatake Kuroha, Yoshitake Kanazawa, Tomoya Kimura, Hisashi Shiga, Katsuya Endo, Kenichi Negoro, Masao Nagasaki, Michiaki Unno, Tooru Shimosegawa
Publikováno v: PLoS ONE, Vol 13, Iss 3, p e0194036 (2018)
BACKGROUND:Inflammatory bowel disease (IBD) has an unknown etiology; however, accumulating evidence suggests that IBD is a multifactorial disease influenced by a combination of genetic and environmental factors. The influence of genetic variants on D
Externí odkaz: https://doaj.org/article/c4f3cdc67eb747109b4c6644d7862a61
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4
ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis
Autor: Yoshitaka Kinouchi, Motoyuki Onodera, Keiichiro Hiramoto, Tooru Shimosegawa, Tomoya Kimura, Yoshitake Kanazawa, Katsuya Endo, Kenichi Negoro, Masatake Kuroha, Yoichi Kakuta, Hisashi Shiga
Publikováno v: Journal of Gastroenterology and Hepatology. 32:1562-1569
Background and Aim Tacrolimus is now considered to be one of the main therapeutic options for refractory ulcerative colitis. Both cytochrome P-450 3A5 (CYP3A5) and ATP-binding cassette subfamily B member 1 (ABCB1) associated with tacrolimus metabolis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6aba5454fc5d0558e8d472690da6327e
https://doi.org/10.1111/jgh.13753
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5
Increased expression of IL12B mRNA transcribed from the risk haplotype for Crohn’s disease is a risk factor for disease relapse in Japanese patients
Autor: Tooru Shimosegawa, Tomoya Kimura, Yoshitaka Kinouchi, Kenichi Negoro, Katsuya Endo, Hisashi Shiga, Masatake Kuroha, Yoichi Kakuta
Publikováno v: Journal of Gastroenterology. 52:1230-1239
IL12B is a promising candidate for a susceptibility gene in Crohn’s disease (CD). The aim of this study was to perform a candidate gene analysis of IL12B in Japanese CD patients, investigate whether the genotype is associated with disease phenotype
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcd0cd6b6424975c6aa97697eac55076
https://doi.org/10.1007/s00535-017-1322-5
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8
Tacrolimus Dose Optimization Strategy for Refractory Ulcerative Colitis Based on the Cytochrome P450 3A5 Polymorphism Prediction Using Trough Concentration after 24 Hours
Autor: Yoshitaka Kinouchi, Yoshitake Kanazawa, Hisashi Shiga, Motoyuki Onodera, Kenichi Negoro, Tomoya Kimura, Katsuya Endo, Rintaro Moroi, Masatake Kuroha, Yoichi Kakuta, Takeo Naito, Tooru Shimosegawa
Publikováno v: Digestion. 97(1)
Background: In the tacrolimus treatment for refractory ulcerative colitis (UC), dose adjustment is necessary because the required doses to keep appropriate drug concentrations are significantly different among individuals. Cytochrome P450 (CYP) 3A5 p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76706d3297ac92c40042330c66b3eb13
https://pubmed.ncbi.nlm.nih.gov/29393157
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9
ATP-binding cassette subfamily B member 1 1236C/T polymorphism significantly affects the therapeutic outcome of tacrolimus in patients with refractory ulcerative colitis
Autor: Motoyuki, Onodera, Katsuya, Endo, Yoichi, Kakuta, Masatake, Kuroha, Tomoya, Kimura, Keiichiro, Hiramoto, Yoshitake, Kanazawa, Kenichi, Negoro, Hisashi, Shiga, Yoshitaka, Kinouchi, Tooru, Shimosegawa
Publikováno v: Journal of gastroenterology and hepatology. 32(9)
Tacrolimus is now considered to be one of the main therapeutic options for refractory ulcerative colitis. Both cytochrome P-450 3A5 (CYP3A5) and ATP-binding cassette subfamily B member 1 (ABCB1) associated with tacrolimus metabolism are known to have
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8934a7141e5b1390fa26c3f49c6e8857
https://pubmed.ncbi.nlm.nih.gov/28135009
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10
The tumor necrosis factor-alpha promoter -1031C polymorphism is associated with decreased risk of endometriosis in a Japanese population
Autor: Shinya Hamana, Satoru Motoyama, Wang Zhuo, Shigeki Yoshida, Kenichi Negoro, David H. Barlow, Satoshi Nakago, Stephen Kennedy, Takeshi Maruo, Tasneem Asghar
Background Tumor necrosis factor-alpha (TNF-alpha) is a multifunctional proinflammatory cytokine, associated with various inflammatory and autoimmune diseases. Elevated TNF-alpha levels in peritoneal fluid have been reported in women with endometrios
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5513265e9a42daa63fffd04cad63754e
https://ora.ox.ac.uk/objects/uuid:a294a7e1-2b78-4bd1-9e64-fcb1829d853b
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