Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kendra Tosoni"'
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149550 (2016)
BACKGROUND:Precision medicine aims to combat the variability of the therapeutic response to a given medicine by delivering the right medicine to the right patient. However, the application of precision medicine is predicated on a prior quantitation o
Externí odkaz:
https://doaj.org/article/5bcc68ec5dea4b228e178779056b6f94
Autor:
Andrea Venerando, Cinzia Franchin, Natasha Cant, Giorgio Cozza, Mario A Pagano, Kendra Tosoni, Ateeq Al-Zahrani, Giorgio Arrigoni, Robert C Ford, Anil Mehta, Lorenzo A Pinna
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74232 (2013)
By mass spectrometry analysis of mouse Cystic Fibrosis Transmembrane-conductance Regulator (mCFTR) expressed in yeast we have detected 21 phosphopeptides accounting for 22 potential phospho-residues, 12 of which could be unambiguously assigned. Most
Externí odkaz:
https://doaj.org/article/68fbd49b21d3481aa67880cbdc47ab55
Autor:
Simão Luz, Carlos M. Farinha, Mario A. Pagano, Michelle Stobbart, Kendra Tosoni, Margarida D. Amaral, Andrea Venerando, Diane Cassidy, Anil Mehta, Karl Kunzelmann, Lorenzo A. Pinna
Publikováno v:
Biochemical Journal
Most CF (cystic fibrosis) results from deletion of a phenylalanine (F508) in the CFTR {CF transmembrane-conductance regulator; ABCC7 [ABC (ATP-binding cassette) sub-family C member 7]} which causes ER (endoplasmic reticulum) degradation of the mutant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa8abef31c0e4a0c8fc59f0cc78d838
https://pubmed.ncbi.nlm.nih.gov/23067305
https://pubmed.ncbi.nlm.nih.gov/23067305
Autor:
Stefano D'Alessandro, Kendra Tosoni, Alex Costa, Francesca Sparla, Michela Zottini, Maria Ruzzene, Stefania Sarno, Lorenzo A. Pinna
Publikováno v:
Molecular and Cellular Biochemistry
Molecular and Cellular Biochemistry, Springer Verlag, 2011, 356 (1-2), pp.245-254. ⟨10.1007/s11010-011-0969-0⟩
Molecular and Cellular Biochemistry, 2011, 356 (1-2), pp.245-254. ⟨10.1007/s11010-011-0969-0⟩
Molecular and Cellular Biochemistry, Springer Verlag, 2011, 356 (1-2), pp.245-254. ⟨10.1007/s11010-011-0969-0⟩
Molecular and Cellular Biochemistry, 2011, 356 (1-2), pp.245-254. ⟨10.1007/s11010-011-0969-0⟩
The ubiquitous Ser/Thr protein kinase CK2, which phosphorylates hundreds of substrates and is essential for cell life, plays important roles also in plants; however, only few plant substrates have been identified so far. During a study aimed at ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::645d70f66249d87786bce821f33a0124
https://hal-amu.archives-ouvertes.fr/hal-03303941
https://hal-amu.archives-ouvertes.fr/hal-03303941
At variance with protein kinases expressed by oncogenes, CK2 is endowed with constitutive activity under normal conditions, and no CK2 gain-of-function mutants are known. Its amount, however, is abnormally high in malignant cells where it appears to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cba29d2080e608d2d9158ee206c251db
http://hdl.handle.net/11577/2478467
http://hdl.handle.net/11577/2478467
At variance with the great majority of protein kinases that become active only in response to specific stimuli and whose implication in tumors is caused by genetic alterations conferring to them unscheduled activity, the highly pleiotropic Ser/Thr-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f335a21005575f74738277ac0ec06a94
https://doi.org/10.1016/b978-0-12-381298-8.00024-1
https://doi.org/10.1016/b978-0-12-381298-8.00024-1
At variance with the great majority of protein kinases that become active only in response to specific stimuli and whose implication in tumors is caused by genetic alterations conferring to them unscheduled activity, the highly pleiotropic Ser/Thr-sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ed3a8216d8e2af78176a8c6236792f10
http://hdl.handle.net/11577/118227
http://hdl.handle.net/11577/118227
Autor:
Lorenzo A. Pinna, Stefanie-Dorothea Krämer, Giovanni Di Maira, Maria Ruzzene, Kendra Tosoni, Sara Belli, F Brustolon
CK2 is a pleiotropic protein kinase, which phosphorylates many substrates and has a global role in promoting cell survival and preventing apoptosis. In this study, we investigated its involvement in the phenomenon of the drug resistance, by which tum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1632e2aaec2076f87ea52d627104e9a9
http://hdl.handle.net/11577/2452605
http://hdl.handle.net/11577/2452605
Autor:
Kendra Tosoni, Lorenzo A. Pinna, Livio Trentin, Marianna Gnoato, Renato Zambello, Giorgio Arrigoni, Anna Cabrelle, Luca Bonanni, Carmela Gurrieri, Laura Quotti Tubi, Gianpietro Semenzato, Maria Ruzzene, Francesco Piazza
Publikováno v:
Università degli Studi di Padova-IRIS
Acute Promyelocytic Leukemia, (APL, M3 FAB-subtype) is characterized by the chromosomal translocation t(15;17) and the expression of the oncogenic fusion protein PML-RARα (promyelocytic leukemia gene-retinoic acid receptor -α); this AML subtype is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efc43bbb6349aec43f19577023c44b2
http://hdl.handle.net/11577/181917
http://hdl.handle.net/11577/181917
Autor:
Sandra Marmiroli, Jessika Bertacchini, Kendra Tosoni, G. Di Maira, F Brustolon, Maria Ruzzene, La Pinna
Protein kinase CK2 is an ubiquitous and constitutively active kinase, which phosphorylates many cellular proteins and is implicated in the regulation of cell survival, proliferation and transformation. We investigated its possible involvement in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c47d3e29d02bb114a013fab616421693
http://hdl.handle.net/11577/2449022
http://hdl.handle.net/11577/2449022