Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kendra L Gully"'
Autor:
John N Snouwaert, Leigh A Jania, Trang Nguyen, David R Martinez, Alexandra Schäfer, Nicholas J Catanzaro, Kendra L Gully, Ralph S Baric, Mark Heise, Martin T Ferris, Elizabeth Anderson, Katia Pressey, Jacob A Dillard, Sharon Taft-Benz, Victoria K Baxter, Jenny P-Y Ting, Beverly H Koller
Publikováno v:
PLoS Pathogens, Vol 19, Iss 2, p e1011168 (2023)
Angiotensin-converting enzyme 2 (ACE2), part of the renin-angiotensin system (RAS), serves as an entry point for SARS-CoV-2, leading to viral proliferation in permissive cell types. Using mouse lines in which the Ace2 locus has been humanized by synt
Externí odkaz:
https://doaj.org/article/75be0b479d294111a5b725cdfbedb42c
Autor:
Alexandra Schäfer, Sarah R. Leist, Lisa E. Gralinski, David R. Martinez, Emma S. Winkler, Kenichi Okuda, Padraig E. Hawkins, Kendra L. Gully, Rachel L. Graham, D. Trevor Scobey, Timothy A. Bell, Pablo Hock, Ginger D. Shaw, Jennifer F. Loome, Emily A. Madden, Elizabeth Anderson, Victoria K. Baxter, Sharon A. Taft-Benz, Mark R. Zweigart, Samantha R. May, Stephanie Dong, Matthew Clark, Darla R. Miller, Rachel M. Lynch, Mark T. Heise, Roland Tisch, Richard C. Boucher, Fernando Pardo Manuel de Villena, Stephanie A. Montgomery, Michael S. Diamond, Martin T. Ferris, Ralph S. Baric
Publikováno v:
mBio, Vol 13, Iss 4 (2022)
ABSTRACT Infectious diseases have shaped the human population genetic structure, and genetic variation influences the susceptibility to many viral diseases. However, a variety of challenges have made the implementation of traditional human Genome-wid
Externí odkaz:
https://doaj.org/article/0653e049732d4652b9b825ecba93c24d
Autor:
Aaron F. Carlin, James R. Beadle, Alex E. Clark, Kendra L. Gully, Fernando R. Moreira, Ralph S. Baric, Rachel L. Graham, Nadejda Valiaeva, Sandra L. Leibel, William Bray, Rachel E. McMillan, Jonathan E. Freshman, Aaron F. Garretson, Rachael N. McVicar, Tariq Rana, Xing-Quan Zhang, Joyce A. Murphy, Robert T. Schooley, Karl Y. Hostetler
Publikováno v:
Journal of Medicinal Chemistry. 66:5802-5819
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ce6028f5c0e95a9874dc2527a27c35
https://doi.org/10.1021/acs.jmedchem.3c00046
https://doi.org/10.1021/acs.jmedchem.3c00046
Autor:
Kenneth H. Dinnon, Sarah R. Leist, Kenichi Okuda, Hong Dang, Ethan J. Fritch, Kendra L. Gully, Gabriela De la Cruz, Mia D. Evangelista, Takanori Asakura, Rodney C. Gilmore, Padraig Hawkins, Satoko Nakano, Ande West, Alexandra Schäfer, Lisa E. Gralinski, Jamie L. Everman, Satria P. Sajuthi, Mark R. Zweigart, Stephanie Dong, Jennifer McBride, Michelle R. Cooley, Jesse B. Hines, Miriya K. Love, Steve D. Groshong, Alison VanSchoiack, Stefan J. Phelan, Yan Liang, Tyler Hether, Michael Leon, Ross E. Zumwalt, Lisa M. Barton, Eric J. Duval, Sanjay Mukhopadhyay, Edana Stroberg, Alain Borczuk, Leigh B. Thorne, Muthu K. Sakthivel, Yueh Z. Lee, James S. Hagood, Jason R. Mock, Max A. Seibold, Wanda K. O’Neal, Stephanie A. Montgomery, Richard C. Boucher, Ralph S. Baric
Publikováno v:
Science Translational Medicine. 14
A subset of individuals who recover from coronavirus disease 2019 (COVID-19) develop post-acute sequelae of SARS-CoV-2 (PASC), but the mechanistic basis of PASC-associated lung abnormalities suffers from a lack of longitudinal tissue samples. The mou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebc038fbf6d04ca8c03eceeb0f72973e
https://doi.org/10.1126/scitranslmed.abo5070
https://doi.org/10.1126/scitranslmed.abo5070
Autor:
Kenneth H. Dinnon, Sarah R. Leist, Kenichi Okuda, Hong Dang, Ethan J. Fritch, Kendra L. Gully, Gabriela De la Cruz, Mia D. Evangelista, Takanori Asakura, Rodney C. Gilmore, Padraig Hawkins, Satoko Nakano, Ande West, Alexandra Schäfer, Lisa E. Gralinski, Jamie L. Everman, Satria P. Sajuthi, Mark R. Zweigart, Stephanie Dong, Jennifer McBride, Michelle R. Cooley, Jesse B. Hines, Miriya K. Love, Steve D. Groshong, Alison VanSchoiack, Stefan J. Phelan, Yan Liang, Tyler Hether, Michael Leon, Ross E. Zumwalt, Lisa M. Barton, Eric J. Duval, Sanjay Mukhopadhyay, Edana Stroberg, Alain Borczuk, Leigh B. Thorne, Muthu K. Sakthivel, Yueh Z. Lee, James S. Hagood, Jason R. Mock, Max A. Seibold, Wanda K. O’Neal, Stephanie A. Montgomery, Richard C. Boucher, Ralph S. Baric
Publikováno v:
bioRxiv : the preprint server for biology.
COVID-19 survivors develop post-acute sequelae of SARS-CoV-2 (PASC), but the mechanistic basis of PASC-associated lung abnormalities suffers from a lack of longitudinal samples. Mouse-adapted SARS-CoV-2 MA10 produces an acute respiratory distress syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c3bceca188f05d6c7291ce768e22b2
https://pubmed.ncbi.nlm.nih.gov/35194605
https://pubmed.ncbi.nlm.nih.gov/35194605
Autor:
Alexandra Schäfer, David R. Martinez, John J. Won, Rita M. Meganck, Fernando R. Moreira, Ariane J. Brown, Kendra L. Gully, Mark R. Zweigart, William S. Conrad, Samantha R. May, Stephanie Dong, Rao Kalla, Kwon Chun, Venice Du Pont, Darius Babusis, Jennifer Tang, Eisuke Murakami, Raju Subramanian, Kimberly T. Barrett, Blake J. Bleier, Roy Bannister, Joy Y. Feng, John P. Bilello, Tomas Cihlar, Richard L. Mackman, Stephanie A. Montgomery, Ralph S. Baric, Timothy P. Sheahan
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 3
article-version (status) pre
article-version (number) 3
The coronavirus disease 2019 (COVID-19) pandemic remains uncontrolled despite the rapid rollout of safe and effective severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines, underscoring the need to develop highly effective antivirals.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414bac2018cc4bd1b40a45769213931b
Autor:
John M. Powers, Sarah R. Leist, Michael L. Mallory, Boyd L. Yount, Kendra L. Gully, Mark R. Zweigart, Alexis B. Bailey, Timothy P. Sheahan, Jack R. Harkema, Ralph S. Baric
Publikováno v:
Virus Research, Vol 341, Iss , Pp 199319- (2024)
Following the emergence of B.1.1.529 Omicron, the SARS-CoV-2 virus evolved into a significant number of sublineage variants that possessed numerous mutations throughout the genome, but particularly within the spike glycoprotein (S) gene. For example,
Externí odkaz:
https://doaj.org/article/648a023997b5452d8143bd9154ef6965
Autor:
Lily E. Adams, Sarah R. Leist, Kenneth H. Dinnon, III, Ande West, Kendra L. Gully, Elizabeth J. Anderson, Jennifer F. Loome, Emily A. Madden, John M. Powers, Alexandra Schäfer, Sanjay Sarkar, Izabella N. Castillo, Jenny S. Maron, Ryan P. McNamara, Harry L. Bertera, Mark R. Zweigert, Jaclyn S. Higgins, Brea K. Hampton, Lakshmanane Premkumar, Galit Alter, Stephanie A. Montgomery, Victoria K. Baxter, Mark T. Heise, Ralph S. Baric
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112326- (2023)
Summary: Group 2B β-coronaviruses (sarbecoviruses) have caused regional and global epidemics in modern history. Here, we evaluate the mechanisms of cross-sarbecovirus protective immunity, currently less clear yet important for pan-sarbecovirus vacci
Externí odkaz:
https://doaj.org/article/7da7f2fa9eee4314bfa59cc3b0f22f10