Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Kenichi Fukai"'
Autor:
Tatsuo Kanda, Osamu Yokosuka, Kenichi Fukai, Makoto Arai, Fuat Kurbanov, Yutaka Yonemitsu, Yasuhito Tanaka, Masashi Mizokami, Fumio Imazeki, Shuang Wu
Publikováno v:
Journal of Hepatology. 54:19-25
Background & Aims Although the evolution of viral quasi-species may be related to the pathological status of disease, little is known about this phenomenon in hepatitis B, particularly with respect to hepatitis B e antigen (HBeAg) seroconversion. Met
Autor:
Osamu Yokosuka, Makoto Arai, Fumio Imazeki, Tatsuo Kanda, Kenichi Fukai, Shuang Wu, Yutaka Yonemitsu
Publikováno v:
Digestive Diseases and Sciences. 56:1207-1214
Although adefovir dipivoxil (ADV) has been used for antiviral treatment of lamivudine (LAM)-resistant chronic hepatitis B (CHB) patients, the long-term efficacy of this treatment is not well understood. Initial virological response (IVR) has been rep
Autor:
Keiichi Fujiwara, Takeyuki Sato, Makoto Arai, Yutaka Yonemitsu, Shigeto Oda, Osamu Yokosuka, Fumio Imazeki, Kenichi Fukai, Akira Watanabe, Tatsuo Kanda
Publikováno v:
Clinical Journal of Gastroenterology. 2:420-424
We report three cases of severe opportunistic infection in patients with acute liver failure (ALF). These cases included a 56-year-old man infected with Cryptococcus neoformans, cytomegarovirus (CMV), Candida albicans and Aspergillus fumigates, as we
Autor:
Yutaka Yonemitsu, Makoto Arai, Yukio Nakatani, Yuichiro Nagai, Fumio Imazeki, Masaru Miyazaki, Osamu Yokosuka, Ryutaro Aoki, Kenichi Fukai, Atsushi Iwama, Satoru Miyagi, Tetsuhiro Chiba
Publikováno v:
Human Pathology. 40:1304-1311
Polycomb gene products play a crucial role in the development of highly malignant phenotypes and aggressive cancer progression in a variety of cancers; however, their role in hepatocellular carcinoma remains unclear. First, we analyzed the impact of
Autor:
Shingo Nakamoto, Kenichi Fukai, Fumihiko Kanai, Fumio Imazeki, Yutaka Yonemitsu, Keiichi Fujiwara, Tatsuo Kanda, Osamu Yokosuka, Makoto Arai
Publikováno v:
Scandinavian Journal of Gastroenterology. 44:872-877
Objective. The effects of hepatitis C virus (HCV) sequence variations on the success of antiviral therapy or the development of hepatocellular carcinoma (HCC) are complex for many reasons. Recently, there have been several reports on the effects of g
Autor:
Fumio Imazeki, Shigeto Oda, Osamu Yokosuka, Makoto Arai, Yutaka Yonemitsu, Keiichi Fujiwara, Hiroshi Suzuki, Akihiro Suzuki, Kenichi Fukai, Shin Yasui, Tomohito Sadahiro
Publikováno v:
Journal of Gastroenterology. 43:711-719
Patients with severe exacerbation of chronic hepatitis B, sometimes developing into fulminant liver failure, are at high risk for mortality even with antiviral therapy. The efficacy of immunosuppressive therapy in clinically severe exacerbation of ch
Autor:
Fumio Imazeki, Osamu Yokosuka, Hiromitsu Saisho, Hiroshige Kojima, Tatsuo Kanda, Kenichi Fukai
Publikováno v:
Liver International. 28:355-362
Background/Aims: Our aim was to evaluate the relationship between hepatitis C virus (HCV) infection and development of diabetes mellitus (DM) or insulin resistance (IR) in comparison with hepatitis B virus (HBV) infection and eradication of HCV infec
Autor:
Kai Yu Zhang, Rintaro Mikata, Fumio Imazeki, Kenichi Fukai, Tatsuo Kanda, Osamu Yokosuka, Makoto Arai
Publikováno v:
Cancer Science. 98:1921-1929
Hepatitis B virus (HBV) genotype C and the basic core promoter (BCP) mutations were reported to be associated with the development of hepatocellular carcinoma (HCC). In this study the full sequences of HBV genomes were analyzed in order to find the o
Publikováno v:
Journal of Viral Hepatitis. 14:661-666
Summary. This study aimed to identify the viral factors responsible for poor sensitivity to lamivudine (LAM). We analyzed 49 LAM-treated chronic hepatitis B patients infected with hepatitis B virus (HBV) genotype C. Serum HBV DNA reached a level belo
Autor:
Narayan Dharel, Osamu Yokosuka, Yasushi Shiratori, Ryosuke Tateishi, Masao Omata, Shuichiro Shiina, Fumio Imazeki, Ryosuke Muroyama, Run-Xuan Shao, Haruhiko Yoshida, Naoya Kato, Masaru Moriyama, Miki Ohta, Motoyuki Otsuka, Yasuo Tanaka, Masashi Tatsukawa, Kenichi Fukai, Yue Wang
Publikováno v:
Journal of Hepatology. 45:805-812
BACKGROUND/AIMS: The hepatitis B virus (HBV) genotype C is associated with the development of hepatocellular carcinoma (HCC). In addition, the HBV X gene, which encodes the pleiotropic transactivator HBx, has also been associated with the development