Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kenia G. Krauer"'
Autor:
David Leitsch, Kenia G. Krauer, Kevin S. W. Tan, Jacqueline A. Upcroft, Anita Burgess, Lars Eckmann, Peter Upcroft, Linda A. Dunn, Michael Duchêne
Publikováno v:
Journal of Antimicrobial Chemotherapy. 66:1756-1765
Objectives: The mechanism of action of, and resistance to, metronidazole in the anaerobic (or micro-aerotolerant) protozoan parasite Giardia lamblia has long been associated with the reduction of ferredoxin (Fd) by the enzyme pyruvate:ferredoxin oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e2301e45cac9a52e2d0fb36f39f8ca
https://doi.org/10.1093/jac/dkr192
https://doi.org/10.1093/jac/dkr192
Publikováno v:
Journal of General Virology. 87:2879-2884
The Epstein–Barr nuclear antigen 3A (EBNA3A) is one of only six viral proteins essential for Epstein–Barr virus-induced transformation of primary human B cells in vitro. Viral proteins such as EBNA3A are able to interact with cellular proteins, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8f64f129ca2bbd37f87d96d88313411
https://doi.org/10.1099/vir.0.81927-0
https://doi.org/10.1099/vir.0.81927-0
Publikováno v:
Journal of General Virology. 85:165-172
Epstein-Barr virus nuclear antigen (EBNA)-6 is essential for EBV-induced immortalization of primary human B-lymphocytes in vitro. Previous studies have shown that EBNA-6 acts as a transcriptional regulator of viral and cellular genes; however at pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5a7a1eb52c9248648607db4283ffa7
https://doi.org/10.1099/vir.0.19549-0
https://doi.org/10.1099/vir.0.19549-0
Publikováno v:
Transplantation. 73:271-279
Background. Posttransplant lymphoproliferative disease (PTLD), driven by the presence of Epstein-Barr virus (EBV), is becoming an increasingly important clinical problem after solid organ transplantation. The use of immunosuppressive therapy leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::585c93013cec1be8b97346a24abc15fb
https://doi.org/10.1097/00007890-200201270-00021
https://doi.org/10.1097/00007890-200201270-00021
Publikováno v:
Journal of General Virology. 80:3217-3226
RBP, a transcriptional repressor, is intricately involved in Epstein–Barr virus (EBV) transformation of human B cells. The EBV nuclear proteins EBNA-2, -3, -4 and -6 all utilize RBP to regulate the transcription of both cellular and viral genes. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d3d88fb01e31c63590b8a8ac9fb5b6
https://doi.org/10.1099/0022-1317-80-12-3217
https://doi.org/10.1099/0022-1317-80-12-3217
Publikováno v:
Journal of Virology. 73:8902-8906
The cellular localization of the Epstein-Barr virus-encoded RK-BARF0 protein was analyzed by fluorescence microscopy and immunoblotting. The recombinant RK-BARF0 protein was found to be tightly bound to nuclear structures, whereas 16- to 20-kDa RK-BA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae56a013b0f807f821d3f43d73e72bb
https://doi.org/10.1128/jvi.73.10.8902-8906.1999
https://doi.org/10.1128/jvi.73.10.8902-8906.1999
Autor:
Ian F. C. McKenzie, Sarah M. Andrew, Jin Ghee Teh, Kenia G. Krauer, Hamish McA Foster, Geoffrey A. Pietersz, Mark J. Smyth
Publikováno v:
Immunology and Cell Biology. 71:167-179
Tumour cell heterogeneity is probably a principal cause of treatment failure and represents a formidable barrier for effective antibody-targeted chemotherapy. Idarubicin (Ida), a more potent and less cardiotoxic analogue of daunomycin, has been demon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2272abfdc762f938610373bb2b5510d8
https://doi.org/10.1038/icb.1993.19
https://doi.org/10.1038/icb.1993.19
Publikováno v:
Drug Delivery. 1:27-33
Drug–antibody conjugates are undergoing close scrutiny as new antitumor agents because they confer increased drug specificity, producing higher accumulation in the tumor and less systemic toxicity than free drug. Consequently this has led to the us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84b2a8db5ff91d52f45a468d8a6b886
https://doi.org/10.3109/10717549309031338
https://doi.org/10.3109/10717549309031338
Publikováno v:
The Journal of parasitology. 96(3)
The gut protozoan parasite, Giardia lamblia (Assemblage A), has 5 major chromosomes, 1 of which is 2 Mb, as determined from gel separations of whole chromosomes. We originally published a physical map of this chromosome and, now, using the sequence d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828bf22f40ace6a62c4ee2a5a3bab282
https://pubmed.ncbi.nlm.nih.gov/20557214
https://pubmed.ncbi.nlm.nih.gov/20557214
Autor:
Anita Burgess, Linda A. Dunn, Kenia G. Krauer, Zygmunt Kazimierczuk, Jacqueline A. Upcroft, Peter Upcroft, Janelle M. Wright
Publikováno v:
Parasitology research. 107(4)
This study investigates the susceptibility of a clinically metronidazole (Mz)-resistant isolate of Trichomonas vaginalis to alternative anti-trichomonal compounds. The microaerobic minimal inhibitory concentration (MIC) of the 5-nitroimidazole (NI) d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc1362dea48594f8f9ce22c37598df6
https://pubmed.ncbi.nlm.nih.gov/20532912
https://pubmed.ncbi.nlm.nih.gov/20532912