The multifaceted roles of mass spectrometric analysis in nucleic acids drug discovery and development.

Autor: Kenderdine, Thomas¹ (AUTHOR), Fabris, Dan¹ (AUTHOR) dan.fabris@uconn.edu

Publikováno v: Mass Spectrometry Reviews. Jul2023, Vol. 42 Issue 4, p1332-1357. 26p.

High‐resolution ion mobility spectrometry‐mass spectrometry of isomeric/isobaric ribonucleotide variants.

Autor: Kenderdine, Thomas¹ (AUTHOR), Nemati, Reza² (AUTHOR), Baker, Andrew³ (AUTHOR), Palmer, Martin³ (AUTHOR), Ujma, Jakub³ (AUTHOR), FitzGibbon, Molly^1,4 (AUTHOR), Deng, Limin¹ (AUTHOR), Royzen, Maksim¹ (AUTHOR), Langridge, James³ (AUTHOR), Fabris, Daniele¹ (AUTHOR) fabris@albany.edu

Publikováno v: Journal of Mass Spectrometry. Feb2020, Vol. 55 Issue 2, p1-11. 11p.

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Suppression of mutant C9orf72 expression by a potent mixed backbone antisense oligonucleotide.

Autor: Tran H; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Moazami MP; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Yang H; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., McKenna-Yasek D; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Douthwright CL; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Pinto C; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Metterville J; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Shin M; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA., Sanil N; Research Pharmacy, University of Massachusetts Medical School, Worcester, MA, USA., Dooley C; Research Pharmacy, University of Massachusetts Medical School, Worcester, MA, USA., Puri A; Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA., Weiss A; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Wightman N; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA., Gray-Edwards H; Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA., Marosfoi M; Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA., King RM; Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA.; Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, USA., Kenderdine T; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Fabris D; Department of Chemistry, University of Connecticut, Storrs, CT, USA., Bowser R; Departments of Neurology and Neurobiology, Barrow Neurological Institute, Phoenix, AZ, USA., Watts JK; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA. jonathan.watts@umassmed.edu., Brown RH Jr; Department of Neurology, University of Massachusetts Medical School, Worcester, MA, USA. robert.brown@umassmed.edu.

Publikováno v: Nature medicine [Nat Med] 2022 Jan; Vol. 28 (1), pp. 117-124. Date of Electronic Publication: 2021 Dec 23.