Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Keng-Boon Lee"'
Publikováno v:
Proceedings of the National Academy of Sciences. 99:4239-4244
Transcription-coupled repair (TCR) is essential for the rapid, preferential removal of DNA damage in active genes. The large subunit of RNA polymerase (Pol) II is ubiquitinated in cells after UV-irradiation or cisplatin treatment, which induces DNA d
Autor:
Steve Church, William Matthes, Nikhil J. Bhatt, Mona M. Abaza, Kanwar Kelley, Ayesha N. Khalid, Keng-Boon Lee
Publikováno v:
Otolaryngology–Head and Neck Surgery. 151
Program Description:Physicians must confront significant financial issues over the course of their careers. These issues can be especially problematic for young physicians entering practice, although decisions around professional and personal finance
Publikováno v:
Gene. 225:97-105
Screening of cDNA libraries for the homologous vertebrate proteins high mobility group (HMG) 1 and 2 using DNA probes based on the coding sequences is likely to result in isolation of both HMG1 and HMG2 clones, as well as pseudogenes, which may be tr
Autor:
Kenglu Tan, Johan Fagan, J. Pablo Stolovitzky, Nancy L. Snyderman, Gregory W. Randolph, David W. Kennedy, Bernard Fraysse, Jaime Fandino Izundegui, Eugene N. Myers, Keng-Boon Lee, James C. Saunders, George Muhlfay
Publikováno v:
Otolaryngology–Head and Neck Surgery. 147
Publikováno v:
Journal of molecular biology. 360(1)
The high-mobility group protein HMGB1 contains two tandem DNA-binding HMG box domains, A and B, linked by a short flexible linker that allows the two domains to behave independently in the free protein. There is no structural information on how the l
Autor:
Phillip A. Sharp, Keng Boon Lee
Publikováno v:
Biochemistry. 43(48)
Lysine-63-linked polyubiquitin chains are not thought to signal protein degradation but instead signal for a variety of cellular processes including some types of DNA repair. RNA polymerase (Pol) II is polyubiquitinated following DNA damage or upon t
Publikováno v:
Journal of molecular biology. 309(1)
DNA minicircles, where the length of DNA is below the persistence length, are highly effective, preferred, ligands for HMG-box proteins. The proteins bind to them "structure-specifically" with affinities in the nanomolar range, presumably to an expos
Autor:
Keng-Boon Lee, Jean O. Thomas
Publikováno v:
Journal of molecular biology. 304(2)
The high-mobility group (HMG) proteins HMG1, HMG2 and HMG2a are relatively abundant vertebrate DNA-binding and bending proteins that bind with structure specificity, rather than sequence specificity, and appear to play an architectural role in the as
Autor:
Keng-Boon Lee, Klaus D. Grasser, Soo Hwang Teo, R. William Broadhurst, Jean O. Thomas, C. H. Hardman, Christine Rees
Publikováno v:
European journal of biochemistry. 253(3)
High-mobility-group protein 1 (HMG1) is a conserved chromosomal protein with two homologous DNA-binding HMG-box domains, A and B, linked by a short basic region to an acidic carboxy-terminal tail. NMR spectroscopy on the free didomain (AB) shows that
Autor:
David W. Kennedy, G. Richard Holt, Ronald B. Kuppersmith, J. Regan Thomas, Gregory W. Randolph, Ramon j. Franco, Terry A. Day, Karl Hörmann, Eugene N. Myers, J. Pablo Stolovitzky, Keng-Boon Lee, James L. Netterville, Nikhil J. Bhatt, James E. Saunders
Publikováno v:
Otolaryngology–Head and Neck Surgery. 143:718-718