Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ken-Ichiro Uwabe"'
Autor:
Kohji Nomura, Akemi Nakamura, Norito Yoshimura, Masayuki Sugimoto, Takanori Iwasaki, Midori Kojima, Kohji Hanasaki, Keita Fukao, Toru Nakano, Ken-Ichiro Uwabe, Seijiro Hara, Tadateru Hamada, Toshihiro Shinosaki, Noriyuki Naya, Keiichi Imagawa
Publikováno v:
Metabolism. 65:16-25
Objective Although peroxisome proliferator-activated receptor (PPAR) δ agonists have been shown to improve the serum lipoprotein profiles in humans, the impact of the changes in these lipoprotein profiles on atherosclerosis remains to be elucidated.
Autor:
Kenichi Higashino, Akio Kihara, Toru Nakano, Yoshito Numata, Tomoyo Yoshinaga, Shoichi Naito, Ken-Ichiro Uwabe
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0167848 (2016)
PLoS ONE
PLoS ONE
Epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells is one of the causative mechanisms of kidney fibrosis. In our study, we screened lipophilic compounds using a lipid library including approximately 200 lipids to identify those
Publikováno v:
Neuropathology. 18:179-187
Differential hybridization screening of the cDNA libraries derived from the rat facial nucleus was performed, and a number of cDNA clones were isolated and found to be upregulated after facial nerve axotomy. One of the isolated cDNA clones encoded th
Publikováno v:
Zoological Science. 15:173-181
The distribution of neurons which express the gene for the growth-associated protein, GAP-43, in the adult carp central nervous system (CNS) was studied by in situ hybridization using newly formed RNA probes for carp GAP-43 mRNA. A great number of ne
Publikováno v:
Neuropathology. 17:145-151
Retrograde degeneration of neurons following axotomy is an excellent experimental model of neurodegeneration. Using this model, molecular biological techniques have demonstrated a number of specific genes to be involved in the pathological processes
Autor:
Ken-Ichiro Uwabe, Yoshinari Gahara, Hajime Yamada, Toshihiko Miyake, Tadahisa Kitamura, Manabu Nakayama
Publikováno v:
Molecular Brain Research. 37:273-282
Cystatin C, a cysteine proteinase inhibitor, is expressed in the central nervous system (CNS) as well as many other organs of mammals. However, little is known concerning whether its expression is regulated under pathological conditions of the CNS an
Publikováno v:
Cellular Immunology. 157:144-157
C33 Ag (CD82) is a member of the transmembrane 4 superfamily (TM4SF) and an activation Ag of T-cells. Recent studies have shown that CD82 associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway. We have isolated cDNA and
Publikováno v:
Cellular Immunology. 143:298-309
To identify the cellular receptors and other cell surface molecules playing essential roles in the transmission of human T-cell leukemia virus type 1 (HTLV-1), we have been isolating monoclonal antibodies (mAbs) that are capable of inhibiting HTLV-1-
Autor:
Yoshito Numata, Akira Yamauchi, Hiroshi Takemoto, Koji Enomoto, Shoichi Naito, Jyunji Onoda, Ken-Ichiro Uwabe
Publikováno v:
Analytical biochemistry. 380(2)
The expression of recombinant proteins is a well-accepted technology, but their detection and purification often require time-consuming and complicated processes. This paper describes the development of a novel double epitope tag (GEPGDDGPSGAEGPPGPQG
Publikováno v:
The Journal of biological chemistry. 280(40)
We found that a monokine induced by interferon-γ (Mig, CXCL9), which belongs to the CXC chemokine subfamily, acts as a neurotrophic factor on PC12 cells and rat primary sympathetic neurons. PC12 cells were shown to express a single class of high aff