Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kengo, Tejima"'
Publikováno v:
PLoS Genetics, Vol 20, Iss 11, p e1011436 (2024)
While single-cell RNA-sequencing (scRNA-seq) is a popular method to analyze gene expression and cellular composition at single-cell resolution, it harbors shortcomings: The failure to account for cell-to-cell variations of transcriptome-size (i.e., t
Externí odkaz:
https://doaj.org/article/80aedc14d2344734a3c09844e82be694
Autor:
Satoshi Kozawa, Kengo Tejima, Shunki Takagi, Masataka Kuroda, Mari Nogami-Itoh, Hideya Kitamura, Takashi Niwa, Takashi Ogura, Yayoi Natsume-Kitatani, Thomas N. Sato
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease characterized by complex lung pathogenesis affecting approximately three million people worldwide. While the molecular and cellular details of the IPF mechanism is emer
Externí odkaz:
https://doaj.org/article/1030cbd97fb94eb3b9cb7eeb4bde49c2
Autor:
Michiyo Okamoto, Azusa Takahashi-Nakaguchi, Kengo Tejima, Kaname Sasamoto, Masashi Yamaguchi, Toshihiro Aoyama, Minoru Nagi, Kohichi Tanabe, Yoshitsugu Miyazaki, Hironobu Nakayama, Chihiro Sasakawa, Susumu Kajiwara, Alistair J. P. Brown, Miguel C. Teixeira, Hiroji Chibana
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi, cholesterol uptake is an important strategy for decreasing susceptibility to antifungals that
Externí odkaz:
https://doaj.org/article/032d13171c144ec89662613b0415c996
Autor:
Satoshi Kozawa, Hirona Yokoyama, Kyoji Urayama, Kengo Tejima, Hotaka Doi, Shunki Takagi, Thomas N Sato
Publikováno v:
Bioinformatics Advances. 3
Motivation Human diseases are characterized by multiple features such as their pathophysiological, molecular and genetic changes. The rapid expansion of such multi-modal disease-omics space provides an opportunity to re-classify diverse human disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3facc80b25e8392ecde35163c614ba78
https://doi.org/10.1093/bioadv/vbad047
https://doi.org/10.1093/bioadv/vbad047
Publikováno v:
Journal of Fungi, Vol 5, Iss 4, p 88 (2019)
The lipophilic fungal pathogen Malassezia spp. must acquire long-chain fatty acids (LCFAs) from outside the cell. To clarify the mechanism of LCFA acquisition, we investigated fatty acid uptake by this fungus and identified the long-chain acyl-CoA sy
Externí odkaz:
https://doaj.org/article/1420e2977e454c288e5a901707cc48eb
Autor:
Michiyo, Okamoto, Azusa, Takahashi-Nakaguchi, Kengo, Tejima, Kaname, Sasamoto, Masashi, Yamaguchi, Toshihiro, Aoyama, Minoru, Nagi, Kohichi, Tanabe, Yoshitsugu, Miyazaki, Hironobu, Nakayama, Chihiro, Sasakawa, Susumu, Kajiwara, Alistair J P, Brown, Miguel C, Teixeira, Hiroji, Chibana
Publikováno v:
Frontiers in cell and developmental biology. 10
The uptake of cholesterol from the host is closely linked to the proliferation of pathogenic fungi and protozoa during infection. For some pathogenic fungi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7bb1cd0a2d7397060a1b88eddbdbbb13
https://pubmed.ncbi.nlm.nih.gov/35399500
https://pubmed.ncbi.nlm.nih.gov/35399500
Computational deconvolution of transcriptome data of organs/tissues uncovers their structural and functional complexities at cellular resolution without performing single-cell RNA-sequencing experiments. However, the deconvolution of highly heterogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19de48744b041d289208f0a927755b40
https://doi.org/10.1101/2020.07.05.188276
https://doi.org/10.1101/2020.07.05.188276
Publikováno v:
Journal of Fungi
Volume 5
Issue 4
Journal of Fungi, Vol 5, Iss 4, p 88 (2019)
Volume 5
Issue 4
Journal of Fungi, Vol 5, Iss 4, p 88 (2019)
The lipophilic fungal pathogen Malassezia spp. must acquire long-chain fatty acids (LCFAs) from outside the cell. To clarify the mechanism of LCFA acquisition, we investigated fatty acid uptake by this fungus and identified the long-chain acyl-CoA sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb42e2923153d94f8b95f90e1999336
Publikováno v:
Current genetics. 64(2)
Fatty acyl-CoA synthetase (Faa) activates fatty acid (FA) by converting the FA into the CoA ester in the cell. In the present study, we characterized a FAA homologue (CaFAA4) from the opportunistic pathogen Candida albicans. Most organisms can not on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9a90b7c6e04a2f097910b8d6d88f73
https://pubmed.ncbi.nlm.nih.gov/28942495
https://pubmed.ncbi.nlm.nih.gov/28942495
Publikováno v:
Current Genetics; Apr2018, Vol. 64 Issue 2, p429-441, 13p