Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ken-ichiro Matsunaga"'
Autor:
Ken-ichiro Matsunaga, Michiko Kimoto, Vanessa Weixun Lim, Tun-Linn Thein, Shawn Vasoo, Yee-Sin Leo, William Sun, Ichiro Hirao
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Serologic tests to detect specific IgGs to antigens related to viral infections are urgently needed for diagnostics and therapeutics. We present a diagnostic method for serotype-specific IgG identification of dengue infection by a competitiv
Externí odkaz:
https://doaj.org/article/d0eae76c6b634f2dbf403d1edf77da4c
Autor:
Vanessa Weixun Lim, Ken-ichiro Matsunaga, William Sun, Shawn Vasoo, Ichiro Hirao, Yee Sin Leo, Yu Qian Wong, Hui Pen Tan, Michiko Kimoto
Publikováno v:
Nucleic Acids Research
Genetic alphabet expansion of DNA by introducing unnatural bases (UBs), as a fifth letter, dramatically augments the affinities of DNA aptamers that bind to target proteins. To determine whether UB-containing DNA (UB-DNA) aptamers obtained by affinit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bfae5f66a522d2bfa873a78cf34b84
http://europepmc.org/articles/PMC8599795
http://europepmc.org/articles/PMC8599795
Autor:
Shoji Ando, Hitoshi Kawano, Akiko Yamamoto, Ken Ichiro Matsunaga, Toshihisa Ueda, Toshihiko Matsumoto, Toyoaki Anai
Publikováno v:
Protein & Peptide Letters. 27:432-446
Background:Intermediate Filaments (IFs) are major constituents of the cytoskeletal systems in animal cells.Objective:To gain insights into the structure-function relationship of invertebrate cytoplasmic IF proteins, we characterized an IF protein fro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df0439cc446528e189ee9bdd4fca4ec
https://doi.org/10.2174/0929866526666191025102902
https://doi.org/10.2174/0929866526666191025102902
Autor:
Ichiro Hirao, Yee Sin Leo, Ken-ichiro Matsunaga, Shawn Vasoo, Tun-Linn Thein, William Sun, Vanessa W. Lim, Michiko Kimoto
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Serologic tests to detect specific IgGs to antigens related to viral infections are urgently needed for diagnostics and therapeutics. We present a diagnostic method for serotype-specific IgG identification of dengue infection by a competitive enzyme-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a4e40defc86dd705896c62835a11b79
http://europepmc.org/articles/PMC8429655
http://europepmc.org/articles/PMC8429655
Publikováno v:
Current Protocols in Chemical Biology. 9:315-339
A novel technology, genetic alphabet expansion, has rapidly advanced through the successful creation of unnatural base pairs that function as a third base pair in replication. Recently, genetic alphabet expansion has been applied to some practical ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2996beb5b7fad1161fb7a138cc2b6ebd
https://doi.org/10.1002/cpch.31
https://doi.org/10.1002/cpch.31
Autor:
Akiko, Yamamoto, Ken-Ichiro, Matsunaga, Toyoaki, Anai, Hitoshi, Kawano, Toshihisa, Ueda, Toshihiko, Matsumoto, Shoji, Ando
Publikováno v:
Protein and peptide letters. 27(5)
Intermediate Filaments (IFs) are major constituents of the cytoskeletal systems in animal cells.To gain insights into the structure-function relationship of invertebrate cytoplasmic IF proteins, we characterized an IF protein from the platyhelminth,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7fce59ece8e055e8cc63cf120274bb8a
https://pubmed.ncbi.nlm.nih.gov/31652112
https://pubmed.ncbi.nlm.nih.gov/31652112
Publikováno v:
ACS synthetic biology. 8(6)
The creation of unnatural base pairs (UBPs) has rapidly advanced the genetic alphabet expansion technology of DNA, requiring a new sequencing method for UB-containing DNAs with five or more letters. The hydrophobic UBP, Ds-Px, exhibits high fidelity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f94507181adbad74022fca2180e88c
https://pubmed.ncbi.nlm.nih.gov/30995835
https://pubmed.ncbi.nlm.nih.gov/30995835
Publikováno v:
Journal of the American Chemical Society. 139(1)
The novel evolutionary engineering method ExSELEX (genetic alphabet expansion for systematic evolution of ligands by exponential enrichment) provides high-affinity DNA aptamers that specifically bind to target molecules, by introducing an artificial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83b961569d0111e79a66dca88e867f2a
https://pubmed.ncbi.nlm.nih.gov/27966933
https://pubmed.ncbi.nlm.nih.gov/27966933
Publikováno v:
Nature Biotechnology. 31:453-457
DNA aptamers produced with natural or modified natural nucleotides often lack the desired binding affinity and specificity to target proteins. Here we describe a method for selecting DNA aptamers containing the four natural nucleotides and an unnatur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1df3646d36f92750d8c9a3aedf4f76
https://doi.org/10.1038/nbt.2556
https://doi.org/10.1038/nbt.2556
Publikováno v:
Modified Nucleic Acids ISBN: 9783319271095
Half a century ago, Alexander Rich proposed a genetic alphabet expansion system by the creation of an artificial extra base pair, known as an unnatural base pair. Now, as an ultimate modification technology, the development of unnatural base pairs an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16e629d0fb0aa0d22e3329d29707a728
https://doi.org/10.1007/978-3-319-27111-8_12
https://doi.org/10.1007/978-3-319-27111-8_12
