Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Ken-ichiro Hiwatari"'
Autor:
Sakuma, Shinji a, ⁎, Yano, Takanori a, Masaoka, Yoshie a, Kataoka, Makoto a, Ken-ichiro Hiwatari b, Tachikawa, Hiroyuki b, Shoji, Yoshikazu b, Kimura, Ryoji b, Ma, Huaiyu c, Yang, Zhijian c, Tang, Li c, Hoffman, Robert M. c, d, Yamashita, Shinji a
Publikováno v:
In Journal of Controlled Release 2009 134(1):2-10
Publikováno v:
Bulletin of the Chemical Society of Japan. 91:563-570
The attachment of 3H-naphthopyran to a three-dimensional network of polysiloxane elastomer was carried out by hydrosilylation reactions using 3H-9-(5-hexenyloxy)naphthopyran. The photochemical coloration and subsequent thermal decoloration behaviors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2d0ce69ae13f1893b35bb0cab67a6c3
https://doi.org/10.1246/bcsj.20170396
https://doi.org/10.1246/bcsj.20170396
Autor:
Kohei Miyata, John C. Gore, Hironori Kumagai, Etsuo Tobita, Ken-ichiro Hiwatari, Kohta Mohri, Hiroshi Nakase, Wellington Pham, Kevin J. Wilson, Takuya Yoshino, Meiying Zhu, Shinji Sakuma, Tetsuya Ikejima, Kazufumi Tsubaki, Kay Washington, Takumi Fukuchi
Publikováno v:
International Journal of Nanomedicine
Hiroshi Nakase,1,2 Shinji Sakuma,3 Takumi Fukuchi,4 Takuya Yoshino,1,5 Kohta Mohri,3 Kohei Miyata,3,6 Hironori Kumagai,6 Ken-Ichiro Hiwatari,6 Kazufumi Tsubaki,6 Tetsuya Ikejima,6 Etsuo Tobita,6 Meiying Zhu,7 Kevin J Wilson,7 Kay Washington,8 John C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8ac15302637f45d8db2be9aec0e024
http://europepmc.org/articles/PMC5340240
http://europepmc.org/articles/PMC5340240
Autor:
Koichi Shigeno, Etsuo Tobita, Kozue Fujii, Satoshi Higashitarumi, Kyohei Ochiai, Kohei Miyata, Kazufumi Tsubaki, Masami Ukawa, Ken-ichiro Hiwatari, Sohei Tanishita, Shinji Sakuma, Hironori Kumagai, Kohta Mohri, Seiya Ishizaki, Mako Yamada, Hideo Kobayashi
Publikováno v:
Bioconjugate chemistry. 29(5)
Peptide and protein drugs, which are categorized as biologics, exhibit poor membrane permeability. This pharmacokinetic disadvantage has largely restricted the development of noninvasive dosage forms of biologics that deliver into systemic circulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa1612d1854d8e1947920a740ad70975
https://pubmed.ncbi.nlm.nih.gov/29648441
https://pubmed.ncbi.nlm.nih.gov/29648441
Autor:
Kyohei Ochiai, Naoki Morimoto, Sadaaki Maeda, Etsuo Tobita, Kohta Mohri, Megumi Maruyama, Ken-ichiro Hiwatari, Yuki Ishimaru, Shinji Sakuma, Kohei Miyata, Norimasa Nakamoto, Emi Hayashi, Kazufumi Tsubaki, Kengo Nagata
Publikováno v:
Bioconjugate Chemistry. 26:1782-1790
We have been investigating the potential use of cell-penetrating peptide-linked polymers as a novel penetration enhancer. Since previous in vivo studies demonstrated that poly(N-vinylacetamide-co-acrylic acid) bearing D-octaarginine, a typical cell-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67d7b7e48dad6588ecda6310481eda1a
https://doi.org/10.1021/acs.bioconjchem.5b00323
https://doi.org/10.1021/acs.bioconjchem.5b00323
Autor:
Richard McClure, Tokio Kitamura, John C. Gore, Shinji Sakuma, Kohta Mohri, Wellington Pham, Ken-ichiro Hiwatari, Etsuo Tobita, Moe Shimosato, Seiji Koike, Tetsuya Ikejima, Hironori Kumagai
Publikováno v:
Nanomedicine: Nanotechnology, Biology and Medicine. 11:1227-1236
We are investigating an imaging agent that detects early-stage primary colorectal cancer on the mucosal surface in real time under colonoscopic observation. The imaging agent, which is named the nanobeacon, is fluorescent nanospheres conjugated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f44363b06bf5143d8cac527d64afa8d
https://doi.org/10.1016/j.nano.2015.02.003
https://doi.org/10.1016/j.nano.2015.02.003
Autor:
Masanori Baba, Etsuo Tobita, Kyohei Ochiai, Naoki Morimoto, Kohta Mohri, Rikito Endo, Kazuhiro Nishida, Tomomi Egawa, Ken-ichiro Hiwatari, Tomofumi Murakami, Makoto Kataoka, Kohei Miyata, Seiji Koike, Shinji Sakuma, Tomofumi Uto, Shinji Yamashita
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 92:56-64
We evaluated cross-reactivity of immunoglobulin A (IgA) secreted on the nasal mucosa in mice that were nasally inoculated 4 times with a mixture of inactivated H1N1 influenza A viruses and poly(N-vinylacetamide-co-acrylic acid) (PNVA-co-AA) bearing d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8101cdd30fc484cd2bca6602dc3e6d5
https://doi.org/10.1016/j.ejpb.2015.02.010
https://doi.org/10.1016/j.ejpb.2015.02.010
Autor:
John C. Gore, Timothy Quang, Kevin J. Wilson, Michael Siuta, Rebecca Richards-Kortum, Alex T Holt, Ken-ichiro Hiwatari, Hironori Kumagai, Kay Washington, James Y. H. Yu, Eric Liu, Tokio Kitamura, Richard McClure, Stephanie Kao, Seiji Koike, Jalysa Erskind, Reed A. Omary, Shinji Sakuma, Wellington Pham, Etsuo Tobita
Publikováno v:
International Journal of Cancer. 136:1095-1103
Thomsen-Friedenreich (TF) antigen belongs to the mucin-type tumor-associated carbohydrate antigen. Notably, TF antigen is overexpressed in colorectal cancer (CRC) but is rarely expressed in normal colonic tissue. Increased TF antigen expression is as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c3b3961fd9013e0f8ab518e0cb8fc8c
https://doi.org/10.1002/ijc.29093
https://doi.org/10.1002/ijc.29093
Autor:
Haruki Higashino, Makoto Kataoka, Naoki Morimoto, Hironori Kumagai, John C. Gore, Etsuo Tobita, Seiji Koike, Wellington Pham, Shinji Yamashita, Shinji Sakuma, Ken-ichiro Hiwatari, Moe Shimosato, Yoshie Masaoka, Tokio Kitamura, Robert M. Hoffman
Publikováno v:
Contrast Media & Molecular Imaging. 10:135-143
We have been investigating an imaging agent that enables real-time and accurate diagnosis of early colorectal cancer at the intestinal mucosa by colonoscopy. The imaging agent is peanut agglutinin-immobilized polystyrene nanospheres with surface poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c4c1a5cf67d250900b683aa89d1aaf2
https://doi.org/10.1002/cmmi.1609
https://doi.org/10.1002/cmmi.1609
Autor:
Ken-ichiro Hiwatari, Shinji Sakuma
Publikováno v:
Drug Delivery System. 28:109-118
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a5958cd12177fc7dd14152bc0fdae79
https://doi.org/10.2745/dds.28.109
https://doi.org/10.2745/dds.28.109