Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Ken Kin Lam, Yung"'
Autor:
Guang-Hui Deng, Chao-Feng Wu, Yun-Jia Li, Hao Shi, Wei-Chao Zhong, Mu-Keng Hong, Jun-Jie Li, Jia-Min Zhao, Chang Liu, Meng-Chen Qin, Zhi-Yun Zeng, Wei-Min Zhang, Ken Kin Lam Yung, Zhi-Ping Lv, Lei Gao
Publikováno v:
Military Medical Research, Vol 10, Iss 1, Pp 1-22 (2023)
Abstract Background Nonalcoholic fatty liver disease (NAFLD) is associated with disordered lipid and iron metabolism. Our previous study has substantiated the pivotal role of Caveolin-1 (Cav-1) in protecting hepatocytes and mediating iron metabolism
Externí odkaz:
https://doaj.org/article/7a3fad7a392347a9900d7b80d213c803
Autor:
Xiaoyan Wu, Xin Yi, Boxin Zhao, Yuanxing Zhi, Ziwei Xu, Ying Cao, Xiong Cao, Jianxin Pang, Ken Kin Lam Yung, Shiqing Zhang, Shuwen Liu, Pingzheng Zhou
Publikováno v:
Pharmacological Research, Vol 198, Iss , Pp 107016- (2023)
The NLRP3 inflammasome is a supramolecular complex that is linked to sterile and pathogen-dependent inflammation, and its excessive activation underlies many diseases. Ion flux disturbance and cell volume regulation are both reported to mediate NLRP3
Externí odkaz:
https://doaj.org/article/d8d493bd9e1d4acd8d32e06aaa0de23a
Autor:
Ka Man Yip, Kwan Ming Lee, Tzi Bun Ng, Shujun Xu, Ken Kin Lam Yung, Shaogang Qu, Allen Ka Loon Cheung, Stephen Cho Wing Sze
Publikováno v:
Chinese Medicine, Vol 17, Iss 1, Pp 1-20 (2022)
Abstract Background Since the outbreak of COVID-19 has resulted in over 313,000,000 confirmed cases of infection and over 5,500,000 deaths, substantial research work has been conducted to discover agents/ vaccines against COVID-19. Undesired adverse
Externí odkaz:
https://doaj.org/article/7ea8a37b54314cf1aa8e4f129b292a44
Publikováno v:
Journal of Environmental Sciences. 138:288-300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1db2c05d3baac8c14aca1507dd45427
https://doi.org/10.1016/j.jes.2023.03.016
https://doi.org/10.1016/j.jes.2023.03.016
Autor:
Zhu Zhang, Wen-Qing Chen, Shi-Qing Zhang, Jing-Xuan Bai, Ching-Lam Lau, Stephen Cho-Wing Sze, Ken Kin-Lam Yung, Joshua Ka-Shun Ko
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Pancreatic cancer is amongst the most lethal malignancies, while its poor prognosis could be associated with promotion of autophagy and the tumor immune microenvironment. Studies have confirmed the pro-tumorigenic nature of the cathelicidin family of
Externí odkaz:
https://doaj.org/article/76ea504c5e1a4d11920d520ab3a55c07
Autor:
Kaili Lin, Stephen Cho-Wing Sze, Bin Liu, Zhang Zhang, Zhu Zhang, Peili Zhu, Ying Wang, Qiudi Deng, Ken Kin-Lam Yung, Shiqing Zhang
Publikováno v:
Journal of Ginseng Research, Vol 45, Iss 2, Pp 325-333 (2021)
Background: Alzheimer's disease (AD) is one of the most prevalent neurodegenerative disorders. Enhancing hippocampal neurogenesis by promoting proliferation and differentiation of neural stem cells (NSCs) is a promising therapeutic strategy for AD. 2
Externí odkaz:
https://doaj.org/article/89d76940d68748fc94c7c57ad9e61b4f
Autor:
Junkui Li, Peili Zhu, Yifei Chen, Shiqing Zhang, Zhu Zhang, Zhang Zhang, Ying Wang, Xiaoli Jiang, Kaili Lin, Wei Wu, Zhixian Mo, Stephen Cho Wing Sze, Ken Kin Lam Yung
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Colorectal cancer (CRC) is an aggressive cancer. Isoalantolactone (IATL) has been reported to exert cytotoxicity against various cancer cells, but not CRC. In this study, we explored the anti-CRC effects and mechanism of action of IATL in vitro and i
Externí odkaz:
https://doaj.org/article/d9f5cb620b424cb28c9cd1eac38d1a26
Autor:
Zhu Zhang, Shiqing Zhang, Cathy Nga-Ping Lui, Peili Zhu, Zhang Zhang, Kaili Lin, Yiwu Dai, Ken Kin-Lam Yung
Publikováno v:
Journal of Neurorestoratology, Vol 7, Iss 4, Pp 207-222 (2019)
The prevalence of multiple neurodegenerative diseases, such as Alzheimer’s disease (AD) and Parkinson’s disease (PD), has been dramatically increasing, particularly in the aging population. However, the currently available therapies merely allevi
Externí odkaz:
https://doaj.org/article/782e3caba1424b69ba5b38b22184b177
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1457 (2022)
Japanese Ardisia is widely used as a hepatoprotective and anti-inflammatory agent in China. However, the active ingredients in Japanese Ardisia and their potential mechanisms of action in the treatment of autoimmune hepatitis (AIH) are unknown. The p
Externí odkaz:
https://doaj.org/article/ec43a57f71cf490ea65aefa0b445b334
Autor:
Stephen Cho Wing Sze, Liang Zhang, Shiqing Zhang, Kaili Lin, Tzi Bun Ng, Man Ling Ng, Kai-Fai Lee, Jenny Ka Wing Lam, Zhang Zhang, Ken Kin Lam Yung
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12689 (2022)
We report herein a novel mechanism, unraveled by proteomics and validated by in vitro and in vivo studies, of the aberrant aging-associated upregulation of ovarian transferrin and ferritin in rat ovaries. The ovarian mass and serum estradiol titer pl
Externí odkaz:
https://doaj.org/article/798cde20af354469a1cc3598765e97c3