Zobrazeno 1 - 10 of 26 pro vyhledávání: '"Ken Onitsuka"'
1
Akademický článek
The overexpression of Twinkle helicase ameliorates the progression of cardiac fibrosis and heart failure in pressure overload model in mice.
Autor: Atsushi Tanaka, Tomomi Ide, Takeo Fujino, Ken Onitsuka, Masataka Ikeda, Takako Takehara, Yuko Hata, Emil Ylikallio, Henna Tyynismaa, Anu Suomalainen, Kenji Sunagawa
Publikováno v: PLoS ONE, Vol 8, Iss 6, p e67642 (2013)
Myocardial mitochondrial DNA (mtDNA) copy number decreases in heart failure. In post-myocardial infarction mice, increasing mtDNA copy number by overexpressing mitochondrial transcription factor attenuates mtDNA deficiency and ameliorates pathologica
Externí odkaz: https://doaj.org/article/227f0dfbabc440eba3c453847b1c3aff
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2
Early treatment with a sodium-glucose co-transporter 2 inhibitor in high-risk patients with acute heart failure: Rationale for and design of the EMPA-AHF trial
Autor: Yu, Horiuchi, Yuya, Matsue, Kazutaka, Nogi, Ken, Onitsuka, Takahiro, Okumura, Masahiro, Hoshino, Tatsuhiro, Shibata, Daisuke, Nitta, Kazuki, Yoshida, Shuntaro, Sato, Kevin, Damman, Adriaan A, Voors, Takeshi, Kitai
Publikováno v: American Heart Journal. 257:85-92
The aim of the EMPA-AHF trial is to clarify whether early initiation of a sodium-glucose co-transporter 2 inhibitor before clinical stabilization is safe and beneficial for patients with acute heart failure (AHF) who are at a high risk of adverse eve
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7507461db3e3bb345e438972b2e915
https://doi.org/10.1016/j.ahj.2022.12.005
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3
Prognostic Value of Neurological Status on Hospital Arrival for Short-Term Outcome in Patients With Cardiovascular Shock - Sub-analysis of the Japanese Circulation Society Cardiovascular Shock Registry
Autor: Yasushi Ueki, Masahiro Mohri, Rei Fukuhara, Tetsuya Matoba, Toshiaki Kadokami, Naohiro Yonemoto, Satoru Suwa, Yohei Hokama, Ken Onitsuka, Tsukasa Yagi, Nobuhiro Tanaka, Eizo Tachibana, Ken Nagao, Hiroshi Takahashi
Publikováno v: Circulation journal : official journal of the Japanese Circulation Society. 83(6)
BACKGROUND Consciousness disturbance is one of the major clinical signs associated with shock state, but its prognostic value has not been previously evaluated in cardiovascular shock patients. We aimed to evaluate the prognostic value of neurologica
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1534ae395904f4a73cfa18b1de298a
https://pubmed.ncbi.nlm.nih.gov/30944275
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4
Inoperable Primary Ovarian Carcinoid Led to the Progression of Carcinoid Heart Disease From Right-Sided to Both-Sided Involvement
Autor: Kenji Miyata, Ken Onitsuka, Hideo Yamamoto, Koji Ito, Tomonori Tadokoro, Shunsuke Katsuki, Masahiro Mohri, Takakazu Sasaguri, Atsuhiro Nakashima
Publikováno v: Circulation: Heart Failure. 10
A 73-year-old woman presented with diarrhea, leg edema, and exertional dyspnea. Six years before admission, she had been hospitalized for heart failure with moderate-to-severe tricuspid regurgitation because of incomplete leaflet coaptation (Figure 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aec0ff5d76a3a226a884192340da5683
https://doi.org/10.1161/circheartfailure.116.003719
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5
Cardiac phase-targeted dynamic load on left ventricle differentially regulates phase-sensitive gene expressions and pathway activation
Autor: Kazuo Sakamoto, Shinobu Arai, Ken Onitsuka, Yoshinori Murayama, Yuko Hata, Kazuya Hosokawa, Kenji Sunagawa, Tomomi Ide, Tomoyuki Tobushi, Takafumi Sakamoto, Takeo Fujino
Publikováno v: Journal of Molecular and Cellular Cardiology. 64:30-38
The heart has remarkable capacity to adapt to mechanical load and to dramatically change its phenotype. The mechanism underlying such diverse phenotypic adaptations remains unknown. Since systolic overload induces wall thickening, while diastolic ove
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4600b5d3b14e98201b58835ef426ae6
https://doi.org/10.1016/j.yjmcc.2013.08.008
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8
Changes in vascular properties, not ventricular properties, predominantly contribute to baroreflex regulation of arterial pressure
Autor: Yoshinori Murayama, Takamori Kakino, Atsushi Tanaka, Kazuya Hosokawa, Kenji Sunagawa, Ken Onitsuka, Kazuo Sakamoto, Takafumi Sakamoto, Tomoyuki Tobushi, Tomomi Ide, Keita Saku, Takaki Tsutsumi
Publikováno v: American journal of physiology. Heart and circulatory physiology. 308(1)
Baroreflex modulates both the ventricular and vascular properties and stabilizes arterial pressure (AP). However, how changes in those mechanical properties quantitatively impact the dynamic AP regulation remains unknown. We developed a framework of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae570ecf4db36d82830be491ca02dd0
https://pubmed.ncbi.nlm.nih.gov/25362137
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