Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Ken Ishiyama"'
Autor:
Hiroki Mizumaki, Dung Cao Tran, Kohei Hosokawa, Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Hiroyuki Takamatsu, Hirohito Yamazaki, Ken Ishiyama, Rena Yamazaki, Hiroshi Fujiwara, Atsushi Tajima, Shinji Nakao
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-5 (2023)
Externí odkaz:
https://doaj.org/article/bfc30ef69375475eaaebde07df5ae121
Autor:
Tatsuya Imi, Hiroki Mizumaki, Kazuyoshi Hosomichi, Yasuhito Nannya, Yoshitaka Zaimoku, Takeshi Yoroidaka, Takamasa Katagiri, Ken Ishiyama, Hirohito Yamazaki, Ryosuke Ogawa, Mika Kuroiwa, Atsushi Tajima, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 4, Iss 3, Pp 714-718 (2023)
Abstract We studied the pathophysiology of aplastic anaemia (AA) in six different pairs of relatives without a family history of hematologic disorders or congenital AA. Five and four of the six pairs shared the HLA‐DRB1*15:01 and B*40:02 alleles, r
Externí odkaz:
https://doaj.org/article/7e00c78c4c74405dae8a50cc6975fa8e
Autor:
Hiroki Mizumaki, Ken Ishiyama, Jun Aoki, Jinichi Mori, Shohei Mizuno, Noriko Doki, Takahiro Fukuda, Naoyuki Uchida, Masahito Onizuka, Masatsugu Tanaka, Yuta Katayama, Yukiyasu Ozawa, Kazuhiro Ikegame, Satoru Takada, Toshiro Kawakita, Nobuyuki Aotsuka, Yoshiko Atsuta, Masamitsu Yanada
Publikováno v:
eJHaem, Vol 4, Iss 1, Pp 251-257 (2023)
Abstract The prognosis of acute myeloid leukemia (AML) patients with der(1;7)(q10;p10) who underwent allogeneic hematopoietic stem cell transplantation (allo‐SCT) is unclear due to its rarity. We retrospectively analyzed 151 AML patients with der(1
Externí odkaz:
https://doaj.org/article/f8c29b89765d4b6d9344c3c0455cf547
Autor:
Ken Ishiyama, Tran Cao Dung, Tatsuya Imi, Kohei Hosokawa, Yasuhito Nannya, Hirohito Yamazaki, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1116-1125 (2022)
Abstract To determine the significance of increased Wilms tumor 1 (WT1) gene expression in the peripheral blood of patients with acquired aplastic anemia (AA), we analyzed serial changes in WT1 mRNA copy number (WT1cn) in 63 patients with AA as well
Externí odkaz:
https://doaj.org/article/a915a945bd9145b8a3dae8ec5dec4271
Autor:
Takamasa Katagiri, Jorge Luis Espinoza, Mizuho Uemori, Honoka Ikeda, Kohei Hosokawa, Ken Ishiyama, Takeshi Yoroidaka, Tatsuya Imi, Hiroyuki Takamatsu, Tatsuhiko Ozawa, Hiroyuki Kishi, Yasuhiko Yamamoto, Mahmoud Ibrahim Elbadry, Yoshinori Yoshida, Kazuhisa Chonabayashi, Katsuto Takenaka, Koichi Akashi, Yasuhito Nannya, Seishi Ogawa, Shinji Nakao
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 669-680 (2022)
Abstract The phenotypic changes in hematopoietic stem progenitor cells (HSPCs) with somatic mutations of malignancy‐related genes in patients with acquired aplastic anemia (AA) are poorly understood. As our initial study showed increased CXCR4 expr
Externí odkaz:
https://doaj.org/article/d29be8cd58114bf5b769d39c97fb15bd
Autor:
Ken Ishiyama, Keijiro Sato, Tatsuya Imi, Kohei Hosokawa, Yukio Kondo, Naomi Sugimori, Hirohito Yamazaki, Shinji Nakao
Publikováno v:
eJHaem, Vol 1, Iss 1, Pp 243-248 (2020)
Abstract To identify factors affecting responsiveness to eltrombopag (EPAG), we retrospectively analyzed 38 aplastic anemia patients treated with EPAG who were refractory (n = 29) or showed an inadequate response (n = 9) to conventional therapies. Th
Externí odkaz:
https://doaj.org/article/21264fb7ea7a49a2a41153669908a303
Autor:
Takayuki Inoue, Motoko Koyama, Katsuji Kaida, Kazuhiro Ikegame, Kathleen S. Ensbey, Luke Samson, Shuichiro Takahashi, Ping Zhang, Simone A. Minnie, Satoshi Maruyama, Shinichi Ishii, Takashi Daimon, Takahiro Fukuda, Hirohisa Nakamae, Takahide Ara, Yumiko Maruyama, Ken Ishiyama, Tatsuo Ichinohe, Yoshiko Atsuta, Bruce R. Blazar, Scott N. Furlan, Hiroyasu Ogawa, Geoffrey R. Hill
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
Patients with acute leukemia who are unable to achieve complete remission prior to allogeneic hematopoietic stem cell transplantation (SCT) have dismal outcomes, with relapse rates well in excess of 60%. Haplo-identical SCT (haplo-SCT) may allow enha
Externí odkaz:
https://doaj.org/article/97b29e5bedf04c2183e944ba8e74b318
Autor:
Yasuyuki Arai, Tadakazu Kondo, Hirohito Yamazaki, Katsuto Takenaka, Junichi Sugita, Takeshi Kobayashi, Yukiyasu Ozawa, Naoyuki Uchida, Koji Iwato, Naoki Kobayashi, Yoshiyuki Takahashi, Ken Ishiyama, Takahiro Fukuda, Tatsuo Ichinohe, Yoshiko Atsuta, Takehiko Mori, Takanori Teshima
Publikováno v:
Haematologica, Vol 101, Iss 5 (2016)
Allogeneic bone marrow transplantation is an essential therapy for acquired aplastic anemia and prognosis has recently improved. However, engraftment failure and graft-versus-host disease are potential fatal complications. Various risk factors for po
Externí odkaz:
https://doaj.org/article/3d7695928760410786cd30a4546828b9
Autor:
Kohei Hosokawa, Takamasa Katagiri, Naomi Sugimori, Ken Ishiyama, Yumi Sasaki, Yu Seiki, Aiko Sato-Otsubo, Masashi Sanada, Seishi Ogawa, Shinji Nakao
Publikováno v:
Haematologica, Vol 97, Iss 12 (2012)
To characterize bone marrow failure with del(13q), we reviewed clinical records of 22 bone marrow failure patients possessing del(13q) alone or del(13q) plus other abnormalities. All del(13q) patients were diagnosed with myelodysplastic syndrome-uncl
Externí odkaz:
https://doaj.org/article/dd901f4df73342ac9c2cb0d29d706f84
Autor:
Hidehiro Itonaga, Yasushi Miyazaki, Kazunari Aoki, Naoki Shingai, Yukiyasu Ozawa, Takahiro Fukuda, Keisuke Kataoka, Toshiro Kawakita, Yasunori Ueda, Takahide Ara, Masatsugu Tanaka, Yuta Katayama, Masashi Sawa, Tetsuya Eto, Junya Kanda, Yoshiko Atsuta, Ken Ishiyama
Publikováno v:
Annals of Hematology. 102:1215-1227