Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Kendle M Maslowski"'
Autor:
Alastair Copland, Gillian M Mackie, Lisa Scarfe, Elizabeth Jinks, David A J Lecky, Nancy Gudgeon, Riahne McQuade, Masahiro Ono, Manja Barthel, Wolf-Dietrich Hardt, Hiroshi Ohno, Wilma H M Hoevenaar, Sarah Dimeloe, David Bending, Kendle M Maslowski
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3057-3088 (2024)
Abstract Bacterial cancer therapy (BCT) is a promising therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification and metabolic adaptation. A longstanding p
Externí odkaz:
https://doaj.org/article/c6c0ef49a7a64b2b9004b01d4c713943
Autor:
Mario M Zaiss, Kendle M Maslowski, Ilaria Mosconi, Nadine Guenat, Benjamin J Marsland, Nicola L Harris
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003531 (2013)
Approximately 2 billion people currently suffer from intestinal helminth infections, which are typically chronic in nature and result in growth retardation, vitamin A deficiency, anemia and poor cognitive function. Such chronicity results from co-evo
Externí odkaz:
https://doaj.org/article/ea0d2da95e834f6a818035fb444b9af8
Autor:
Gillian M. Mackie, Alastair Copland, Masumi Takahashi, Yumiko Nakanishi, Isabel Everard, Tamotsu Kato, Hirotsugu Oda, Takashi Kanaya, Hiroshi Ohno, Kendle M. Maslowski
Publikováno v:
JCI Insight, Vol 6, Iss 23 (2021)
Bacterial cancer therapy (BCT) shows great promise for treatment of solid tumors, yet basic mechanisms of bacterial-induced tumor suppression remain undefined. Attenuated strains of Salmonella enterica serovar Typhimurium (STm) have commonly been use
Externí odkaz:
https://doaj.org/article/725159422a1549a79387894d2b459170
Autor:
Emma L. Bishop, Nancy H. Gudgeon, Gillian M. Mackie, Daniel Chauss, Jennie Roberts, Daniel A. Tennant, Kendle M. Maslowski, Behdad Afzali, Martin Hewison, Sarah Dimeloe
Publikováno v:
Immunology. 166:299-309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14a637766e7491d42b0ff48179477951
https://doi.org/10.1111/imm.13472
https://doi.org/10.1111/imm.13472
Autor:
Alastair Copland, Gillian M. Mackie, Lisa Scarfe, David A.J. Lecky, Nancy Gudgeon, Riahne McQuade, Masahiro Ono, Manja Barthel, Wolf-Dietrich Hardt, Hiroshi Ohno, Sarah Dimeloe, David Bending, Kendle M. Maslowski
SummaryBacterial cancer therapy (BCT) is a promising therapeutic for solid tumours.Salmonella entericaTyphimurium (STm) is well-studied amongst bacterial vectors due to advantages in genetic modification and metabolic adaptation. A longstanding parad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdef840a53f9760c119927240987e121
https://doi.org/10.1101/2023.01.12.523780
https://doi.org/10.1101/2023.01.12.523780
Publikováno v:
Biochemical Society Transactions
The gut relies on the complex interaction between epithelial, stromal and immune cells to maintain gut health in the face of food particles and pathogens. Innate sensing by the intestinal epithelium is critical for maintaining epithelial barrier func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e37795ebd4d71c7990e571ba712e810
https://doi.org/10.1042/bst20210365
https://doi.org/10.1042/bst20210365
Autor:
Thomas A E Elliot, Emma K Jennings, David A J Lecky, Sophie Rouvray, Gillian M Mackie, Lisa Scarfe, Lozan Sheriff, Masahiro Ono, Kendle M Maslowski, David Bending
Publikováno v:
Discovery Immunology. 1
In lymphocytes, Nr4a gene expression is specifically regulated by antigen receptor signalling, making them ideal targets for use as distal T cell receptor (TCR) reporters. Nr4a3-Timer of cell kinetics and activity (Tocky) mice are a ground-breaking t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99d64b4f4f24e4fccb344db5d1a1081c
https://doi.org/10.1093/discim/kyac009
https://doi.org/10.1093/discim/kyac009
Autor:
Nicolas Bonadies, Joerg C. Schefold, Aubry Tardivel, Eric Chi-Wang Yu, Vedat Burak Ozan, Thibaud Spinetti, Esther Youd, Amiq Gazdhar, Kendle M. Maslowski, Ramanjaneyulu Allam, Pascal Schneider, Cédric Hirzel, Matthew Pugh, Mayuresh Anant Sarangdhar, Anne Angelillo-Scherrer, Giuseppe Bombaci, Graham S. Taylor, Yara Banz, Gillian M Mackie, Nicola Andina
Inflammasomes are cytosolic innate immune sensors of pathogen infection and cellular damage that induce caspase-1 mediated inflammation upon activation. Although inflammation is protective, uncontrolled excessive inflammation can cause inflammatory d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f2b115e460eb414c2a9e1f238495ed2
https://doi.org/10.1101/2021.04.12.438219
https://doi.org/10.1101/2021.04.12.438219
Autor:
Adriana Flores-Langarica, Kendle M. Maslowski, Natasha Thawait, Thomas A.E. Elliot, Alastair Copland, David Bending, Emma K. Jennings, David A.J. Lecky, David C. Wraith
Publikováno v:
Immunity
Summary How T cell receptor (TCR) signal strength modulates T cell function and to what extent this is modified by immune checkpoint blockade (ICB) are key questions in immunology. Using Nr4a3-Tocky mice, we characterized early quantitative and quali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f43037d602993e7db87f2fde608beb0a
https://pubmed.ncbi.nlm.nih.gov/34534438
https://pubmed.ncbi.nlm.nih.gov/34534438
Autor:
Yumiko Nakanishi, Gillian M Mackie, Masumi Takahashi, Kendle M. Maslowski, Hirotsugu Oda, Isabel Everard, Takashi Kanaya, Hiroshi Ohno, Tamotsu Kato, Alastair Copland
Publikováno v:
JCI Insight
Bacterial cancer therapy (BCT) shows great promise for treatment of solid tumors, yet basic mechanisms of bacterial-induced tumor suppression remain undefined. Attenuated strains of Salmonella enterica serovar Typhimurium (STm) have commonly been use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b5695cac287da20e59b72ed3fa7c8a4
https://pubmed.ncbi.nlm.nih.gov/34710062
https://pubmed.ncbi.nlm.nih.gov/34710062