Gut inflammation associated with age and Alzheimer’s disease pathology: a human cohort study

Autor: Margo B. Heston, Kendra L. Hanslik, Katie R. Zarbock, Sandra J. Harding, Nancy J. Davenport-Sis, Robert L. Kerby, Nathaniel Chin, Yi Sun, Ana Hoeft, Yuetiva Deming, Nicholas M. Vogt, Tobey J. Betthauser, Sterling C. Johnson, Sanjay Asthana, Gwendlyn Kollmorgen, Ivonne Suridjan, Norbert Wild, Henrik Zetterberg, Kaj Blennow, Federico E. Rey, Barbara B. Bendlin, Tyler K. Ulland

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract Age-related disease may be mediated by low levels of chronic inflammation (“inflammaging”). Recent work suggests that gut microbes can contribute to inflammation via degradation of the intestinal barrier. While aging and age-related dise

Externí odkaz: https://doaj.org/article/506736e3f4d7449a8334c7f95494e88c

The Role of Microglia and the Nlrp3 Inflammasome in Alzheimer's Disease

Autor: Kendra L. Hanslik, Tyler K. Ulland

Publikováno v: Frontiers in Neurology, Vol 11 (2020)

Alzheimer's disease (AD) is the most prevalent form of late-onset dementia. AD affects the health of millions of people in the United States and worldwide. Currently, there are no approved therapies that can halt or reverse the clinical progression o

Externí odkaz: https://doaj.org/article/2f16a3a189f84e3686ec3daac329c330

GABA promotes survival and axonal regeneration in identifiable descending neurons after spinal cord injury in larval lampreys

Autor: Daniel Romaus-Sanjurjo, Kendra L. Hanslik, Blanca Fernández-López, Antón Barreiro-Iglesias, Jennifer R. Morgan, Rocio Ledo-Garcia, María Celina Rodicio

Publikováno v: Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
instname
Cell Death and Disease, Vol 9, Iss 6, Pp 1-15 (2018)
Cell Death & Disease

The poor regenerative capacity of descending neurons is one of the main causes of the lack of recovery after spinal cord injury (SCI). Thus, it is of crucial importance to find ways to promote axonal regeneration. In addition, the prevention of retro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3619bc245639ebe0f0d49a47d0608b7c
https://hdl.handle.net/10347/17645

Regenerative capacity in the lamprey spinal cord is not altered after a repeated transection.

Autor: Kendra L Hanslik, Scott R Allen, Tessa L Harkenrider, Stephanie M Fogerson, Eduardo Guadarrama, Jennifer R Morgan

Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0204193 (2019)

The resilience of regeneration in vertebrates is not very well understood. Yet understanding if tissues can regenerate after repeated insults, and identifying limitations, is important for elucidating the underlying mechanisms of tissue plasticity. T

Externí odkaz: https://doaj.org/article/f351abcf42154b48bf17897f4304b285