Zobrazeno 1 - 2
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pro vyhledávání: '"Ken Nunettsu Asaba"'
Autor:
Ken Nunettsu Asaba, Keiichi Okimura, Yohei Adachi, Kazuyuki Tokumaru, Yasufumi Goto, Shigeo Fujii, Akira Watanabe, Chizuka Sakai, Eri Sakurada, Kazutoshi Amikura, Takumi Aoki
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 82:129155
Autor:
Goto Yasufumi, Kazuyuki Tokumaru, Takumi Aoki, Akira Watanabe, Yohei Adachi, Ken Nunettsu Asaba
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 41:127996
We report the discovery of a novel series of 1,5-bisphenylpyrazoles as potent MALT1 inhibitors. Structure–activity relationship exploration of a hit compound led to a potent MALT1 inhibitor. Compound 33 showed strong activity against MALT1 (IC50: 0