Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Ken Mills"'
Publikováno v:
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract The Philadelphia negative myeloproliferative neoplasms (MPN) compromise a heterogeneous group of clonal myeloid stem cell disorders comprising polycythaemia vera, essential thrombocythaemia and primary myelofibrosis. Despite distinct clinica
Externí odkaz:
https://doaj.org/article/e74e2a46bd8c46faaca97b7443183326
Autor:
Mark A. Catherwood, Dorte Wren, Laura Chiecchio, Doriane Cavalieri, David Donaldson, Sarah Lawless, Ezzat ElHassadi, Amjad Hayat, Mary R. Cahill, Derville O’Shea, Jeremy Sargent, Peter Stewart, Manisha Maurya, John Quinn, Philip Murphy, David Gonzalez de Castro, Ken Mills, Nicholas C. P. Cross, Francesco Forconi, Sunil Iyengar, Anna Schuh, Patrick Thornton
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Limited data exists to show the correlation of (tumour protein 53) TP53 mutation detected by Next generation sequencing (NGS) and the presence/absence of deletions of 17p13 detected by FISH. The study which is the largest series to date includes 2332
Externí odkaz:
https://doaj.org/article/f68447793d1e43bead15fecab502e322
Autor:
Lindsay Broadbent, Connor G. G. Bamford, Guillermo Lopez Campos, Sheerien Manzoor, David Courtney, Ahlam Ali, Olivier Touzelet, Conall McCaughey, Ken Mills, Ultan F. Power
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the coronavirus disease-19 (COVID-19) pandemic, was identified in late 2019 and caused >5 million deaths by February 2022. To date, targeted antiviral interventions against CO
Externí odkaz:
https://doaj.org/article/4820500485534bfd92cf98d195b99d42
Autor:
Blánaid M. Hicks, John Busby, Ken Mills, Francis A. O’Neil, Stuart A. McIntosh, Shu-Dong Zhang, Fabio Giuseppe Liberante, Chris R. Cardwell
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Many antipsychotics elevate prolactin, a hormone implicated in breast cancer aetiology however no studies have investigated antipsychotic use in patients with breast cancer. This study investigated if antipsychotic use is associat
Externí odkaz:
https://doaj.org/article/9ff8bc7343754e999d071091598c0e07
Publikováno v:
Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-16 (2018)
Abstract The myeloproliferative neoplasms (MPN), polycythaemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) are linked by a propensity to thrombosis formation and a risk of leukaemic transformation. Activation of cytokine
Externí odkaz:
https://doaj.org/article/dc41c89551f0434699f0286d15580696
Autor:
Connor G. G. Bamford, Lindsay Broadbent, Elihu Aranday-Cortes, Mary McCabe, James McKenna, David G. Courtney, Olivier Touzelet, Ahlam Ali, Grace Roberts, Guillermo Lopez Campos, David Simpson, Conall McCaughey, Derek Fairley, Ken Mills, Ultan F. Power, on behalf of the Breathing Together Investigators
Publikováno v:
Viruses, Vol 14, Iss 2, p 325 (2022)
SARS-CoV-2 can efficiently infect both children and adults, albeit with morbidity and mortality positively associated with increasing host age and presence of co-morbidities. SARS-CoV-2 continues to adapt to the human population, resulting in several
Externí odkaz:
https://doaj.org/article/7eb0dce777284585ab48e1334ebdc74c
Autor:
Fary Diop, Riccardo Moia, Chiara Favini, Elisa Spaccarotella, Lorenzo De Paoli, Alessio Bruscaggin, Valeria Spina, Lodovico Terzi-di-Bergamo, Francesca Arruga, Chiara Tarantelli, Clara Deambrogi, Silvia Rasi, Ramesh Adhinaveni, Andrea Patriarca, Simone Favini, Sruthi Sagiraju, Clive Jabangwe, Ahad A. Kodipad, Denise Peroni, Francesca R. Mauro, Ilaria Del Giudice, Francesco Forconi, Agostino Cortelezzi, Francesco Zaja, Riccardo Bomben, Francesca Maria Rossi, Carlo Visco, Annalisa Chiarenza, Gian Matteo Rigolin, Roberto Marasca, Marta Coscia, Omar Perbellini, Alessandra Tedeschi, Luca Laurenti, Marina Motta, David Donaldson, Phil Weir, Ken Mills, Patrick Thornton, Sarah Lawless, Francesco Bertoni, Giovanni Del Poeta, Antonio Cuneo, Antonia Follenzi, Valter Gattei, Renzo Luciano Boldorini, Mark Catherwood, Silvia Deaglio, Robin Foà, Gianluca Gaidano°, Davide Rossi°
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
BIRC3 is a recurrently mutated gene in chronic lymphocytic leukemia (CLL) but the functional implications of BIRC3 mutations are largely unexplored. Furthermore, little is known about the prognostic impact of BIRC3 mutations in CLL cohorts homogeneou
Externí odkaz:
https://doaj.org/article/a9268fbe11e941109905bc1ded8e6bf5
Publikováno v:
Breast Cancer Research, Vol 20, Iss 1, Pp 1-10 (2018)
Abstract Background Nearly 50% of breast cancer patients suffer from depression or anxiety. Selective serotonin reuptake inhibitors (SSRIs), the first-line pharmacological treatment for depression, have been implicated in breast cancer development th
Externí odkaz:
https://doaj.org/article/8e5f24e0995c42c491b03bac093d2fae
Autor:
Gayathri Thillaiyampalam, Fabio Liberante, Liam Murray, Chris Cardwell, Ken Mills, Shu-Dong Zhang
Publikováno v:
BMC Bioinformatics, Vol 18, Iss 1, Pp 1-16 (2017)
Abstract Background Gene expression connectivity mapping has gained much popularity in recent years with a number of successful applications in biomedical research testifying its utility and promise. A major application of connectivity mapping is the
Externí odkaz:
https://doaj.org/article/fcdd3dc5a1bf494b919fe4f39a6c8357
Autor:
Claire Lewis, Stephen McQuaid, Priscilla Clark, Paul Murray, Tracey McGuigan, Christine Greene, Bronagh Coulter, Ken Mills, Jacqueline James
Publikováno v:
Open Journal of Bioresources, Vol 5 (2018)
The Northern Ireland Biobank (NIB) was established in 2011 as a joint initiative between Queen’s University Belfast and Belfast Health and Social Care Trust to provide the infrastructure for the standardised collection and storage of high quality,
Externí odkaz:
https://doaj.org/article/50aab5a41e064e87abfd759c4357b634