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Akademický článek

WT1 PEPTIDE VACCINATION IN COMBINATION WITH IMATINIB THERAPY FOR A PATIENT WITH CML IN THE CHRONIC PHASE

Autor: Miwako Narita, Masayoshi Masuko, Tohri Kurasaki, Toshiki Kitajima, Shoko Takenouchi, Anri Saitoh, Norihiro Watanabe, Tatsuo Furukawa, Ken Toba, Ichiro Fuse, Yoshifusa Aizawa, Manabu Kawakami, Yoshihiro Oka, Haruo Sugiyama, Masuhiro Takahashi

Publikováno v: International Journal of Medical Sciences, Vol 7, Iss 2, Pp 72-81 (2010)

Although tyrosine kinase inhibitors is effective for dramatically reducing CML cells, it might be difficult to eradicate completely the CML stem cells. We aimed to clarify the safety and effects of WT1 peptide vaccination in combination with imatinib

Externí odkaz: https://doaj.org/article/b23ec51d1b2e4926bef1b97d74e63ab2

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Low-Dose Erythropoietin in Patients With ST-Segment Elevation Myocardial Infarction (EPO-AMI-II) ― A Randomized Controlled Clinical Trial ―

Autor: Ken Toba, Daisaku Nakatani, Yoshio Ishida, Shungo Hikoso, Shuichiro Higo, Kiminori Kato, Kouji Yamamoto, Yasushi Fujio, Issei Komuro, Masaaki Okutsu, Hiroshi Suzuki, Yoshifusa Aizawa, Tetsuo Minamino, Ryo Araki, Takuya Ozawa, Epo-Ami-Ii study investigators, Takahisa Yamada

Publikováno v: Circulation Journal. 82:1083-1091

BACKGROUND Erythropoietin (EPO) has antiapoptotic and tissue-protective effects, but previous clinical studies using high-dose EPO have not shown cardioprotective effects, probably because of platelet activation and a lack of knowledge regarding the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c937f0dd44065cc4370a3a5f99a59d
https://doi.org/10.1253/circj.cj-17-0889

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Long-term PT-INR levels and the clinical events in the patients with non-valvular atrial fibrillation: A special reference to low-intensity warfarin therapy

Autor: Koichi Fuse, Akira Yamashina, Minoru Takahashi, Yoshio Ikeda, Masayuki Goto, Ken Takarada, Masaaki Okabe, Hitoshi Kitazawa, Atsushi Saito, Yoshifusa Aizawa, Ken Toba, Hirooki Matsushita, Hiroshi Abe, Satoru Fujita, Takeo Oguro, Masahito Sato

Publikováno v: Journal of Cardiology. 64(2):127-132

BackgroundAnticoagulation therapy is essential in atrial fibrillation (AF), and in Japan, less intense control is popular.PurposeTo assess the efficacy and safety with a special reference to low intensity warfarin therapy.Subjects and methodsIn 488 o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::287892f64259be3098a62428eab159e2

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Involvement of cross-linked ribosomal protein S19 oligomers and C5a receptor in definitive erythropoiesis

Autor: Jun Chen, Tetsuro Yamamoto, Umeko Semba, Masato Oda, Shinichiro Hattori, Seiji Okada, Rui Zhao, Tomoyasu Suzuki, Ken Toba

Publikováno v: Experimental and Molecular Pathology. 95:364-375

We performed a series of experiments under a working hypothesis that cross-linked oligomers of ribosomal protein S19 (RP S19) play an essential role in definitive erythropoiesis as a ligand of the C5a receptor of erythroblasts and macrophages. We fou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc129bdfa4cf35f9bc9022d773607f03
https://doi.org/10.1016/j.yexmp.2013.10.010

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Successful Treatment of Severe Newly Diagnosed Immune Thrombocytopenia Involving an Alveolar Hemorrhage with Combination Therapy Consisting of Romiplostim, Rituximab and Vincristine

Autor: Masato Moriyama, Shukuko Miyakoshi, Ken Toba, Jun Takizawa, Yuji Matsuo, Yasuhiko Shibasaki, Tatsuo Furukawa, Ichiro Fuse, Kiyoshi Okazuka, Kyoko Fuse, Masayoshi Masuko, Tomoyuki Tanaka, Takashi Kozakai, Hironori Kobayashi

Publikováno v: Internal Medicine. 52:1239-1242

A 51-year-old man was admitted due to a severe bleeding tendency. After he was diagnosed with immune thrombocytopenia (ITP), several therapies, including steroids, steroid pulse, vincristine and rituximab, were administered; however, the patient's bl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc8f49980313a9dcdb526b71181a1c4
https://doi.org/10.2169/internalmedicine.52.0080

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Japanese case of Budd-Chiari syndrome due to hepatic vein thrombosis successfully treated with liver transplantation

Autor: Koushi Oseki, Yutaka Aoyagi, Minoru Nomoto, Hirokazu Kawai, Yoshinobu Sato, Ken Toba, Katsuyoshi Hatakeyama, Kazuhiko Shioji, Kenji Suzuki, Tomohiro Iwasaki, Satoshi Yamamoto, Tadayuki Togashi

Publikováno v: Hepatology Research. 42:213-218

A 22-year-old Japanese woman was found to have severe esophageal varices and then suffered from hepatic encephalopathy. She was diagnosed with Budd-Chiari syndrome (BCS) due to hepatic vein (HV) thrombosis accompanied by portal vein thrombosis withou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b59af6de20fb3c2ee90140ca8018b3b5
https://doi.org/10.1111/j.1872-034x.2011.00913.x

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Kinetics of pDCs, mDCs, γδT cells and regulatory T cells in association with graft versus host disease after hematopoietic stem cell transplantation

Autor: Akie Yamahira, Miwako Narita, Masahide Takahashi, Ken Toba, Takeshi Nakamura, Y. Aizawa, Tatsuo Furukawa, Ichiro Fuse, Norihiro Watanabe, Masayoshi Masuko

Publikováno v: International Journal of Laboratory Hematology. 33:378-390

SUMMARY Introduction: Although the roles of each low-frequency immunocom- petent cells such as dendritic cells (DCs), cdT cells, and Treg cells in induction of acute or chronic graft versus host disease (GVHD) have been discussed in several reports,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7ae458aa7fbb608d4ef829ea75e0b2f6
https://doi.org/10.1111/j.1751-553x.2011.01300.x

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Hypocellularity and insufficient expression of angiogenic factors in implanted autologous bone marrow in patients with chronic critical limb ischemia

Autor: Haruo Hanawa, Ken Toba, Takao Yanagawa, Hironori Kobayashi, Masayoshi Masuko, Masato Oda, Yoshifusa Aizawa, Tsugumi Takayama, Kiminori Kato, Takuya Ozawa, Tomoyasu Suzuki, Noboru Ikarashi

Publikováno v: Heart and Vessels. 27:38-45

The aim of this study was to identify the clinical parameters of absolutely poor-prognosis patients with chronic critical limb ischemia (AP-CLI). Sixteen no-option CLI patients with arteriosclerosis obliterans: ASO (nine) and non-ASO patients (seven)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2f9185d9c9d5a8808456d7276a8bd0
https://doi.org/10.1007/s00380-011-0125-5

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