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pro vyhledávání: '"Kendarius J. Butler"'
Autor:
Jason C. Hurlbert, Morgan T. Turnow, Mikala R. Smith, William E. Cotham, Angel A. Castro, Caylie A. McGlade, Kevin M. Mays, Louise M. Hardwick, Tiffany S. Dwyer, Kendarius J. Butler, Sara G. Manore, Lisa N. Hair, Michael D. Walla, Melody C. Iacino, T. Christian Grattan, Matthew R. Wilson, Stephanie R. Woodson, Erin W. Parker
Publikováno v:
Bioorg Med Chem Lett
The sphingomyelin pathway is important in cell regulation and determining cellular fate. Inhibition of sphingosine kinase isoform 1 (SK1) within this pathway, leads to a buildup of sphingosine and ceramide, two molecules directly linked to cell apopt