Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kendall Mitchell"'
Publikováno v:
Journal of Molecular Neuroscience. 63:308-319
Chronic inflammation mediated by persistent microglial activation is associated with the pathogenesis of neurodegenerative diseases. The mechanisms underlying chronic microglial activation are poorly understood. We have previously shown that anti-inf
Autor:
Lyubov V. Tsytsikova, Jill P. Shah, Ashley M. Campbell, Kendall Mitchell, Aviva J. Symes, Kwame Ofori Affram
Publikováno v:
Journal of Neurochemistry. 129:155-168
Accumulating evidence indicates that activated microglia contribute to the neuropathology involved in many neurodegenerative diseases and after traumatic injury to the CNS. The cytokine transforming growth factor-beta 1 (TGF-β1), a potent deactivato
Autor:
Ashley C. Tipton, Anton E. Dmitriev, Jill P. Shah, Kendall Mitchell, Aviva J. Symes, Clifton L. Dalgard, Lyubov V. Tsytsikova
Publikováno v:
BMC Neuroscience
Background Bone morphogenetic protein-2 (BMP-2) is a pleiotropic, secreted molecule with diverse effects. The potent ability of BMP-2 to stimulate bone growth prompted its widespread clinical use for arthrodesis (spine fusion). However, elevated post
Autor:
Brian D. Bates, William D. Swaim, Andrew J. Mannes, Kendall Mitchell, Michael J. Iadarola, Chi-Chao Chan, Ruth Yaskovich, Jason M. Keller
Publikováno v:
Pain. 149:522-528
Analgesics currently available for the treatment of pain following ophthalmic surgery or injury are limited by transient effectiveness and undesirable or adverse side effects. The cornea is primarily innervated by small-diameter C-fiber sensory neuro
Publikováno v:
Anesthesia & Analgesia. 109:959-964
After surgery, cytokines and chemokines are released at the surgical wound site, which can contribute to postoperative pain, local inflammation, and tissue repair. Multiple cell types are present that can release cytokines/chemokines at the wound sit
Autor:
Evan E. Lebovitz, Jason M. Keller, Michael I. Nemenov, Kendall Mitchell, Andrew J. Mannes, Michael J. Iadarola
TRPV1 is expressed in a subpopulation of myelinated Aδ and unmyelinated C-fibers. TRPV1+ fibers are essential for the transmission of nociceptive thermal stimuli and for the establishment and maintenance of inflammatory hyperalgesia. We have previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4707c7a628831c84a5d752762e7f5876
https://europepmc.org/articles/PMC4567256/
https://europepmc.org/articles/PMC4567256/
Autor:
Kendall Mitchell, Michael J. Iadarola
Publikováno v:
Methods in Molecular Biology ISBN: 9781603273220
Frequently, it is important to ascertain whether a molecule that is involved in one model of pain is also involved in other models of pain. Similarly, it may be important to determine whether a molecule involved in nociception in one tissue is also e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3600e9f49b01adc494ffaa408091f2df
https://doi.org/10.1007/978-1-60327-323-7_21
https://doi.org/10.1007/978-1-60327-323-7_21
Publikováno v:
Journal of neurochemistry. 103(4)
The sensation of pain (nociception) is a critical factor in host defense during tissue injury and inflammation and is initiated at the site of injury by activation of primary afferent C-fiber and A- partial differential nerve endings. Inflammation in
Autor:
Katalin Karikó, Jason M. Keller, Yolanda Rangel, Frank A. Welsh, Valerie A. Harris, Kendall Mitchell
Publikováno v:
Brain research. Molecular brain research. 96(1-2)
Previous studies have demonstrated that preconditioning the brain with cortical spreading depression (CSD) induces tolerance to a subsequent episode of ischemia. In other models of preconditioning, induction of ischemic tolerance has been associated
Autor:
Kendall Mitchell, Brian D. Bates, Jason M. Keller, Andrew J. Mannes, Michael J. Iadarola, Michael I. Nemenov
Publikováno v:
The Journal of Pain. 11:S40