Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Ken-ichi Takeuchi"'
Publikováno v:
Genes to Cells. 27:113-123
Neural functions are known to decline during normal aging and neurodegenerative diseases. However, the mechanisms of functional impairment owing to the normal aging of the brain are poorly understood. Previously, we reported that caspase-3-like prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2acb7b2cecce45a82e991107690087cb
https://doi.org/10.1111/gtc.12914
https://doi.org/10.1111/gtc.12914
Autor:
Takahiro Chihara, Aki Kitabayashi, Michie Morimoto, Ken-ichi Takeuchi, Kaoru Masuyama, Ayako Tonoki, Ronald L Davis, Jing W Wang, Masayuki Miura
Publikováno v:
PLoS Genetics, Vol 10, Iss 6, p e1004437 (2014)
Sensory and cognitive performance decline with age. Neural dysfunction caused by nerve death in senile dementia and neurodegenerative disease has been intensively studied; however, functional changes in neural circuits during the normal aging process
Externí odkaz:
https://doaj.org/article/3ce764b4760c4b11b973e1f6f954261d
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Polyunsaturated fatty acids (PUFAs) play crucial roles in adaptation to cold environments in a wide variety of animals and plants. However, the mechanisms by which PUFAs affect thermoregulatory behaviour remain elusive. Thus, we investigated the role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d105e908174de04af8d4d3cc1cdf9c0
http://europepmc.org/articles/PMC7366712
http://europepmc.org/articles/PMC7366712
Autor:
Wakae Awano, Daisuke Yamamoto, Ken Ichi Takeuchi, Masako Aizu, Shigenobu Yonemura, Yoshiro Nakano, Yasuo Mori, Masato Umeda, Utako Kato, Mizuho Kaneda, Shigeki Kiyonaka
Publikováno v:
Science. 323:1740-1743
Temperature affects the physiology, behavior, and evolution of organisms. We conducted mutagenesis and screens for mutants with altered temperature preference in Drosophila melanogaster and identified a cryophilic (cold-seeking) mutant, named atsugar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ad2e78feab4215a51e3e21597ed741
https://doi.org/10.1126/science.1165712
https://doi.org/10.1126/science.1165712
Publikováno v:
SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS. 7(6):531-535
Diamantane is a hydrocarbon whose carbon framework is a part of diamond lattices. Acylative ring expansion of 1- and 4-diamantanecarbaldehyde using benzoyl trifluoromethanesulfonate and trifluoromethanesulfonic acid yielded 10-hydroxyhomodiamant-9-yl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794f9910ba554f7700067001213a6106
http://hdl.handle.net/2433/35830
http://hdl.handle.net/2433/35830
Autor:
Tatsuro Irimura, Yoko Kawada, Ken-ichi Takeuchi, Kaoru Miyazaki, Seon Ae Han, Tsutomu Tsuji, Shinya Komatsu, Hiroto Mizushima, Mieko Kai-Murozono
Publikováno v:
Clinical and Experimental Metastasis. 19:127-134
We evaluated the role of soluble factors produced from epidermal cells in melanoma cell motility by using the Boyden chamber chemoinvasion system. The migration of two melanoma cell lines, A375 and Mewo, was potentiated by conditioned media of A431 e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58b52169732c10748ad83c7f46b01de7
https://doi.org/10.1023/a:1014573204062
https://doi.org/10.1023/a:1014573204062
Autor:
Ken-ichi Takeuchi, Birei Furuta, Makoto Itakura, Masato Umeda, Ayako Harada, Masami Takahashi
Publikováno v:
Journal of Biological Chemistry. 275:36885-36891
It has been proposed that the cortical actin filament networks act as a cortical barrier that must be reorganized to enable docking and fusion of the synaptic vesicles with the plasma membranes. We identified a novelneuron-associated developmentallyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0858e09463185dec81eb17dddc4dcb0a
https://doi.org/10.1074/jbc.m004069200
https://doi.org/10.1074/jbc.m004069200
Autor:
Tsutomu Tsuji, Wilma Puzon-McLaughlin, Atsushi Irie, Xi Ping Zhang, Ken Ichi Takeuchi, Nicholas L. Kovach, Suzanne Laferté, Nicole L. Prokopishyn, Yoshikazu Takada
Publikováno v:
Biochemistry. 38:14424-14431
Integrin/ligand interaction is a therapeutic target for many diseases. We previously reported that residues critical for ligand binding are clustered in N-terminal repeat 3 (in the predicted 2-3 loop) of alpha 4, alpha 5 and alpha IIb. Here we have l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::719681931aca08d48221ccafed2aaf11
https://doi.org/10.1021/bi990323b
https://doi.org/10.1021/bi990323b
Autor:
Tatsuro Irimura, Ken-ichi Takeuchi, Sen-itiroh Hakomori, Tsutomu Tsuji, Naoki Takahashi, Seon Ae Han
Publikováno v:
Journal of Biochemistry. 125:1183-1188
Integrin a3P1 (VLA-3) is an adhesion receptor for extracellular matrix proteins including various isoforms of laminin. We have isolated mouse genomic clones encoding the integrin a3 subunit and deduced the exon/intron organization. The mouse integrin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::446bc1ea848fb8b4eb8b67b2b44171a9
https://doi.org/10.1093/oxfordjournals.jbchem.a022402
https://doi.org/10.1093/oxfordjournals.jbchem.a022402
Autor:
Makio Takeda, Sayoko Ihara, Sigeaki Kato, Yasuhisa Fukui, Kenichi Tanaka, Hideki Fujisawa, Ken-ichi Takeuchi, Masato Umeda, Kaori Horiguchi, Toshinori Yoshida, Satoshi Nagata
Publikováno v:
Journal of Biological Chemistry. 274:3919-3922
PIP3BP is a phosphatidylinositol 3,4,5-trisphosphate-binding protein (PIP3BP) abundant in brain, containing a zinc finger motif and two pleckstrin homology (PH) domains. Staining of rat brain cells with anti-PIP3BP antibody and determination of local
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a332b2a3e47852ed3d78690fcde81f70
https://doi.org/10.1074/jbc.274.7.3919
https://doi.org/10.1074/jbc.274.7.3919