Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Kendra M. Fleming"'
Publikováno v:
Nutrients, Vol 15, Iss 11, p 2494 (2023)
Obesity, a known risk factor of Alzheimer’s disease (AD), increases the activation of microglia, leading to a proinflammatory phenotype. Our previous work shows that a high fat diet (HFD) can cause neuroinflammation and cognitive decline in mice. W
Externí odkaz:
https://doaj.org/article/5a822f27b9934947bc72c006f0f17773
Autor:
Simon W. So, Kendra M. Fleming, Cayla M. Duffy, Joshua P. Nixon, David A. Bernlohr, Tammy A. Butterick
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4354 (2022)
The microglial fatty-acid-binding protein 4-uncoupling protein 2 (FABP4-UCP2) axis is a key regulator of neuroinflammation in high-fat-diet (HFD)-fed animals, indicating a role for FABP4 in brain immune response. We hypothesized that the FABP4-UCP2 a
Externí odkaz:
https://doaj.org/article/bc7406ef60eb4457ba6fb4972b96c28c