Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Kenichi IMAGAWA"'
Publikováno v:
Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics. 39:61-67
Autor:
Yosuke Harada, Akira Nagabukuro, Nobuyuki Koga, Takayuki Shiratsuchi, Masaaki Ohsaki, Junpei Saito, Kenichi Imagawa, Hiroshi Matsushita, Mitsuru Munakata, Takashi Ishida
Publikováno v:
Allergology International. 55:191-198
Background The β2-adrenergic receptor gene ( ADRB2 ) is a target molecule of β2-agonists. Single nucleotide polymorphisms (SNPs) in the ADRB2 are related to the effectiveness of β2-agonists. However, there are some discrepancies in the results of
Autor:
Kenichi Imagawa, Mikio Kikuchi, Shuichi Kaneko, Kenichi Kobayashi, Yoshihiro Sugiyama, Uichiro Fuchizaki, Yasunari Nakamoto
Publikováno v:
Journal of Medical Virology
Although interferon (IFN)-alpha and IFN-gamma have been reported to exhibit a synergistic antiviral effect through the different signaling pathways in vitro, their therapeutic efficacy is not well defined in vivo. The current study was carried out to
Publikováno v:
Journal of The Japan Petroleum Institute. 44:277-285
低級パラフィンの脱水素反応触媒系Sn-Pt/ZnO/γ-アルミナに対して, 細孔構造の精密制御を試みた。シャープな細孔分布の担体を用いることによって, 物理性状 (表面積, 平均細孔径, 細孔容
Publikováno v:
Journal of The Japan Petroleum Institute. 44:286-292
Autor:
Miki Aihara, Mikio Kikuchi, Nobuhiro Sato, Sumio Watanabe, Mitsue Takeda-Ezaki, Kazumi Ishidoh, Kenichi Imagawa, Eiki Kominami
Publikováno v:
Journal of Biochemistry. 125:770-779
Lysosomal proteinases are translated as preproforms, transported through the Golgi apparatus as proforms, and localized in lysosomes as mature forms. In this study, we analyzed which subclass of proteinases participates in the processing of lysosomal
Autor:
Hirokazu Wakebe, Etsuro Shoji, Nobuhiko Takahashi, Yutaka Kohgo, Toshikatsu Okumura, Mikio Kikuchi, Kenichi Imagawa
Publikováno v:
Digestive Diseases and Sciences. 43:90-94
The present study was carried out to investigatethe possibility that lipopolysaccharide deprived fromHelicobacter pylori may alter gastric motility. Toaddress the question, we examined the effect of H. pylori lipopolysaccharide on gastricemptying in
Autor:
Kenichi Imagawa, Takachika Azuma, Yoshihiro Sugiyama, Hidechika Okada, Ken Yamaguchi, Hiroshi Momota, Kyohei Deguchi, Mikio Kikuchi, Miki Aihara, Jiro Hitomi, Masafumi Shibamori, Ozge Alper
Publikováno v:
Japanese Journal of Cancer Research : Gann
With the aim of developing an effective cancer immunotherapy for common epithelial cancer, a new class of bifunctional antibody (BFA) was developed; one arm of this BFA recognized c-erbB-2 gene product, and the other arm recognized CD3 epsilon, a T-c
Autor:
Hisato Kondoh, Mineko Tomomura, Masaru Nakamoto, Takashi Muramatsu, Kenji Kadomatsu, Kenichi Imagawa, Hisako Muramatsu
Publikováno v:
Biochemical and Biophysical Research Communications. 171:603-609
MK is a gene whose expression increases transiently during retinoic acid-induced differentiation of embryonal carcinoma cells. MK polypeptide was secreted by differentiating HM-1 embryonal carcinoma cells and by L-cells transfected with an MK cDNA un
Autor:
Takamitsu Sasaki, Masahiro Hiratsuka, Masaaki Ishikawa, Yumiko Konno, Michinao Mizugaki, Yudai Hinai, Kenichi Imagawa
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 35(10)
Cilostazol (OPC-13013; 6-[4-(1-cyclohexl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone) is widely used as an antiplatelet vasodilator agent. In vitro, the hydroxylation of the quinone moiety of cilostazol to OPC-13326 [6-[4-(1-cyclohexyl-1H-