Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Kenichi Kobayash"'
Autor:
Jeffrey O. Aceves, Szilvia Heja, Kenichi Kobayashi, Sanlin S. Robinson, Tomoya Miyoshi, Takuya Matsumoto, Olivier J. M. Schäffers, Ryuji Morizane, Jennifer A. Lewis
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Three-dimensional, organ-on-chip models that recapitulate kidney tissue are needed for drug screening and disease modeling. Here, we report a method for creating a perfusable 3D proximal tubule model composed of epithelial cells isolated fro
Externí odkaz:
https://doaj.org/article/bc54198737664a13bb87c3de9a98eedf
Autor:
Thiago J. Borges, Yoshikazu Ganchiku, Jeffrey O. Aceves, Ronald van Gaal, Sebastien G.M. Uzel, Ivy A. Rosales, Jonathan E. Rubins, Kenichi Kobayashi, Ken Hiratsuka, Murat Tekguc, Guilherme T. Ribas, Karina Lima, Rodrigo B. Gassen, Ryuji Morizane, Jennifer A. Lewis, Leonardo V. Riella
Publikováno v:
iScience, Vol 27, Iss 10, Pp 110957- (2024)
Summary: The increasing scarcity of organs and the significant morbidity linked to dialysis require the development of engineered kidney tissues from human-induced pluripotent stem cells. Integrative approaches that synergize scalable kidney organoid
Externí odkaz:
https://doaj.org/article/a643a4f97bf94f35ad5928910be26236
Autor:
Yuki Okinaka, Susumu Kageyama, Toshiyuki Goto, Masahiro Sugimoto, Atsumi Tomita, Yumi Aizawa, Kenichi Kobayashi, Akinori Wada, Akihiro Kawauchi, Yosky Kataoka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Patients with advanced cancer are frequently burdened with a severe sensation of fatigue called cancer-related fatigue (CRF). CRF is induced at various stages and treatments, such as cachexia and chemotherapy, and reduces the overall surviva
Externí odkaz:
https://doaj.org/article/bacd1532ff0e4961bd027dc5f0783cee
Publikováno v:
Respirology Case Reports, Vol 12, Iss 4, Pp n/a-n/a (2024)
Abstract Insufficient evidence is available for treating steroid‐resistant immune checkpoint inhibitor pneumonitis (CIP). Although guidelines recommend the use of immunosuppressants, the efficacy of mycophenolate mofetil (MMF) has not been sufficie
Externí odkaz:
https://doaj.org/article/eee970cbdcfc41ef90a5f2afe167ac9f
Autor:
Motoya Hayashi, Yoshinori Honma, Koki Kikuta, Asako Hasegawa, Sayaka Murata, Hiromi Yamada, Masayuki Ogata, Naoki Kagi, U Yanagi, Toshio Yamanaka, Hoon Kim, Kenichi Kobayashi, Noriko Kaihara, Akira Ito, Fumihiko Shinohara, Shoichi Morimoto
Publikováno v:
Japan Architectural Review, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract COVID‐19 outbreaks occurred in several hospitals, and the National Institute of Infectious Diseases, local authorities, and universities carried out investigations into ventilation in hospitals. The results indicated that ventilation perfo
Externí odkaz:
https://doaj.org/article/e805a4818fcd41809fe7a9d77329216a
Autor:
Koichiro Susa, Kenichi Kobayashi, Pierre Galichon, Takuya Matsumoto, Akitoshi Tamura, Ken Hiratsuka, Navin R. Gupta, Iman K. Yazdi, Joseph V. Bonventre, Ryuji Morizane
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Drug nephrotoxicity is a common healthcare problem in hospitalized patients and a major limitation during drug development. Multi-segmented kidney organoids derived from human pluripotent stem cells may complement traditional cell culture and animal
Externí odkaz:
https://doaj.org/article/e2d18dd09a0142409faa4447a4bcf18a
Autor:
Yutaka Inagaki, Yoshiro Kitano, Eishiro Mizukoshi, Shuichi Terasaki, Hiroshi Kawai, Keiji Minouchi, Atsushi Simoda, Takeshi Urabe, Akitaka Nonomura, Kenichi Kobayash, Eiki Matsushita, Sakae Ohba, Masashi Unoura, Shuichi Kaneko, Tomoyuki Nemoto, Masayuki Yanagi
Publikováno v:
Kanzo. 37:331-335
症例は35歳男性.1965年より露光部に紅斑・浮腫が出現し,1987年,赤血球中プロトポルフィジン(PP)の高値より造血性プロトポルフィリン症(EPP)と診断された.1994年,肝障害にて当科入院.入院時
Autor:
Astia Rizki-Safitri, Navin Gupta, Ken Hiratsuka, Kenichi Kobayashi, Chengcheng Zhang, Kazumi Ida, Lisa M. Satlin, Ryuji Morizane
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Kidney organoids derived from hPSCs have opened new opportunities to develop kidney models for preclinical studies and immunocompatible kidney tissues for regeneration. Organoids resemble native nephrons that consist of filtration units and tubules,
Externí odkaz:
https://doaj.org/article/2494cc8c965c4cffb443663848d64f46
Autor:
Katsuya Uchida, Kentaro Hasuoka, Toshimitsu Fuse, Kenichi Kobayashi, Takahiro Moriya, Mao Suzuki, Norihiro Katayama, Keiichi Itoi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract The functional role of thyroid hormone (TH) in the cortex and hippocampus of mouse during neuronal development was investigated in this study. TH insufficiency showed a decrease in the expression of parvalbumin (PV) in the cortex and hippoca
Externí odkaz:
https://doaj.org/article/438d0b2042f04881bf963b816ed5d7bf
Autor:
Motoya Hayashi, U Yanagi, Kenichi Azuma, Naoki Kagi, Masayuki Ogata, Shoichi Morimoto, Hirofumi Hayama, Taro Mori, Koki Kikuta, Shin‐ichi Tanabe, Takashi Kurabuchi, Hiromi Yamada, Kenichi Kobayashi, Hoon Kim, Noriko Kaihara
Publikováno v:
Japan Architectural Review, Vol 3, Iss 4, Pp 423-434 (2020)
Abstract Information on air‐conditioning and ventilation has been continuously disseminated in response to the Japanese Government's announcement of the need for appropriate ventilation measures against the new coronavirus disease (COVID‐19), and
Externí odkaz:
https://doaj.org/article/9e47a6bc554b4d19a1602cbd61817439