PLRP2 selectively localizes synaptic membrane proteins via acyl-chain remodeling of phospholipids

Autor: Ken-ichi Yagyu, Hideaki Kuge, Koichi Honke, Izumi Miyamoto

Publikováno v: Journal of Lipid Research, Vol 61, Iss 12, Pp 1747-1763 (2020)
J Lipid Res

The plasma membrane of neurons consists of distinct domains, each of which carries specialized functions and a characteristic set of membrane proteins. While this compartmentalized membrane organization is essential for neuronal functions, it remains

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cc048f0924ea0e1b7a9a21cfa769f01
https://doi.org/10.1194/jlr.ra120001087

High expression of nuclear factor 90 (NF90) leads to mitochondrial degradation in skeletal and cardiac muscles.

Autor: Takuma Higuchi, Shuji Sakamoto, Yoshihiko Kakinuma, Shoko Kai, Ken-Ichi Yagyu, Hiroshi Todaka, Eunsup Chi, Shoshiro Okada, Takako Ujihara, Keiko Morisawa, Masafumi Ono, Yasunori Sugiyama, Waka Ishida, Atsuki Fukushima, Masayuki Tsuda, Yasutoshi Agata, Taketoshi Taniguchi

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43340 (2012)

While NF90 has been known to participate in transcription, translation and microRNA biogenesis, physiological functions of this protein still remain unclear. To uncover this, we generated transgenic (Tg) mice using NF90 cDNA under the control of β-a

Externí odkaz: https://doaj.org/article/c5f5758e301a4348b577a74f9c35a9a2

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly

Autor: Shinya Ohta, Tatsuo Fukagawa, William C. Earnshaw, Ken Ichi Yagyu, Laura Wood, Iyo Toramoto

Publikováno v: Molecular Biology of the Cell
Ohta, S, Wood, L, Toramoto, I, Yagyu, K I, Fukagawa, T & Earnshaw, W C 2015, ' CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly ', Molecular Biology of the Cell, vol. 26, no. 7, pp. 1225-1237 . https://doi.org/10.1091/mbc.E14-09-1366

CENP-32 depletion releases centrosomes from spindles after initiating spindle assembly. The free centrosomes do not interfere with the structure or function of the bipolar anastral spindle. The asters appear to be able to interact with the surface of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15c53560ef3980293f6ae79d342eb2db
https://doi.org/10.1091/mbc.e14-09-1366

Rationale for Determining the Functional Potency of Mesenchymal Stem Cells in Preventing Regulated Cell Death for Therapeutic Use

Autor: Ken-ichi Yagyu, Frédéric Deschaseaux, Abderrahim Naji, Narufumi Suganuma, Nicolas Espagnolle, Luc Sensebé, Nobuyasu Baba

Publikováno v: Stem Cells Translational Medicine

Summary Mesenchymal stem (stromal) cells (MSCs) are being investigated for treating degenerative and inflammatory disorders because of their reparative and immunomodulatory properties. Intricate mechanisms relate cell death processes with immune resp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd4e520b5d1cfcc213bb48469eb1101
https://pubmed.ncbi.nlm.nih.gov/28297565

Histological and clinical study of eyes with true exfoliation and a double-ring sign on the anterior lens capsule

Autor: Toshiaki Nakakuki, Shigeru Kishi, Koji Nishino, Yumiko Yamamoto, Ken-ichi Yagyu, Hisayuki Ueno, Atsuki Fukushima

Publikováno v: Canadian Journal of Ophthalmology. 44:657-662

Objective: To investigate the histological and clinical relation between eyes with true exfoliation (TEX) and a double-ring sign (DRS). Study Design: Retrospective clinical case study. Participants: Twenty-four eyes of 22 patients who underwent catar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::120ad0f5c0ca1c50c957fb97c631435f
https://doi.org/10.3129/i09-162