Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Ken Kin-lam Yung"'
Autor:
Zhu Zhang, Wen-Qing Chen, Shi-Qing Zhang, Jing-Xuan Bai, Ching-Lam Lau, Stephen Cho-Wing Sze, Ken Kin-Lam Yung, Joshua Ka-Shun Ko
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could be associated with promotion of autophagy and the tumor immune microenvironment. Studies have confirmed the pro-tumorigenic nature of the cathelicidin family of
Externí odkaz:
https://doaj.org/article/76ea504c5e1a4d11920d520ab3a55c07
Autor:
Kaili Lin, Stephen Cho-Wing Sze, Bin Liu, Zhang Zhang, Zhu Zhang, Peili Zhu, Ying Wang, Qiudi Deng, Ken Kin-Lam Yung, Shiqing Zhang
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 2, Pp 325-333 (2021)
Background: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 2
Externí odkaz:
https://doaj.org/article/89d76940d68748fc94c7c57ad9e61b4f
Autor:
Zhu Zhang, Shiqing Zhang, Cathy Nga-Ping Lui, Peili Zhu, Zhang Zhang, Kaili Lin, Yiwu Dai, Ken Kin-Lam Yung
Publikováno v:
Journal of Neurorestoratology, Vol 7, Iss 4, Pp 207-222 (2019)
The prevalence of multiple neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), has been dramatically increasing, particularly in the aging population. However, the currently available therapies merely allevi
Externí odkaz:
https://doaj.org/article/782e3caba1424b69ba5b38b22184b177
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1349 (2022)
Oxidative stress could lead to a variety of body dysfunctions, including neurodegeneration and cancer, which are closely associated with intracellular signal transducers such as reactive oxygen species (ROS). It has been suggested that ROS is the ups
Externí odkaz:
https://doaj.org/article/a0dd10d4a7ee4b8fb95e391b2ba6366a
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 12, p 6567 (2021)
The transmembrane glycoprotein mucin 1 (MUC1) is a mucin family member that has different functions in normal and cancer cells. Owing to its structural and biochemical properties, MUC1 can act as a lubricant, moisturizer, and physical barrier in norm
Externí odkaz:
https://doaj.org/article/9979707a8e5b4322806b4f14714cba63
Autor:
Zhu Zhang, Shiqing Zhang, Pengfei Fu, Zhang Zhang, Kaili Lin, Joshua Ka-Shun Ko, Ken Kin-Lam Yung
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 18, p 4391 (2019)
Parkinson’s disease is a progressive neurodegenerative disorder resulting from the degeneration of pigmented dopaminergic neurons in the substantia nigra pars compacta. It induces a series of functional modifications in the circuitry of the basal g
Externí odkaz:
https://doaj.org/article/0e10138d7ad74de3b81e980dd5b0c727
Autor:
Jinying Ou, Yuting Zhou, Chan Li, Zhijie Chen, Hancheng Li, Miao Fang, Chen Zhu, Chuying Huo, Ken Kin-Lam Yung, Jing Li, Chaohua Luo, Zhixian Mo
Publikováno v:
Molecules, Vol 23, Iss 9, p 2370 (2018)
Sinomenine is a nonaddictive alkaloid used to prevent morphine dependence, even thoughits mechanism isnot fully understood. Astrocytes aggravate the pathological process in their neighboring cellsthrough exosomes in central nervous system diseases. H
Externí odkaz:
https://doaj.org/article/0e8da6da4baa417d8a7d99580d318b38
Autor:
Siu Wai Tsang, Hongjie Zhang, Chengyuan Lin, Haitao Xiao, Michael Wong, Hongcai Shang, Zhi-Jun Yang, Aiping Lu, Ken Kin-Lam Yung, Zhaoxiang Bian
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82201 (2013)
Pancreatic fibrosis, a prominent histopathological feature of chronic pancreatitis (CP) and pancreatic ductal adenocarcinoma, is essentially a dynamic process that leads to irreversible scarring of parenchymal tissues of the pancreas. Though the exac
Externí odkaz:
https://doaj.org/article/964f382e74564d00a6a1d1b88cab2e64
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e51294 (2012)
Here we report a previously unknown self repair mechanism during extremely early stages of rat Parkinsonism. Two important cell survival signaling cascades, Phosphatidylinositol-3 kinases (PI3K)/Akt pathway and extracellular signal-regulated kinase/m
Externí odkaz:
https://doaj.org/article/5cd46ad201f44cffaea46de8842b8032
Autor:
Guang-Hui Deng, Chao-Feng Wu, Yun-Jia Li, Hao Shi, Wei-Chao Zhong, Mu-Keng Hong, Jun-Jie Li, Jia-Min Zhao, Chang Liu, Meng-Chen Qin, Zhi-Yun Zeng, Wei-Min Zhang, Ken Kin Lam Yung, Zhi-Ping Lv, Lei Gao
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-22 (2023)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is associated with disordered lipid and iron metabolism. Our previous study has substantiated the pivotal role of Caveolin-1 (Cav-1) in protecting hepatocytes and mediating iron metabolism
Externí odkaz:
https://doaj.org/article/7a3fad7a392347a9900d7b80d213c803