Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kenanao P. Kotokwe"'
Autor:
Sikhulile Moyo, Simani Gaseitsiwe, Terence Mohammed, Molly Pretorius Holme, Rui Wang, Kenanao Peggy Kotokwe, Corretah Boleo, Lucy Mupfumi, Etienne Kadima Yankinda, Unoda Chakalisa, Erik van Widenfelt, Tendani Gaolathe, Mompati O Mmalane, Scott Dryden-Peterson, Madisa Mine, Refeletswe Lebelonyane, Kara Bennett, Jean Leidner, Kathleen E Wirth, Eric Tchetgen Tchetgen, Kathleen Powis, Janet Moore, William A Clarke, Shahin Lockman, Joseph M Makhema, Max Essex, Vlad Novitsky
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204840 (2018)
BACKGROUND:Botswana is close to reaching the UNAIDS "90-90-90" HIV testing, antiretroviral treatment (ART), and viral suppression goals. We sought to determine HIV incidence in this setting with both high HIV prevalence and high ART coverage. METHODS
Externí odkaz:
https://doaj.org/article/481e5df9b97e429b860ec5ba1e5dfe3d
Autor:
Phyllis J. Kanki, Simani Gaseitsiwe, Vladimir Novitsky, Roger L. Shapiro, Shahin Lockman, Charlotte A. Chang, Catherine K. Koofhethile, Kenanao P. Kotokwe, Joseph Makhema, Myron Essex, Tulio de Oliveira, Sikhulile Moyo, Selebogo Mokgweetsi, Lorato Muchoba, Patrick Mokgethi
Publikováno v:
AIDS Res Hum Retroviruses
Although antiretroviral therapy (ART) effectively suppresses HIV replication, the latent reservoir remains the barrier to HIV eradication. It remains unknown whether long-term ART impacts levels of inducible replication-competent provirus. To address
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a963ab8ca90fa25254addb219d337f28
https://doi.org/10.1089/aid.2020.0097
https://doi.org/10.1089/aid.2020.0097
Autor:
Sikhulile Moyo, Alain Vandormael, Eduan Wilkinson, Susan Engelbrecht, Simani Gaseitsiwe, Kenanao P Kotokwe, Rosemary Musonda, Frank Tanser, Max Essex, Vladimir Novitsky, Tulio de Oliveira
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160649 (2016)
BACKGROUND:Cross-sectional, biomarker methods to determine HIV infection recency present a promising and cost-effective alternative to the repeated testing of uninfected individuals. We evaluate a viral-based assay that uses a measure of pairwise dis
Externí odkaz:
https://doaj.org/article/7afeb4c2ef8643bcb5b824d6a60dfbc6
Autor:
Catherine K. Koofhethile, Myron Essex, Simani Gaseitsiwe, Joseph Makhema, Phyllis J. Kanki, Sikhulile Moyo, Lorato Muchoba, Roger L. Shapiro, Patrick Mokgethi, Vladimir Novitsky, Shahin Lockman, Tendani Gaolathe, Tulio de Oliveira, Selebogo Mokgweetsi, Kenanao P. Kotokwe
Publikováno v:
Medicine
Rationale: Early initiation of antiretroviral therapy (ART) leads to long-term viral suppression, reduces proviral reservoir size, and prolongs time to rebound. Since human immunodeficiency virus (HIV) is a lifelong disease, diagnostic monitoring aft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36648435e0f70ec98675bd302bb03f8a
https://pubmed.ncbi.nlm.nih.gov/31764816
https://pubmed.ncbi.nlm.nih.gov/31764816
Autor:
Jia Weng, Alain Vandormael, Max Essex, Sikhulile Moyo, Vladimir Novitsky, Eduan Wilkinson, Rui Wang, Kenanao P. Kotokwe, Simani Gaseitsiwe, Tulio de Oliveira, Susan Engelbrecht, Rosemary Musonda, Joseph Makhema
Publikováno v:
Virus Evolution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4ddf40554f66a0cc9f5fe8f71041fea
https://doi.org/10.1093/ve/vey010
https://doi.org/10.1093/ve/vey010
Autor:
Vladimir Novitsky, Susan Engelbrecht, Simani Gaseitsiwe, Joseph Makhema, Jia Weng, Sikhulile Moyo, Eduan Wilkinson, Rosemary Musonda, Alain Vandormael, Rui Wang, Max Essex, Kenanao P. Kotokwe, Tulio de Oliveira
Publikováno v:
Medicine
Intrahost human immunodeficiency virus (HIV)-1 diversity increases linearly over time. We assessed the extent to which mean pairwise distances and the time to the most recent common ancestor (tMRCA) inferred from intrahost HIV-1C env sequences were a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532677bc919c2f90541b0f56f380829a
http://europepmc.org/articles/PMC5313003
http://europepmc.org/articles/PMC5313003
Autor:
Vladimir Novitsky, Tulio de Oliveira, Simani Gaseitsiwe, Rosemary Musonda, Max Essex, Sikhulile Moyo, Alain Vandormael, Frank Tanser, Eduan Wilkinson, Susan Engelbrecht, Kenanao P. Kotokwe
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0160649 (2016)
PLoS ONE, Vol 11, Iss 8, p e0160649 (2016)
BACKGROUND:Cross-sectional, biomarker methods to determine HIV infection recency present a promising and cost-effective alternative to the repeated testing of uninfected individuals. We evaluate a viral-based assay that uses a measure of pairwise dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab997bbae358149780b9f2c8677fc38
https://pubmed.ncbi.nlm.nih.gov/27552218
https://pubmed.ncbi.nlm.nih.gov/27552218
Autor:
Kenanao P. Kotokwe, Vladimir Novitsky, Lucy Mupfumi, Terence Mohammed, Rosemary Musonda, Max Essex, Samuel Chishala, Hermann Bussmann, Sikhulile Moyo, Joseph Makhema, Lesedi Tsalaile, Simani Gaseitsiwe, Marianna K Baum, Susan Engelbrecht, Corettah Boleo, Richard Marlink
Publikováno v:
AIDS Research and Human Retroviruses. 33:17-18
Cross-sectional estimation of HIV incidence could misclassify some established or chronic HIV infections as recent. Usually long-term nonprogressors, elite and viremic controllers, and individuals on ART contribute to misclassification. Local data on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9ee453f6976d1d3467e88e94276f26e
https://doi.org/10.1089/aid.2016.0127
https://doi.org/10.1089/aid.2016.0127
Autor:
Madisa Mine, Lucy Mupfumi, Terence Mohammed, Vlad Novitsky, Janet Moore, Erik van Widenfelt, Joseph Makhema, Mompati Mmalane, Kenanao P. Kotokwe, Simani Gaseitsiwe, Corretah Boleo, Jean Leidner, William Clarke, Max Essex, Kathleen M. Powis, Shahin Lockman, Sikhulile Moyo, Molly Pretorius Holme, Unoda Chakalisa, Kathleen E. Wirth, Tendani Gaolathe, Refeletswe Lebelonyane, Etienne Kadima Yankinda, Scott Dryden-Peterson, Rui Wang, Kara Bennett, Eric J. Tchetgen Tchetgen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204840 (2018)
PLoS ONE, Vol 13, Iss 10, p e0204840 (2018)
Background Botswana is close to reaching the UNAIDS "90-90-90" HIV testing, antiretroviral treatment (ART), and viral suppression goals. We sought to determine HIV incidence in this setting with both high HIV prevalence and high ART coverage. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::013ab6cb00d093712e95983770133734
https://doi.org/10.1371/journal.pone.0204840
https://doi.org/10.1371/journal.pone.0204840
Autor:
Coretah Boleo, Lucy Mupfumi, Herman Bussmann, Vladimir Novitsky, Richard Marlink, Terence Mohammed, Lesedi Tsalaile, Joseph Makhema, Simani Gaseitsiwe, Susan Engelbretch, Marianna K Baum, Kenanao P. Kotokwe, Samuel Chishala, Sikhulile Moyo, Max Essex
Publikováno v:
BMJ Global Health. 2:A34.1-A34
Background Cross-sectional tests for recency of HIV infection are increasing in utility for estimating HIV incidence and evaluating impact of interventions. However, they have been shown to misclassify individuals with long standing infection as rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c28ed5439f9cd28359e1f8f8b8eb9af
https://doi.org/10.1136/bmjgh-2016-000260.88
https://doi.org/10.1136/bmjgh-2016-000260.88