Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kendall Kearns"'
Publikováno v:
International Journal of Infectious Diseases, Vol 141, Iss , Pp 106983- (2024)
Objectives: Tuberculosis (TB) remains a global health challenge due to various factors, including delayed diagnoses leading to the spread of infection, limited efficacy of current vaccination strategies, and emergence of drug-resistant strains. Here,
Externí odkaz:
https://doaj.org/article/c7e56da5535049f49db369356c9df184
Autor:
Rashmi Tippalagama, Leila Y. Chihab, Kendall Kearns, Sloan Lewis, Sudhasini Panda, Lisa Willemsen, Julie G. Burel, Cecilia S. Lindestam Arlehamn
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Antigen-specific T cells play a central role in the adaptive immune response and come in a wide range of phenotypes. T cell receptors (TCRs) mediate the antigen-specificities found in T cells. Importantly, high-throughput TCR sequencing provides a fi
Externí odkaz:
https://doaj.org/article/d886030d7409475fbb9c72670ca8056c
Autor:
Daniel B. Goodman, Camillia S. Azimi, Kendall Kearns, Alexis Talbot, Kiavash Garakani, Julie Garcia, Nisarg Patel, Byungjin Hwang, David Lee, Emily Park, Vivasvan S. Vykunta, Brian R. Shy, Chun Jimmie Ye, Justin Eyquem, Alexander Marson, Jeffrey A. Bluestone, Kole T. Roybal
Publikováno v:
Science translational medicine, vol 14, iss 670
Chimeric antigen receptors (CARs) repurpose natural signaling components to retarget T cells to refractory cancers but have shown limited efficacy in persistent, recurrent malignancies. Here, we introduce “CAR Pooling,” a multiplexed approach to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a86774c205dff95513b6cbc907d3d1bc
https://doi.org/10.1126/scitranslmed.abm1463
https://doi.org/10.1126/scitranslmed.abm1463
Autor:
David Lee, Byungjin Hwang, Jeff A. Bluestone, Alexander Marson, Emily Park, Kiavash Garakani, Kole T. Roybal, Camillia S. Azimi, Chun Jimmie Ye, Julie M. Garcia, Daniel B. Goodman, Kendall Kearns, Nisarg Patel
SUMMARYChimeric antigen receptors (CARs) repurpose natural signaling components to retarget T cells to refractory cancers, but have shown limited efficacy against solid tumors. Here, we introduce ‘CAR Pooling’, a multiplexed approach to rapidly i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec3cfd0d36d5b832e1bd16b495f03c20
https://doi.org/10.1101/2021.07.11.451980
https://doi.org/10.1101/2021.07.11.451980
Autor:
Susan Chen, Thomas Stevens, Eric C. Wong, Graham Heimberg, Kara J. Helmke, David Dinh, John Haliburton, Priyanka Dadlani, Veronica Zepeda, Benjamin M. Heineike, Kendall Kearns, Derrick Lee, Weiyue Ji, Wendell A. Lim, Sherry Teng, Verna Huang, Lei S. Qi, Anusuya Ramasubramanian
Publikováno v:
ACS Synthetic Biology
In microbial communities, bacterial populations are commonly controlled using indiscriminate, broad range antibiotics. There are few ways to target specific strains effectively without disrupting the entire microbiome and local environment. Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75354763ed6155d5645c31bb5744332a
https://doi.org/10.1021/sb500036q
https://doi.org/10.1021/sb500036q