Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Kendra L. Burgher"'
Autor:
Kendra L. Burgher, Chun C Chao, Sheng Zu Zhu, Garth E. Ringheim, Ann Marie Szczepanik, Wayne Petko
Publikováno v:
Molecular Brain Research. 55:35-44
We investigated a potential role for the soluble interleukin-6 receptor (sIL-6R) in modulating interleukin-6 (IL-6) function in the central nervous system by assessing IL-6 and sIL-6R effects on beta-amyloid precursor protein (beta-APP) transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b2c17404fe8a655610bd9a67fe41559
https://doi.org/10.1016/s0169-328x(97)00356-2
https://doi.org/10.1016/s0169-328x(97)00356-2
Publikováno v:
Neurochemistry International. 30:483-489
Astrocytes in culture have been previously shown to express inducible nitric oxide synthase (iNOS) following treatment with cytokines such as interleukin-1 beta (IL-1 beta) and interferon-gamma (IFN-gamma). We report here on the effects of the cyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5566999fcbc7c520f7fd0677dbd8a847
https://doi.org/10.1016/s0197-0186(96)00085-x
https://doi.org/10.1016/s0197-0186(96)00085-x
Autor:
Sam Kongsamut, Deborah E. Bregna, Lisa L. Kerman, Joachim E. Roehr, ‡ and Ann T. Woods-Kettelberger, Mark R. Szewczak, Harold B. Hartman, Jurcak John G, Roy Corbett, Hrib Nicholas J, Kendra L. Burgher, Sharon H. Kafka
Publikováno v:
Journal of Medicinal Chemistry. 39:4044-4057
HP-236 (3-[4-[4-(6-Fluorobenzo[b]thien-3-yl)-1-piperazinyl]butyl]-2,5,5- trimethyl-4-thiazolidinone maleate; P-9236) (54) displayed a pharmacological profile indicative of potential atypical antipsychotic activity. A series of piperazinyl butyl thiaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70f34f27b11f91b1bf373c26201d52ba
https://doi.org/10.1021/jm960268u
https://doi.org/10.1021/jm960268u
Publikováno v:
Journal of Neuroimmunology. 63:113-123
In this study, we investigated the capacity of murine cortical neurons to express interleukin-6 (IL-6) mRNA and protein in culture. Using in situ hybridization techniques, IL-6 mRNA was localized to neuronal cells in these cultures. Moreover, IL-6 mR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2d27b57f109e6f79bad06c97baf00c8
https://doi.org/10.1016/0165-5728(95)00134-4
https://doi.org/10.1016/0165-5728(95)00134-4
Autor:
Paul G. Conway, Joachim E. Roehr, Kendra L. Burgher, Jurcak John G, L. L. Kerman, Harold B. Hartman, Hrib Nicholas J, Woods Ann Theresa
Publikováno v:
Journal of Medicinal Chemistry. 37:2308-2314
A series of benzisoxaazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity. In general, the compounds showed an affinity for dopamine D 2 and serotonin 5HT 2A and 5HT 1A receptors. Several members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c19b10bad7a6db7d13bbed8e553a51f
https://doi.org/10.1021/jm00041a009
https://doi.org/10.1021/jm00041a009
Autor:
Paul G. Conway, Joachim E. Roehr, Hrib Nicholas J, L. L. Kerman, Kendra L. Burgher, Jurcak John G, Woods Ann Theresa, Harold B. Hartman
Publikováno v:
ChemInform. 25
A series of benzisoxaazole- and benzisothiazole-3-carboxamides has been prepared and tested for potential antipsychotic activity. In general, the compounds showed an affinity for dopamine D 2 and serotonin 5HT 2A and 5HT 1A receptors. Several members
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02112b01fc223667afdc88ea96b60e59
https://doi.org/10.1002/chin.199451169
https://doi.org/10.1002/chin.199451169
Autor:
Mark R. Szewczak, H. B. Hartmann, S. Kongsamut, L. L. Kerman, A. T. Woods-Kettelberger, R. Corbett, Kendra L. Burgher, Jurcak John G, Hrib Nicholas J, D. E. Bregna, Joachim E. Roehr, S. Kafka
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d852ddf2afb7063c3006d371c15674ab
https://doi.org/10.1002/chin.199704180
https://doi.org/10.1002/chin.199704180
Autor:
Kendra L. Burgher, Garth E. Ringheim, Jeffrey A. Heroux, Filippo Cavalieri, Ann Marie Szcepanik, Wayne Petko
Publikováno v:
Biochemical and biophysical research communications. 224(1)
Attenuating beta-amyloid precursor protein (beta-APP) gene expression may have relevance in diseases such as Alzheimer's disease, where beta-APP has been implicated in neuropathological processes. We report here on the transcriptional down-regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2268b3eec5c52b88d6ba389e3f5720dd
https://pubmed.ncbi.nlm.nih.gov/8694821
https://pubmed.ncbi.nlm.nih.gov/8694821
The activation of cultured Raw 264.7 murine macrophages with interferon γ and lipopolysaccharide results in the expression of inducible nitric oxide synthase (i-NOS) and the subsequent production of nitric oxide. In the present study, the i-NOS expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d44c7c6d64994b5e704a070c79c6c2
https://europepmc.org/articles/PMC1217140/
https://europepmc.org/articles/PMC1217140/
