Zobrazeno 1 - 10
of 323
pro vyhledávání: '"Ken-Ichi Honma"'
Autor:
Daisuke Ono, Ken-ichi Honma, Christoph Schmal, Toru Takumi, Takeshi Kawamoto, Katsumi Fujimoto, Yukio Kato, Sato Honma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Clock genes Cry1 and Cry2, inhibitory components of core molecular feedback loop, are regarded as critical molecules for the circadian rhythm generation in mammals. A double knockout of Cry1 and Cry2 abolishes the circadian behavioral rhythm
Externí odkaz:
https://doaj.org/article/2264fe39e11443cc9f953c3785c8c006
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Externí odkaz:
https://doaj.org/article/62848283ffca4286869cd09843269b31
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
In mammals, the central circadian clock is located in the suprachiasmatic nucleus (SCN) of the hypothalamus. Individual SCN cells exhibit intrinsic oscillations, and their circadian period and robustness are different cell by cell in the absence of c
Externí odkaz:
https://doaj.org/article/2f5f66dd29be469e947420ca4dc5f77d
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract Circadian rhythms in clock genes, Bmal1 and Per2 expression were monitored simultaneously in the cultured slice of mouse suprachiasmatic nucleus (SCN) by dual bioluminescent reporters. In the neonatal SCN, the phase-relation between the Bmal
Externí odkaz:
https://doaj.org/article/c772267b627a443a9dc921312ec279ef
Autor:
Tomoko Yoshikawa, Natsuko F. Inagaki, Seiji Takagi, Shigeru Kuroda, Miwako Yamasaki, Masahiko Watanabe, Sato Honma, Ken-ichi Honma
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The circadian pacemaker in the suprachiasmatic nucleus (SCN) yields photoperiodic response to transfer seasonal information to physiology and behavior. To identify the precise location involved in photoperiodic response in the SCN, we analyz
Externí odkaz:
https://doaj.org/article/d6eb6c9b7d2d4b1b94f1ab7f6c5bee7a
Autor:
Christoph Schmal, Daisuke Ono, Jihwan Myung, J Patrick Pett, Sato Honma, Ken-Ichi Honma, Hanspeter Herzel, Isao T Tokuda
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 9, p e1007330 (2019)
Circadian rhythms are generated by interlocked transcriptional-translational negative feedback loops (TTFLs), the molecular process implemented within a cell. The contributions, weighting and balancing between the multiple feedback loops remain debat
Externí odkaz:
https://doaj.org/article/c4ce1bb3dd004e398f17071dcd73ed8f
Autor:
Toshiyuki Hamada, Kenneth Sutherland, Masayori Ishikawa, Naoki Miyamoto, Sato Honma, Hiroki Shirato, Ken-ichi Honma
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The circadian rhythms of peripheral clocks are difficult to study. Here the authors demonstrate a technique to image clock gene expression simultaneously in various tissues of freely moving mice, and use it to show that a long duration light pulse re
Externí odkaz:
https://doaj.org/article/513f094ca9104b80923605599407c515
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006607 (2018)
Circadian clocks are autonomous oscillators driving daily rhythms in physiology and behavior. In mammals, a network of coupled neurons in the suprachiasmatic nucleus (SCN) is entrained to environmental light-dark cycles and orchestrates the timing of
Externí odkaz:
https://doaj.org/article/3e7a276d1e854ae5a43040fe4a50fb78
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80615 (2013)
Clock genes Cryptochrome (Cry1) and Cry2 are essential for expression of circadian rhythms in mice under constant darkness (DD). However, circadian rhythms in clock gene Per1 expression or clock protein PER2 are detected in the cultured suprachiasmat
Externí odkaz:
https://doaj.org/article/6386cd0a32e8401a97a81beb17773fe0
Publikováno v:
American Journal of Physiology: Regulatory, Integrative & Comparative Physiology; Jan2024, Vol. 326 Issue 1, pR19-R28, 10p