Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ken Patrene"'
Autor:
Harry C. Blair, Dean Sheppard, Ken Patrene, Verónica García-Palacios, Sun Jin Choi, Ganwei Lu, Jolene J. Windle, Hiroshi Kajiya, Noriyoshi Kurihara, G. David Roodman, Hongwei Rao, Judy Anderson
Publikováno v:
Journal of Bone and Mineral Research. 21:1657-1665
We identified a previously unknown integrin, alpha(9)beta(1), on OCLs and their precursors. Antibody to alpha(9) inhibited OCL formation in human marrow cultures, and OCLs from alpha(9) knockout mice had a defect in actin ring reorganization and an i
Autor:
Abhay, Gokhale, Jean-Claude, Rwigema, Michael W, Epperly, Julie, Glowacki, Hong, Wang, Peter, Wipf, Julie P, Goff, Tracy, Dixon, Ken, Patrene, Joel S, Greenberger
Publikováno v:
In vivo (Athens, Greece). 24(4)
We studied radioprotection and mitigation by mitochondrial-targeted Tempol (GS-nitroxide, JP4-039), in a mouse injury/irradiation model of combined injury (fracture/irradiation). Right hind legs of control C57BL/6NHsd female mice, mice pretreated wit
Autor:
Juan Li, Alfred B. Bahnson, Ying Fei, Toya Ohashi, Mark A. Kimak, Paul D. Robbins, Fu-Sheng Wei, Shelly Clark, Ken Patrene, John A. Barranger, Lorrie Lucht, Jing-Fang Wei, Sallie S. Boggs, Huiling He, Patricia Mowery-Rushton
Publikováno v:
Proceedings of the National Academy of Sciences. 89:11332-11336
A recombinant retroviral vector (MFG-GC) was used to study the efficiency of transduction of the human gene encoding glucocerebrosidase (GC; D-glucosyl-N-acylsphingosine glucohydrolase, EC 3.2.1.45), in mouse hematopoietic stem cells and expression i
Publikováno v:
Gene therapy. 4(3)
We have been developing both local and systemic gene therapy approaches to treat inflammatory and autoimmune diseases. To determine if systemic, constitutive expression of biologically active anti-inflammatory agents is therapeutic and/or has associa
Autor:
Marco Peronaci, Gaetano Donofrio, Mirca Lazzaretti, Ken Patrene, Cristina Mancini, Denise Toscani, Antonino Neri, Luca Agnelli, Martine Amiot, Marina Bolzoni, Judith L. Anderson, Simona Colla, Eugenia Martella, G. David Roodman, Daniela Guasco, Franco Aversa, Nicola Giuliani, Paola Storti, Irma Airoldi
Publikováno v:
Blood. 120:2947-2947
Abstract 2947 It has been previously reported that bone marrow (BM) microenvironment is hypoxic in multiple myeloma (MM) patients and that hypoxia inducible factor (HIF)-1α is overexpressed by MM cells. However, the potential role of HIF-1α as a th
Autor:
Paul D. Robbins, Sallie S. Boggs, Laurence Zitvogel, Hideaki Tahara, Alfred B. Bahnson, John A. Barranger, J Galea-Lauri, Gunhild M. Mueller, Christopher H. Evans, Greg Hung, Michael T. Lotze, Toya Ohashi, Ken Patrene
Publikováno v:
Annals of the New York Academy of Sciences. 716(1 Gene)
Autor:
Peter Wipf, Ken Patrene, Julie Glowackie, Joel S. Greenberger, Hong Wang, Abhay S. Gokhale, Jean-Claude M. Rwigema, Michael W. Epperly, Tracy Dixon
Publikováno v:
Cancer Research. 70:1404-1404
In the case of a nuclear explosion, combined injuries will result from radiation dispersal resulting in burns and cellular damage as well as a concussion wave resulting in traumatic bone fractures. Currently no available drugs are available to protec
Autor:
Julie Glowacki, Abhay S. Gokhale, G. David Roodman, Ken Patrene, Jean-Claude M. Rwigema, Peter Wipf, Tracy Dixon, Joel S. Greenberger
Publikováno v:
Blood. 114:4576-4576
Abstract 4576 In the case of a nuclear explosion, combined injuries may include ionizing irradiation and bone fracture. We evaluated the potential bone wound healing stimulation capacity of a new mitochondrial targeted nitroxide - JP4-039 - that was
Autor:
Peter Wipf, Abhay S. Gokhale, Glowacki Julianne, Ken Patrene, Joel S. Greenberger, Michael W. Epperly, Tracy Dixon, Hong Wang
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 75:S551
Autor:
Ken Patrene, Veronica Garcia Palacios, Judy Anderson, Chang Sook Hong, Flavi a Esteve, Alissa Huston, David Roodman
Publikováno v:
Blood. 112:2752-2752
Lytic bone lesions in patients with MM rarely heal even when patients are in complete remission for long periods of time. The mechanism behind this prolonged suppression of osteoblast activity is yet to be elucidated, and when or whether the osteobla