Výsledky vyhledávání - "Kendra Garchow"

In Vitro Studies on Degradation of Gamma-L-Glutamyl-L-Cysteine and Gamma-L-Glutamyl-D-Cysteine in Blood

Autor: Kendra Garchow, Ernest J. Sukowski, Nsisong Ikpa, Darryl R. Peterson, Rachel Forman

Publikováno v: American Journal of Therapeutics. 22:e97-e106

Treatment for ischemic stroke involves a thrombolytic agent to re-establish blood flow in the brain. However, delayed reperfusion may cause injury to brain capillaries. Previous studies indicate that the antioxidant gamma-L-glutamyl-L-cysteine (γ-Gl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304b925789e476d95e07bbfd4f2f0e13
https://doi.org/10.1097/mjt.0000000000000246

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Treatment with the Matricellular Protein CCN3 Blocks and/or Reverses Fibrosis Development in Obesity with Diabetic Nephropathy

Autor: Kendra Garchow, Bruce L. Riser, Ernest J. Sukowski, Feridoon Najmabadi, Jeffrey L. Barnes, Darryl R. Peterson

Publikováno v: The American Journal of Pathology. 184:2908-2921

Fibrosis is at the core of the high morbidity and mortality rates associated with the complications of diabetes and obesity, including diabetic nephropathy (DN), without any US Food and Drug Administration–approved drugs with this specific target.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2e386b2f20a41e93fe56dd019a543b
https://doi.org/10.1016/j.ajpath.2014.07.009

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CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure

Autor: Tatiana Tsoutsman, Bruce L. Riser, Kendra Garchow, Christopher Semsarian, Xiaoyu Wang, Stephen M. Twigg

Publikováno v: Journal of Molecular and Cellular Cardiology. 62:164-178

Hypertrophic cardiomyopathy (HCM) is the most common inherited primary myocardial disorder. HCM is characterized by interstitial fibrosis and excessive accumulation of extracellular matrix (ECM) proteins. Fibrosis in HCM has been associated with impa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45607e7861f2ff53474e58aee004da9c
https://doi.org/10.1016/j.yjmcc.2013.05.019

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Gadolinium-induced fibrosis is counter-regulated by CCN3 in human dermal fibroblasts: a model for potential treatment of nephrogenic systemic fibrosis

Autor: Narasimharao Bhagavathula, Patricia Perone, Gary J. Fisher, James Varani, Yiru Xu, Durga Attili, Kendra Garchow, Feridoon Najmabadi, Bruce L. Riser

We recently show that CCN3 is a counter-regulatory molecule for the pro-fibrotic protein CCN2, and a potentially novel fibrosis therapy. The goal of this study was to assess the role of CCN3 in fibroproliferative/fibrotic responses in human dermal fi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d700dcff363027ea46eb4d480933c9
https://europepmc.org/articles/PMC3368017/

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CCN2/CTGF Plays a Key Role in Extracellular Matrix Gene Expression in Severe Hypertrophic Cardiomyopathy and Heart Failure

Autor: Bruce L. Riser, C. Semsarian, Xiaoyu Wang, Kendra Garchow, Stephen M. Twigg, Tatiana Tsoutsman

Publikováno v: Heart, Lung and Circulation. 22:S54

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::126c39988604c5ced205fc813958c464
https://doi.org/10.1016/j.hlc.2013.05.130

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