Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ken Y. Hui"'
Autor:
Patti Hayes, Sandeep Dhillon, Kim OâNeill, Cornelia Thoeni, Ken Y. Hui, Abdul Elkadri, Conghui H. Guo, Lidija Kovacic, Gabriella Aviello, Luis A. Alvarez, Anne M. Griffiths, Scott B. Snapper, Steven R. Brant, James H. Doroshow, Mark S. Silverberg, Inga Peter, Dermot P.B. McGovern, Judy Cho, John H. Brumell, Holm H. Uhlig, Billy Bourke, Aleixo M. Muise, Ulla G. Knaus
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 489-502 (2015)
Background & Aims: Defects in intestinal innate defense systems predispose patients to inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases in the mucosal barrier ma
Externí odkaz:
https://doaj.org/article/85c1ea5cdde549e4b26d7b8563751646
Autor:
Bo Konings, Luisa G. Villatoro, Guillermo A. Barahona, Robert Burns, Megan McKnight, Ken Y. Hui, Pankaj J. Pasricha
Publikováno v:
Gastrointestinal Endoscopy. 95:AB324
Autor:
Ken Y. Hui, Qian Li, Liansheng Liu, Loyal A. Goff, Stephanie C. Hicks, Subhash Kulkarni, Pankaj J. Pasricha
Publikováno v:
Gastroenterology. 162:S-124
Autor:
Bo Konings, Luisa G. Villatoro, Guillermo A. Barahona, Robert Burns, Megan McKnight, James J. Potter, Ken Y. Hui, Gayane Yenokyan, Pankaj J. Pasricha
Publikováno v:
Gastroenterology. 162:S-108
Autor:
Bo Konings, Luisa G. Villatoro, Jef Van den Eynde, Guillermo A. Barahona, Robert Burns, Megan McKnight, Ken Y. Hui, Pankaj J. Pasricha
Publikováno v:
Gastroenterology. 162:S-196
Autor:
Todd Lencz, Talin Haritunians, Ling-Shiang Chuang, Xianting Li, Mark S. Silverberg, Seymour Katz, Jianzhong Hu, Nikolas Pontikos, Nai Yun Hsu, Nir Barzilai, Anthony W. Segal, Steven R. Brant, Shai Carmi, Philippe R Labrias, Mark J. Daly, Kyle Gettler, Adam Schaffner, Richard H. Duerr, John D. Rioux, Dermot P.B. McGovern, Haydeh Payami, Jeffery M. Vance, Ernie Chen, Nathan Pankratz, Darren Ruane, Elena R. Schiff, Susan B. Bressman, Judy H. Cho, Robert J. Desnick, Iban Ubarretxena-Belandia, Richard H. Myers, Yakov Peter, Xiuliang Bao, Yiannis A. Ioannou, Dalin Li, Gil Atzmon, William K. Scott, Eric E. Schadt, Lorraine N. Clark, Heriberto Fernandez-Hernandez, Adam P. Levine, Inga Peter, Nicole Villaverde, Adam S. Cheifetz, Itsik Pe'er, Ken Y. Hui, Zhenyu Yue, Tatiana Foroud, Harry Ostrer, Laurie J. Ozelius, Manual Rivas
Publikováno v:
Science Translational Medicine. 10
Crohn’s disease (CD), a form of inflammatory bowel disease, has a higher prevalence in Ashkenazi Jewish than in non-Jewish European populations. To define the role of nonsynonymous mutations, we performed exome sequencing of Ashkenazi Jewish patien
Autor:
Sandeep S. Dhillon, Billy Bourke, Anne M. Griffiths, Conghui H. Guo, Dermot P.B. McGovern, James H. Doroshow, Inga Peter, Luis Alvarez, Lidija Kovačič, Abdul Elkadri, Scott B. Snapper, Aleixo M. Muise, Ken Y. Hui, Judy H. Cho, Gabriella Aviello, Steven R. Brant, Cornelia Thoeni, Kim O’Neill, Holm H. Uhlig, John H. Brumell, PK Hayes, Ulla G. Knaus, Mark S. Silverberg
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 489-502 (2015)
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 489-502 (2015)
Background & Aims: Defects in intestinal innate defense systems predispose patients to inflammatory bowel disease (IBD). Reactive oxygen species (ROS) generated by nicotinamide-adenine dinucleotide phosphate (NADPH) oxidases in the mucosal barrier ma
Autor:
Bruce E. Sands, Peter Legnani, Steven R. Brant, Maria T. Abreu, Robert J. Desnick, Manuel A. Rivas, Todd Lencz, Seth Lipka, Wei Zhang, Clara Abraham, Inga Peter, Beatrice M. Bowen, James F. George, Anthony W. Segal, Jody-Ann Facey, Jacob L. McCauley, Nicole Villaverde, Arthur Mortha, Joanne M. Stempak, Dalin Li, Ellen Scherl, Lisa W. Datta, Ken Y. Hui, Sok Meng Evelyn Ng, Yashoda Sharma, L Phillip Schumm, Mark J. Daly, Romain Remark, Talin Haritunians, Elena R. Schiff, Vincent Plagnol, Sacha Gnjatic, Alexander Gusev, Heriberto Fernandez-Hernandez, Judy H. Cho, Hakon Hakonarson, Ariel Darvasi, Itsik Pe'er, Stephan R. Targan, Alexio M. Muise, Nai Yun Hsu, Adam S. Cheifetz, Gil Atzmon, Mark S. Silverberg, Ling-Shiang Chuang, Dermot P.B. McGovern, Richard H. Duerr, Nir Barzilai, Jerome I. Rotter, Kaida Ning, Miriam Merad, Kent D. Taylor, Seymour Katz, Marla J. Dubinsky, Tramy Luong, Adam P. Levine, Nikolas Pontikos, Subramaniam Kugathasan, Hongyu Zhao, Adeeb Rahman
Publikováno v:
Gastroenterology, vol 151, iss 4
Chuang, LS; Villaverde, N; Hui, KY; Mortha, A; Rahman, A; Levine, AP; et al.(2016). A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology, 151(4), 710-723.e2. doi: 10.1053/j.gastro.2016.06.045. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7s0072ck
Chuang, LS; Villaverde, N; Hui, KY; Mortha, A; Rahman, A; Levine, AP; et al.(2016). A Frameshift in CSF2RB Predominant Among Ashkenazi Jews Increases Risk for Crohn's Disease and Reduces Monocyte Signaling via GM-CSF. Gastroenterology, 151(4), 710-723.e2. doi: 10.1053/j.gastro.2016.06.045. UCLA: Retrieved from: http://www.escholarship.org/uc/item/7s0072ck
Background & Aims Crohn's disease (CD) has the highest prevalence in Ashkenazi Jewish populations. We sought to identify rare, CD-associated frameshift variants of high functional and statistical effects. Methods We performed exome sequencing and arr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be36a9d4395c549af22f254495b5dec3
https://escholarship.org/uc/item/7s0072ck
https://escholarship.org/uc/item/7s0072ck
Autor:
Ken Y, Hui, Heriberto, Fernandez-Hernandez, Jianzhong, Hu, Adam, Schaffner, Nathan, Pankratz, Nai-Yun, Hsu, Ling-Shiang, Chuang, Shai, Carmi, Nicole, Villaverde, Xianting, Li, Manual, Rivas, Adam P, Levine, Xiuliang, Bao, Philippe R, Labrias, Talin, Haritunians, Darren, Ruane, Kyle, Gettler, Ernie, Chen, Dalin, Li, Elena R, Schiff, Nikolas, Pontikos, Nir, Barzilai, Steven R, Brant, Susan, Bressman, Adam S, Cheifetz, Lorraine N, Clark, Mark J, Daly, Robert J, Desnick, Richard H, Duerr, Seymour, Katz, Todd, Lencz, Richard H, Myers, Harry, Ostrer, Laurie, Ozelius, Haydeh, Payami, Yakov, Peter, John D, Rioux, Anthony W, Segal, William K, Scott, Mark S, Silverberg, Jeffery M, Vance, Iban, Ubarretxena-Belandia, Tatiana, Foroud, Gil, Atzmon, Itsik, Pe'er, Yiannis, Ioannou, Dermot P B, McGovern, Zhenyu, Yue, Eric E, Schadt, Judy H, Cho, Inga, Peter
Publikováno v:
Science translational medicine. 10(423)
Crohn's disease (CD), a form of inflammatory bowel disease, has a higher prevalence in Ashkenazi Jewish than in non-Jewish European populations. To define the role of nonsynonymous mutations, we performed exome sequencing of Ashkenazi Jewish patients
Autor:
Raquel Milgrom, Yashoda Sharma, Leif Törkvist, Mauro D'Amato, Talin Haritunians, Ramnik J. Xavier, Hakon Hakonarson, Leonard Baidoo, Ashwin N. Ananthakrishnan, Marla Dubinsky, Graham L. Radford-Smith, Deborah D. Proctor, Mark J. Daly, Subra Kugathasan, Jan Hendrik Niess, Judy H. Cho, Jürgen Glas, L. Philip Schumm, Mark S. Silverberg, Claudio Fiocchi, Lambertus Klei, Ken Y. Hui, Miguel Regueiro, James Borneman, Dalin Li, Jonathan Braun, Steven R. Brant, Dermot P.B. McGovern, John D. Rioux, Stephan Brand, Jonas Halfvarson, Guy Aumais, Jean Paul Achkar, Lisa A. Simms, Carsten Büning, Joanne M. Stempak, Stephan R. Targan, Jonathan P. Jacobs, Richard H. Duerr, Bernie Devlin
Publikováno v:
Gastroenterology, vol 151, iss 4
Background & aimsGenome-wide association studies have identified 200 inflammatory bowel disease (IBD) loci, but the genetic architecture of Crohn's disease (CD) and ulcerative colitis remain incompletely defined. Here, we aimed to identify novel asso