Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ken Kwok-Keung Chan"'
Autor:
Hock Chuan Yeo, Thian Thian Beh, Jovina Jia Ling Quek, Geoffrey Koh, Ken Kwok Keung Chan, Dong-Yup Lee
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27231 (2011)
Rapid cellular growth and multiplication, limited replicative senescence, calibrated sensitivity to apoptosis, and a capacity to differentiate into almost any cell type are major properties that underline the self-renewal capabilities of human plurip
Externí odkaz:
https://doaj.org/article/80176bfd331747cdbe27f6e8c02fd493
Autor:
Huifang Shen, Ken Kwok Keung Chan, Si Wan Lei, Sharon Chui Wah Luk, Simon Ming-Yuen Lee, Liang Wang, Ronald A. Li, George P.H. Leung, Guozhen Cui
Publikováno v:
Journal of Cardiovascular Pharmacology. 65:39-46
Baicalein is one of the major flavonoids found in the rootof Scutellaria baicalensis Georgi. Previous studies suggest that bai-calein displays protective effect on experimental cardiac modelsin vitro and in vivo. However, the mode of action remains
Autor:
Andre Choo, Stanley Kwang-Loong Ng, Selena Meiyun Wu, Dong-Yup Lee, Thian Thian Beh, Shunhui Wei, Ker Sin Tan, Hock Chuan Yeo, Huishan Chen, Ken Kwok-Keung Chan
Publikováno v:
Stem Cells and Development. 21:729-741
Molecular and cellular signaling pathways are involved in the process of neural differentiation from human embryonic stem cells (hESC) to terminally differentiated neurons. The Sonic hedgehog (SHH) morphogen is required to direct the differentiation
Publikováno v:
Integrative Biology. 3:717-723
Human embryonic stem cells (hESC) are important to basic scientific research as an in vitro model system for the study of human development and to clinical research as an invaluable cell source for regenerative medicine. The ability to genetically en
Autor:
Na-Yu Chia, Andre Choo, Yun-Shen Chan, Hui Shan Sim, Jingyao Zhang, Ker Sin Tan, Steve Oh, Ken Kwok-Keung Chan, Huck-Hui Ng
Publikováno v:
Stem Cells. 27:2114-2125
Insight into the regulation of core transcription factors is important for a better understanding of the molecular mechanisms that control self-renewal and pluripotency of human ESCs (hESCs). However, the transcriptional regulation of NANOG itself in
Publikováno v:
Stem Cells and Development. 17:825-836
The utilization of human embryonic stem cells (hESC) in regenerative medicine largely depends on the development of technologies that will allow efficient genetic manipulation of the cells in vitro. Although a few studies have described the transfect
Autor:
Andre Choo, Charlene Li Ling Yong, Evert Klaseboer, Lisa Li Mei Heng, Tandiono Tandiono, Siew-Wan Ohl, Claus-Dieter Ohl, Dave Siak-Wei Ow, Ken Kwok-Keung Chan
Publikováno v:
Biotechnology journal. 9(8)
Sonoporation has not been widely explored as a strategy for the transfection of heterologous genes into notoriously difficult-to-transfect mammalian cell lines such as B cells. This technology utilizes ultrasound to create transient pores in the cell
Publikováno v:
Stem Cell Research
Stem Cell Research, Elsevier, 2013, 11 (2), pp.926-937. ⟨10.1016/j.scr.2013.06.004⟩
Stem Cell Research, Elsevier, 2013, 11 (2), pp.926-937. ⟨10.1016/j.scr.2013.06.004⟩
O-linked-N-acetylglucosamine (O-GlcNAc), a post translational modification, has emerged as an important cue in controlling key cell mechanisms. Here, we investigate O-GlcNAc's role in the maintenance and differentiation of human pluripotent stem cell
Publikováno v:
Stem cell research. 4(1)
Human embryonic stem cells (hESC) are characterized by their ability to self-renew and differentiate into all cell types of the body, making them a valuable resource for regenerative medicine. Yet, the molecular mechanisms by which hESC retain their
Autor:
Guozhen Cui, Sharon Chui Wah Luk, Adolphus Li, Ronald, Ken Kwok Keung Chan, Si Wan Lei, Liang Wang, Huifang Shen, George Pak Heng Leung, Simon Ming Yuen Lee
Publikováno v:
Journal of Cardiovascular Pharmacology; Jan2015, Vol. 65 Issue 1, p39-46, 8p