Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Ken-ichi Kariya"'
Autor:
Masato Umikawa, Kazuhide Nishihara, Fumikazu Nimura, Akira Arasaki, Tessho Maruyama, Saori Nakachi, Akira Matayoshi, Toshiyuki Nakasone, Naoki Yoshimi, Kimiko Takei, Ken-ichi Kariya
Publikováno v:
Oncology Letters
MicroRNAs (miRs) are expected to serve as prognostic tools for cancer. However, many miRs have been reported as prognostic markers of recurrence or metastasis in oral squamous cell carcinoma patients. We aimed to determine the prognostic markers in e
Autor:
Kimiko Takei, Goro Matsuzaki, Asako Umikawa, Tsuyoshi Asato, Ken-ichi Kariya, Masato Umikawa, Cheng Cheng Zhang
Publikováno v:
Biochemical and Biophysical Research Communications. 467:235-241
Monocytes and macrophages are important effectors and regulators of inflammation, and both their differentiation and activation are regulated strictly in response to environmental cues. Angiopoietin-like protein 2 (Angptl2) is a multifaceted protein,
Autor:
Xiaohao Yao, Y. Tony Ip, Ken-ichi Kariya, Junhao Mao, Lan Xu, Satoshi Kaneko, Xiaochu Chen, Theodore G. Wright, Peiyuan Lu, Mihir Rajurkar
Publikováno v:
Proceedings of the National Academy of Sciences. 108:11127-11132
The level of TGF-β/bone morphogenetic protein (BMP) signaling through Smad is tightly regulated to ensure proper embryonic patterning and homeostasis. Here we show that Smad activation by TGF-β/BMP is blocked by a highly conserved phosphorylation e
Autor:
Jeong-Seop Rhee, Oksana A. Malakhova, Nils Brose, Dong-Er Zhang, Ken-ichi Kariya, Olaf Jahn, Klaus-Armin Nave, Masato Umikawa, Sandra Goebbels, Samuel M. Young, Christian Rosenmund, Miso Mitkovski, Kalina Dimova, Hiroshi Kawabe, Michiko Takeda, Shutaro Katsurabayashi, Antje Neeb
Publikováno v:
Neuron
Scopus-Elsevier
Scopus-Elsevier
Summary Nedd4-1 is a " n euronal precursor cell e xpressed and d evelopmentally d ownregulated protein" and among the most abundant E3 ubiquitin ligases in mammalian neurons. In analyses of conventional and conditional Nedd4-1-deficient mice, we foun
Autor:
Ken-ichi Kariya, Masato Umikawa, Shogo Endo, Minoru Oshiro, Tomohiko Taguchi, Yukiko Uechi, Ryo Misaki, Kimiko Takei, Yoshito Yamashiro, Maitsetseg Bayarjargal, Tsuyoshi Asato
Publikováno v:
Biochemical and Biophysical Research Communications. 378:732-737
Rap2A, Rap2B, and Rap2C are Ras-like small G proteins. The role of their post-translational processing has not been investigated due to the lack of information on their downstream signaling. We have recently identified the Traf2- and Nck-interacting
Autor:
Hideo Nonaka, Yoshito Yamashiro, Tsuyoshi Asato, Maitsetseg Bayarjargal, Kouichi Kuninaka, Yukiko Uechi, Ken-ichi Kariya, Masato Umikawa, Tatsuo Suzuki, Minoru Oshiro, Kimiko Takei, Shogo Endo
Publikováno v:
Biochemical and Biophysical Research Communications. 377:573-578
Rap1 and Rap2 are similar Ras-like G proteins but perform distinct functions. By the affinity chromatography/mass-spectrometry approach and the yeast two-hybrid screening, we identified Misshapen/NIKs-related kinase (MINK) as a novel Rap2-interacting
Autor:
Ken-ichi Kariya, Nariko Miyara, Manabu Shinzato, Akihiro Iwamatsu, Yoshito Yamashiro, Shoichi Sawaguchi
Publikováno v:
Japanese Journal of Ophthalmology. 52:84-90
To investigate global protein expression profiles in the retinas of normal and glucocorticoid-induced ocular hypertensive rats by proteomic analysis.Ocular hypertension was induced by topical application of dexamethasone (DEX) for 4 weeks. Age-matche
Autor:
Ken-ichi Kariya, Yu-ichi Yamamoto, Shigeo Nonaka, Hiroshi Uezato, Kimiko Nonaka, Minoru Oshiro, Chojiro Kuwae
Publikováno v:
The Journal of Dermatology. 32:801-808
Bullous congenital ichthyosiform erythroderma (BCIE) is an autosomally dominant inherited disorder characterized by erythematous, erosive, and bullous skin lesions over the entire body at birth and abnormal hyperkeratosis on the palmoplantar sufaces
Autor:
Minoru Oshiro, Kiyohito Taira, Bat-Erdene Myagmar, Asako Hino, Kimiko Takei, Masato Umikawa, Tsuyoshi Asato, Ken-ichi Kariya, Hiroshi Uezato
Publikováno v:
Biochemical and Biophysical Research Communications. 329:1046-1052
Rap2 belongs to the Ras family of small GTP-binding proteins, but its specific signaling role is unclear. By yeast two-hybrid screening, we have found that the Caenorhabditis elegans ortholog of Rap2 interacts with a protein containing a Rho-GTPase-a
Autor:
Kimiko Nonaka, Minoru Oshiro, Hideo Nonaka, Keisuke Hagiwara, Hajime Arakaki, Akira Hattori, Ken-ichi Kariya, Shigeo Nonaka, Hiroshi Uezato, Tsuyoshi Asato
Publikováno v:
Journal of Medical Virology. 77:107-112
There have been no large-scale epidemiological studies of human papillomavirus (HPV) genotype distribution of common warts in Japan. A total of 213 patients with common warts (104 males and 109 females) in Japan were studied to detect HPV genotype di