Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ken Skidmore"'
Autor:
Peter Schmieder, Ryan M. Evans, Robert G. Brinson, Chad W. Lawrence, Kristian Schweimer, Yves Aubin, Ping Xu, Göran Widmalm, Andreas Blomgren, Hamish G. Grant, Anthony J. Kearsley, John P. Marino, Janez Plavec, John B. Jordan, Geneviève Gingras, Scott A. Bradley, Koichi Kato, Stuart Parnham, Patrick N. Reardon, John R. Cort, David W. Keizer, Edward R. Zartler, Feng Ni, Frank Delaglio, Gregor Ilc, Saeko Yanaka, David A. Keire, Jonas Ståhle, Mats Wikström, Luke W. Arbogast, Alfred Ross, Thea Suter-Stahel, Darón I. Freedberg, Ana Carolina de Mattos Zeri, Maurício L. Sforça, Nils Trieloff, Desiree Tsao, Torgny Rundlöf, Xinying Jia, Kang Chen, Ken Skidmore, Gregory K. Pierens, Houman Ghasriani, Donna M. Baldisseri, Carlos A. Amezcua, Mehdi Mobli, Julie Yu Wei, Christina M. Szabo, Gerhard Wider
Publikováno v:
mAbs
The increased interest in using monoclonal antibodies (mAbs) as a platform for biopharmaceuticals has led to the need for new analytical techniques that can precisely assess physicochemical properties of these large and very complex drugs for the pur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f183bde956423f5930af0c3d9a27c283
https://nrc-publications.canada.ca/eng/view/object/?id=633c08c1-47ae-47b0-a883-a615bb5663ce
https://nrc-publications.canada.ca/eng/view/object/?id=633c08c1-47ae-47b0-a883-a615bb5663ce
Autor:
Junyan Ji, Yung-Hsiang Kao, Ming Lei, Diane Beane, Jimmy Sugahara, Christopher Cornell, Daniel P. Hewitt, Ken Skidmore
Publikováno v:
Biotechnology Progress. 29:1503-1511
Polysorbate 20 (PS-20) is often included in the formulation for therapeutic proteins to reduce protein aggregation and surface adsorption. During the production process of therapeutic proteins, various membrane filters are used to filter product pool
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::492ee23025110e4417d9260aa5bf995a
https://doi.org/10.1002/btpr.1824
https://doi.org/10.1002/btpr.1824
Publikováno v:
Biotechnology progress. 32(3)
Quantifying the clearance of extractables and leachables (E/L) throughout ultrafiltration/diafiltration (UFDF) operations allows for greater flexibility in the implementation of single-use technologies in steps upstream of the UFDF process. A proof-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69289d52de8d44073d278c062915b839
https://pubmed.ncbi.nlm.nih.gov/27071939
https://pubmed.ncbi.nlm.nih.gov/27071939
Autor:
and Ursula Simonis, Kate Aubrecht, Alicia Rene Tipton, Reneé A. Watson, Cynthia J. Norvell, Marlys J. M. Nesset, Richard Koerner, Larry M. Mink, R. Andrew Barber, Xiao Dong Ding, Joshua L. Wright, Ken Skidmore, F. Ann Walker
Publikováno v:
Inorganic Chemistry. 37:733-745
To obtain a better understanding of the effects of ortho-halogen and related substituents on the phenyl rings of TPPH2 and (TPP)Fe(III) complexes, a series of unsymmetrically substituted tetraphenylporphyrins have been synthesized. In each of these c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de4067c572607ca6bffd5e0c7d3a55ef
https://doi.org/10.1021/ic970989z
https://doi.org/10.1021/ic970989z
Autor:
Ming, Lei, Jimmy, Sugahara, Daniel, Hewitt, Diane, Beane, Rohit, Jayakar, Christopher, Cornell, Ken, Skidmore, Yung-Hsiang, Kao, Junyan, Ji
Publikováno v:
Biotechnology progress. 29(6)
Polysorbate 20 (PS-20) is often included in the formulation for therapeutic proteins to reduce protein aggregation and surface adsorption. During the production process of therapeutic proteins, various membrane filters are used to filter product pool
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ef0d653c7656c08adaaa39cc74a1ef23
https://pubmed.ncbi.nlm.nih.gov/24124005
https://pubmed.ncbi.nlm.nih.gov/24124005
Autor:
Yan Chen, Jeffrey Gorrell, Christopher Cornell, Fredric S. Jacobson, Timothy Tully, Ken Skidmore, Matthew Hutchinson, Katherine Cumnock
Publikováno v:
Bioconjugate chemistry. 24(7)
Antibody-drug conjugates (ADCs) utilizing cysteine-directed linker chemistry have cytotoxic drugs covalently bound to native heavy-heavy and heavy-light interchain disulfide bonds. The manufacture of these ADCs involves a reduction step followed by a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01892fdd36f6f66531611a4e2a1f6c5c
https://pubmed.ncbi.nlm.nih.gov/23713462
https://pubmed.ncbi.nlm.nih.gov/23713462
Publikováno v:
Biotechnology progress. 28(6)
The ability to detect and quantitate a variety of components in solution has become increasingly important in carrying out efficient and rigorous validation studies for biopharmaceutical manufacturing processes. Here, we demonstrate the general appli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::356148b272827de57ac14362a30e94f4
https://pubmed.ncbi.nlm.nih.gov/22915490
https://pubmed.ncbi.nlm.nih.gov/22915490
Autor:
Ming Lei, Jimmy Sugahara, Daniel Hewitt, Rohit Jayakar, Diane Beane, Christopher Cornell, Ken Skidmore, Yung-Hsiang Kao, Junyan Ji
Publikováno v:
Biotechnology Progress. 30:765-765
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30cd17ca91c01e1288bee637682c1461
https://doi.org/10.1002/btpr.1913
https://doi.org/10.1002/btpr.1913
Autor:
Ken Skidmore, Ursula Simonis
Publikováno v:
Inorganic Chemistry. 35:7470-7471
In an attempt to unambiguously assign all hyperfine shifts, pulsed-field gradient and nongradient 1H−13C heteronuclear multiple-bond correlation (HMBC) maps of the bis(N-methylimidazole) complex of (5-(o-nitrophenyl)-10,15,20-triphenylporphyrinato)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d5b0979e62e7a39dbff5d583995e583
https://doi.org/10.1021/ic960797o
https://doi.org/10.1021/ic960797o
Autor:
Ken Skidmore
Publikováno v:
Hospital topics. 59(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f061010dc1359d53c79d27baeea4a876
https://pubmed.ncbi.nlm.nih.gov/10250662
https://pubmed.ncbi.nlm.nih.gov/10250662