Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Keng Mean Lin"'
Autor:
Jing Zhang, Yuehan Wei, Yangbo Yue, Huike Jiao, Yan Wu, Wan Fu, Keng-Mean Lin, Lu, Christopher, Shan Mou, Qing Zhong
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/1/2024, Vol. 121 Issue 40, p1-11, 41p
Autor:
Natarajan, Madhusudan1,2, Keng-Mean Lin1,2, Hsueh, Robert C.1,2, Sternweis, Paul C.1,2, Ranganathan, Rama2,3 rama.ranganathan@utsouthwestern.edu
Publikováno v:
Nature Cell Biology. Jun2006, Vol. 8 Issue 6, p571-580. 10p. 1 Diagram, 6 Graphs.
Autor:
Christopher Y. Lu, Glenn T. Nagami, Keng Mean Lin, Xin J. Zhou, Yanxia Wang, James A. Richardson, John R. Hartono, Pamela D. Winterberg, John M. Shelton
Publikováno v:
American Journal of Physiology-Renal Physiology. 305:F164-F172
We previously reported that expression of the transcription factor interferon regulatory factor 1 (IRF1) is an early, critical maladaptive signal expressed by renal tubules during murine ischemic acute kidney injury (AKI). We now show that IRF1 media
Autor:
Robert A. Rebres, Melvin I. Simon, Leah A. Santat, William E. Seaman, Elliott M. Ross, Finly Philip, Tamara I. A. Roach, Iain D. C. Fraser, Keng Mean Lin, Lucas Cheadle, Christina Moon, Jamie Liu
Publikováno v:
Journal of Biological Chemistry. 286:942-951
Cross-talk between Gα(i)- and Gα(q)-linked G-protein-coupled receptors yields synergistic Ca(2+) responses in a variety of cell types. Prior studies have shown that synergistic Ca(2+) responses from macrophage G-protein-coupled receptors are primar
Autor:
H. Alex Brown, Iain D. C. Fraser, William E. Seaman, Tamara I. A. Roach, Robert A. Rebres, Christina Moon, Dianne L. DeCamp, Stephen B. Milne, Keng-Mean Lin
Publikováno v:
Journal of Leukocyte Biology. 87:1041-1057
Distinct activities of toxin B up-regulate PLCβ3 or down-regulate PLCβ4-dependent IP3-Ca2+ coupling. Clostridium difficile toxins cause acute colitis by disrupting the enterocyte barrier and promoting inflammation. ToxB from C. difficile inactivate
Autor:
Keng Mean Lin, Dianne L. DeCamp, Paul C. Sternweis, M. I. Simon, Tamara I. A. Roach, Robert A. Rebres, William E. Seaman, Iain D. C. Fraser
Publikováno v:
Journal of Biological Chemistry. 283:17351-17361
Studies in fibroblasts, neurons, and platelets have demonstrated the integration of signals from different G protein-coupled receptors (GPCRs) in raising intracellular free Ca(2+). To study signal integration in macrophages, we screened RAW264.7 cell
Autor:
Ronald Taussig, Robert C. Hsueh, Richard Davis, Tamara I. A. Roach, Paul C. Sternweis, Keng Mean Lin, Iain D. C. Fraser, Robert A. Rebres, Elliott M. Ross, Lily I. Jiang, Dianne L. DeCamp, Julie Collins
Publikováno v:
Journal of Biological Chemistry. 282:10576-10584
Regulation of intracellular cyclic adenosine 3 ',5 '-monophosphate (cAMP) is integral in mediating cell growth, cell differentiation, and immune responses in hematopoietic cells. To facilitate studies of cAMP regulation we developed a BRET (biolumine
Autor:
Jens Kroll, Toru Miyazaki, Thomas N. Sato, Xiaozhong Shi, Arianna Caprioli, Hong Hsing Liu, Hans Reimer Rodewald, Claudia Waskow, Keng Mean Lin
Publikováno v:
Molecular and Cellular Biology. 25:8531-8540
BTB-kelch proteins can elicit diverse biological functions but very little is known about the physiological role of these proteins in vivo. Kelch-like protein 6 (KLHL6) is a BTB-kelch protein with a lymphoid tissue-restricted expression pattern. In t
Autor:
Sun Young Lee, Xiaocui Zhu, Keng-Mean Lin, Jong-Woo Kim, Dennis Mock, Melvin I. Simon, Mi Sook Chang, Brian Saunders, Robert C. Hsueh, Sangdun Choi, Shankar Subramaniam, Paul C. Sternweis, Eugene Ke, Yun Anna Cao, David A. Fruman, William E. Seaman, Angela Alexander, Zhen Yan, Jamie A. Lee, Joella Grossoehme, Rebecca Hart, Richard H. Scheuermann
Publikováno v:
The Journal of Immunology. 173:7141-7149
We examined the major patterns of changes in gene expression in mouse splenic B cells in response to stimulation with 33 single ligands for 0.5, 1, 2, and 4 h. We found that ligands known to directly induce or costimulate proliferation, namely, anti-
Autor:
Richard B. Gaynor, Carmela Lamberti, Yumi Yamamoto, Inder M. Verma, Keng Mean Lin, Steven Byers, Udit Verma
Publikováno v:
Journal of Biological Chemistry. 276:42276-42286
Both the β-catenin and the nuclear factor κB (NF-κB) proteins are important regulators of gene expression and cellular proliferation. Two kinases, IKKα and IKKβ, are critical activators of the NF-κB pathway. Here we present evidence that these