Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Kenichi, Ohta"'
1
Akademický článek
Conflicting findings on the effectiveness of hydrogen therapy for ameliorating vascular leakage in a 5-day post hypoxic-ischemic survival piglet model
Autor: Yinmon Htun, Shinji Nakamura, Yasuhiro Nakao, Tsutomu Mitsuie, Kenichi Ohta, Makoto Arioka, Takayuki Yokota, Eri Inoue, Kota Inoue, Toi Tsuchiya, Kosuke Koyano, Yukihiko Konishi, Takanori Miki, Masaki Ueno, Takashi Kusaka
Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of morbidity and mortality in newborns in both high- and low-income countries. The important determinants of its pathophysiology are neural cells and vascular components. In neo
Externí odkaz: https://doaj.org/article/549c4ad777984ab19c1a9aaf52145d55
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2
Akademický článek
Cerebral hemodynamic response during the resuscitation period after hypoxic-ischemic insult predicts brain injury on day 5 after insult in newborn piglets
Autor: Yasuhiro Nakao, Shinji Nakamura, Yinmon Htun, Tsutomu Mitsuie, Kosuke Koyano, Kenichi Ohta, Yukihiko Konishi, Takanori Miki, Masaki Ueno, Takashi Kusaka
Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Perinatal hypoxic-ischemic brain injury of neonates remains a significant problem worldwide. During the resuscitation period, changes in cerebral hemoglobin oxygen saturation (ScO2) have been identified by near-infrared spectroscopy (NIRS).
Externí odkaz: https://doaj.org/article/b5dc9182b53348659ff73fff39bb5ec2
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3
Therapeutic potential of hydrogen gas in the reduction of vascular leakage using a 5-day neonatal hypoxic-ischemic piglet model
Autor: Yinmon Htun, Shinji Nakamura, Yasuhiro Nakao, Tsutomu Mitsuie, Kenichi Ohta, Makoto Arioka, Takayuki Yokota, Eri Inoue, Kota Inoue, Toi Tsuchiya, Kosuke Koyano, Yukihiko Konishi, Takanori Miki, Masaki Ueno, Takashi Kusaka
Neonatal hypoxic-ischemic encephalopathy (HIE) is a major cause of morbidity and mortality in newborns in both high- and low-income countries. The important determinants of its pathophysiology are neural cells and vascular components. In neonatal HIE
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b142c1d9b2f9bcc3ced396a8b65b47c1
https://doi.org/10.21203/rs.3.rs-2149232/v1
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4
QM/MM investigation of the degradation mechanism of the electron-transporting layer
Autor: Takeshi Matsushita, Shiro Koseki, Toshio Asada, Kenichi Ohta
Publikováno v: Theoretical Chemistry Accounts. 130:439-448
The mechanism of charge transfer among tris(8-hydroxyquinolinate)aluminum (Alq3) molecules in the electron-transporting layer (ETL) under amorphous conditions was theoretically investigated using both quantum mechanical/molecular mechanical (QM/MM) c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0469ae95407fc40868fea600eafcbb34
https://doi.org/10.1007/s00214-011-1020-y
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5
Rational design of amyloid β peptide–binding proteins: Pseudo-Aβ β-sheet surface presented in green fluorescent protein binds tightly and preferentially to structured Aβ
Autor: Tsuyoshi Takahashi, Hisakazu Mihara, Kenichi Ohta
Publikováno v: Proteins: Structure, Function, and Bioinformatics. 78:336-347
Some neurodegenerative diseases such as Alzheimer disease (AD) and Parkinson disease are caused by protein misfolding. In AD, amyloid beta-peptide (Abeta) is thought to be a toxic agent by self-assembling into a variety of aggregates involving solubl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb4b6916af958dbe440d04ca4f99977
https://doi.org/10.1002/prot.22546
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