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pro vyhledávání: '"Ken Rehder"'
Autor:
Kwan Leung, Ken Rehder, Xiaofen Li, Bob Jiang, Marie Nguyen, Timothy A. Marquart, Nancy Chu, Victoria Y. Maydanik, David Lustig, Kevin D. Shenk, Yuan Li, Elfatih Elzein, Reina Natero, Daniel Soohoo, Prabha Ibrahim, Jeff Zablocki, Suresh S. Kerwar, Dmitry Koltun, Jia Hao, Dewan Zeng
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 14:6017-6021
New inhibitors of palmitoyl-CoA oxidation are based on the introduction of nitrogen heterocycles in the ‘Western Portion’ of the molecule. SAR studies led to the discovery of CVT-4325 (shown), a potent FOXi (IC50 = 380 nM rat mitochondria) with f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b80324da80b70144f2e62fa211bc8e33
https://doi.org/10.1016/j.bmcl.2004.09.077
https://doi.org/10.1016/j.bmcl.2004.09.077
