Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kengyuan Qu"'
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110409- (2024)
Summary: PU.1 (SPI1) is pivotal in hematopoiesis, yet its role in human endothelial-to-hematopoietic transition (EHT) remains unclear. Comparing human in vivo and in vitro EHT transcriptomes revealed SPI1’s regulatory role. Knocking down SPI1 durin
Externí odkaz:
https://doaj.org/article/a5569b62223741b38c5228dc1546d065
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract Hemogenic endothelium (HE) with hematopoietic stem cell (HSC)-forming potential emerge from specialized arterial endothelial cells (AECs) undergoing the endothelial-to-hematopoietic transition (EHT) in the aorta-gonad-mesonephros (AGM) regio
Externí odkaz:
https://doaj.org/article/05a9dc899dad41cbb22b701315b43b4d
Autor:
Shuo Zhang, Kengyuan Qu, Shuzhen Lyu, Dixie L. Hoyle, Cory Smith, Linzhao Cheng, Tao Cheng, Jun Shen, Zack Z. Wang
Publikováno v:
Journal of Cellular Physiology. 238:179-194
Hemogenic endothelial (HE) cells are specialized endothelial cells to give rise to hematopoietic stem/progenitor cells during hematopoietic development. The underlying mechanisms that regulate endothelial-to-hematopoietic transition (EHT) of human HE
Autor:
Shuo Zhang, Kengyuan Qu, Shuzhen Lyu, Hoyle, Dixie L., Smith, Cory, Linzhao Cheng, Tao Cheng, Jun Shen, Wang, Zack Z.
Publikováno v:
Journal of Cellular Physiology; Jan2023, Vol. 238 Issue 1, p179-194, 16p