Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Ken Uekawa"'
Autor:
Ken Uekawa, Yorito Hattori, Sung Ji Ahn, James Seo, Nicole Casey, Antoine Anfray, Ping Zhou, Wenjie Luo, Josef Anrather, Laibaik Park, Costantino Iadecola
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-20 (2023)
Abstract Background Cerebral amyloid angiopathy (CAA) is a devastating condition common in patients with Alzheimer’s disease but also observed in the general population. Vascular oxidative stress and neurovascular dysfunction have been implicated i
Externí odkaz:
https://doaj.org/article/0db3ad1ed089430da35a299993490c10
Autor:
Ken Uekawa, Yorito Hattori, Sung Ji Ahn, James Seo, Nicole Casey, Antoine Anfray, Ping Zhou, Wenjie Luo, Josef Anrather, Laibaik Park, Costantino Iadecola
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/6a7e233fb3564401a8c6e1131dbdcf2d
Autor:
Yuhei Suzuki, Yasuyuki Kaku, Takaho Tokuda, Ryo Takashima, Yusuke Morikawa, Toshihiro Amadatsu, Ken Uekawa, Akitake Mukasa, Shigeo Yamashiro
Publikováno v:
Interdisciplinary Neurosurgery, Vol 24, Iss , Pp 101021- (2021)
A 36-year-old male suffered from a sudden headache. Computed tomography (CT) showed a subarachnoid hemorrhage (SAH). CT angiography demonstrated an aneurysm arising from the duplicate origin of the right posterior communicating artery (PcomA). The an
Externí odkaz:
https://doaj.org/article/3659b9af45c14c2b9b57c71a7db3760a
Autor:
Hiroaki Matsuzaki, Yoshihiro Komohara, Hiromu Yano, Yukio Fujiwara, Keitaro Kai, Rin Yamada, Daiki Yoshii, Ken Uekawa, Naoki Shinojima, Yoshiki Mikami, Akitake Mukasa
Publikováno v:
Microbiology and Immunology. 67:90-98
Although pituitary endocrine tumors (PitNETs) are usually benign, some are highly invasive and recurrent. Recurrent PitNETs are often treatment-resistant and there is currently no effective evidence-based treatment. Tumor-associated macrophages (TAMs
Apoε4 disrupts neurovascular regulation and undermines white matter integrity and cognitive function
Autor:
Kenzo Koizumi, Yorito Hattori, Sung Ji Ahn, Izaskun Buendia, Antonio Ciacciarelli, Ken Uekawa, Gang Wang, Abigail Hiller, Lingzhi Zhao, Henning U. Voss, Steven M. Paul, Chris Schaffer, Laibaik Park, Costantino Iadecola
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
ApoE4 is a risk factor for small vessel disease, which can lead to cognitive impairment. Here the authors assess the microvasculature of the corpus callosum using 3-photon microscopy and find that mice expressing the ApoE4 allele are more susceptible
Externí odkaz:
https://doaj.org/article/2ab1466f234d4ba0b18f5463e1f09a16
Autor:
Naoki Shinojima, Kazutaka Ozono, Haruaki Yamamoto, Sakiko Abe, Rumi Sasaki, Yusuke Tomita, Azusa Kai, Ryosuke Mori, Takahiro Yamamoto, Ken Uekawa, Hirotaka Matsui, Kisato Nosaka, Hiroaki Matsuzaki, Yoshihiro Komohara, Yoshiki Mikami, Akitake Mukasa
Publikováno v:
Brain Tumor Pathology.
Chordoma is a rare malignant bone tumor arising from notochordal tissue. Conventional treatments, such as radical resection and high-dose irradiation, frequently fail to control the tumor, resulting in recurrence and re-growth. In this study, genetic
Autor:
An Murai, Naoki Shinojima, Genki Ikuta, Kazutaka Ozono, Yutaka Ueda, Hiroyo Mabe, Kenji Nakamura, Naoko Iwata, Haruki Fujisawa, Fusa Nagamatsu, Nagisa Komatsu, Ken Uekawa, Shigeyuki Nishikawa, Kimitoshi Nakamura, Yoshiki Mikami, Atsushi Suzuki, Yoshihisa Sugimura, Akitake Mukasa
Publikováno v:
Endocrine Journal.
Autor:
Yukio Fujiwara, Tadashi Hamasaki, Takahiro Yamamoto, Kazutaka Ohta, Naoki Shinojima, Ken Uekawa, Tatsuya Takezaki, Yoshihiro Komohara, Keitaro Kai, Shigeyuki Esumi, Akitake Mukasa, Jun-ichiro Kuroda
Publikováno v:
Human Cell. 35:226-237
Glioblastoma is a glioma characterized by highly malignant features. Numerous studies conducted on the relationship between glioblastoma and the microenvironment have indicated the significance of tumor-associated macrophages/microglia (TAMs) in glio
Autor:
Atsushi Tachibana, Sadato Akahori, Ken Uekawa, Toshihiro Amadatsu, Mizuki Takei, Shigeo Yamashiro, Masatomo Kaji, Shuichiro Okumura, Toru Nishi
Publikováno v:
Neurologia medico-chirurgica
Subarachnoid hemorrhage (SAH) is a serious cerebrovascular disease with a high mortality rate and is known as a disease that is hard to diagnose because it may be overlooked by noncontrast computed tomography (NCCT) examinations that are most frequen
Autor:
Ken Uekawa, Kenzo Koizumi, Jason Hwang, Nathalie Brunier, Yorito Hattori, Ping Zhou, Laibaik Park
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163329 (2016)
Hypercapnia induces potent vasodilation in the cerebral circulation. Although it has long been known that prostanoids participate in the cerebrovascular effects of hypercapnia, the role of prostaglandin E2 (PGE2) and PGE2 receptors have not been full
Externí odkaz:
https://doaj.org/article/8b5bd8f0c5354efc8c0a7a14847b3ed5