Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ken-Edwin Aryee"'
Autor:
Richard A Morgan, David J Rawlings, Richard G James, Jasmine N Edelstein, Tyler F Hill, Michael D Leiken, Katherine M Molloy, Glory Adekanye, Caroline Bullock, Adam S Lazorchak, Ken-Edwin Aryee, Sean P Arlauckas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/e99d267b8a3846c3a680953b2c556131
Autor:
Frederick R Roberts, Clinton Hupple, Elaine Norowski, Nicole C Walsh, Natalia Przewozniak, Ken-Edwin Aryee, Filia M Van Dessel, Agata Jurczyk, David M Harlan, Dale L Greiner, Rita Bortell, Chaoxing Yang
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178641 (2017)
Studies of human cadaveric pancreas specimens indicate that pancreas inflammation plays an important role in type 1 diabetes pathogenesis. Due to the inaccessibility of pancreas in living patients, imaging technology to visualize pancreas inflammatio
Externí odkaz:
https://doaj.org/article/dcdb65ec0f2844ffb919749025c32f45
Publikováno v:
Journal of Leukocyte Biology. 113:418-433
Agents that induce inflammation have been used since the 18th century for the treatment of cancer. The inflammation induced by agents such as Toll-like receptor agonists is thought to stimulate tumor-specific immunity in patients and augment control
Enhanced development of functional human NK cells in NOD‐ scid‐IL2rg null mice expressing human IL15
Autor:
Ken‐Edwin Aryee, Lisa M. Burzenski, Li‐Chin Yao, James G. Keck, Dale L. Greiner, Leonard D. Shultz, Michael A. Brehm
Publikováno v:
The FASEB Journal. 36
Autor:
Ken-Edwin, Aryee, Lisa M, Burzenski, Li-Chin, Yao, James G, Keck, Dale L, Greiner, Leonard D, Shultz, Michael A, Brehm
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 36(9)
Human innate immunity plays a critical role in tumor surveillance and in immunoregulation within the tumor microenvironment. Natural killer (NK) cells are innate lymphoid cells that have opposing roles in the tumor microenvironment, including NK cell
Immunodeficient mice are being used as recipients of human hematopoietic stem cells (HSC) for in vivo analyses of human immune system development and function. The development of several stocks of immunodeficient Prkdc scid ( scid ), or recombination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f811aa0fac763cf5dbe5a85fc141b134
https://doi.org/10.17504/protocols.io.bu9nnz5e
https://doi.org/10.17504/protocols.io.bu9nnz5e
Autor:
Michael A. Brehm, Laurie L. Kenney, Sonal Jangalwe, Nicole C. Walsh, Ken-Edwin Aryee, Leonard D. Shultz, Dale L. Greiner
Publikováno v:
Annual Review of Pathology: Mechanisms of Disease. 12:187-215
Immunodeficient mice engrafted with functional human cells and tissues, that is, humanized mice, have become increasingly important as small, preclinical animal models for the study of human diseases. Since the description of immunodeficient mice bea
Autor:
Ronald G. Gregg, Shunyan Mo, Sonia Ortiz-Miranda, Agata Jurczyk, Leah Hennings, Scott A. Shaffer, Dale L. Greiner, Alan Cheng, Rui Ji, Rita Bortell, Terry W. Fletcher, Ann R. Rittenhouse, Ken-Edwin Aryee
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 311:G903-G919
Knockout technology has proven useful for delineating functional roles of specific genes. Here we describe and provide an explanation for striking pathology that occurs in a subset of genetically engineered mice expressing a rat CaVβ2a transgene und
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1953
A significant obstacle to the study of human cancer biology and the testing of human specific immunotherapeutics is the paucity of translational models that recapitulate both the growth of human tumors and the functionality of human immune systems. H
Publikováno v:
Target Identification and Validation in Drug Discovery ISBN: 9781493991440
A significant obstacle to the study of human cancer biology and the testing of human specific immunotherapeutics is the paucity of translational models that recapitulate both the growth of human tumors and the functionality of human immune systems. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48b5eca44f02643ac4523c2c74bb4e7d
https://doi.org/10.1007/978-1-4939-9145-7_15
https://doi.org/10.1007/978-1-4939-9145-7_15