Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Ken I. Welsh"'
Autor:
Peter J. Morris, Vincenzo Cerundolo, Margaret J. Dallman, Ken I. Welsh, Neil Thomas Young, Nigel A. Rust
Human NK cells express receptors (KIR) which inhibit lysis through binding to HLA class I on target cells. KIR expression in different individuals has not been intensively investigated and it is not known how the KIR repertoire relates to HLA type or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6cebf62fe5a343ea0a7fa0da756e30
https://ora.ox.ac.uk/objects/uuid:c117bd3b-ea85-42fd-bd97-cd1b915fcd94
https://ora.ox.ac.uk/objects/uuid:c117bd3b-ea85-42fd-bd97-cd1b915fcd94
Autor:
D.C. Jones, Peter J. Friend, Peter J. Morris, Sara E. Marshall, Margarete A. Fabre, Michael Bunce, Ken I. Welsh
Azathioprine metabolism is influenced by activity of the enzyme thiopurine S-methyltransferase (TPMT), which varies markedly between individuals. In this study we examined the influence of TPMT gene polymorphisms on azathioprine dose 1 year after ren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0001ee511b36f0f58026d721044e86a3
https://ora.ox.ac.uk/objects/uuid:f14b3732-6fbc-4db4-b767-8f78b0464858
https://ora.ox.ac.uk/objects/uuid:f14b3732-6fbc-4db4-b767-8f78b0464858
Autor:
Jane Setterfield, Martin M. Black, Stephen Challacombe, J. Theron, Robert Vaughan, Ken I. Welsh, Fenella Wojnarowska, E Mallon
BACKGROUND: Class I human leucocyte antigens (HLA) -A, -B, -Cw and class II HLA-DRB1, -DQB1 alleles were determined in 131 British Caucasian patients with mucous membrane pemphigoid (MMP) using serological and DNA-based methods. OBJECTIVES: To analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6015effb9e6ff0f5d0b43193b69008c8
https://ora.ox.ac.uk/objects/uuid:d3be5a6e-ef6d-465b-8968-ccc09acc753c
https://ora.ox.ac.uk/objects/uuid:d3be5a6e-ef6d-465b-8968-ccc09acc753c
Autor:
Cristina Bordea, Peter J. Morris, Charles G. Mullighan, Ken I. Welsh, Fenella Wojnarowska, Neil A. Haldar, Sara E. Marshall
Glutathione S-transferase polymorphisms and skin cancer after renal transplantation. Background Susceptibility to skin cancer after transplantation is multifactorial, and risk factors include skin type, sun exposure, and level of immunosuppression. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f6f6a314eec8c8b28a802f46e9e8b40
https://doi.org/10.1111/j.1523-1755.2000.00392.x
https://doi.org/10.1111/j.1523-1755.2000.00392.x
The contribution of human leucocyte antigen complex genes to disease phenotype in ulcerative colitis
Autor:
Tariq Ahmad, Alessandro Armuzzi, Michael Bunce, Ken I. Welsh, Matt J. Neville, Sara E. Marshall, Khoon-Lin Ling, Derek P. Jewell
Linkage and association studies implicate the human leucocyte antigen (HLA) region in genetic susceptibility to ulcerative colitis (UC). However, associations with specific variants have been inconsistent, even within defined ethnic groups. A genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7118a707b00c2e5cb65546debd2785e7
https://doi.org/10.1046/j.1399-0039.2003.00129.x
https://doi.org/10.1046/j.1399-0039.2003.00129.x
Autor:
Hiroe Sato, Matt Neville, Jonathan Crawshaw, Sue Goldthorpe, Khoon-Lin Ling, Derek P. Jewell, K. Mulcahy-Hawes, Michael Bunce, Ken I. Welsh, Sara E. Marshall, Martin Barnardo, Tariq Ahmad, Alessandro Armuzzi, Robert Walton
Detailed knowledge of linkage disequilibrium (LD) is regarded as a prerequisite for population-based disease gene mapping. Variable patterns across the human genome are now recognized, both between regions and populations. Here, we demonstrate that L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a54baff8c7bf70033d669a7210346591
https://ora.ox.ac.uk/objects/uuid:1b0d4596-3fdd-4abf-9323-c32ca80364b7
https://ora.ox.ac.uk/objects/uuid:1b0d4596-3fdd-4abf-9323-c32ca80364b7
Publikováno v:
Annals of the Rheumatic Diseases. 65:488-494
To conduct a case-control study to investigate whether there are independent tumour necrosis factor alpha (TNFalpha) or lymphotoxin alpha (LTalpha) haplotype associations with SLE or with any of the major serological subsets of SLE.157 patients with
Autor:
Mary Gulumian, Paul Wordsworth, Sara E. Marshall, Neil A. Haldar, Mohammed Tikly, Ken I. Welsh
Publikováno v:
Free Radical Biology and Medicine. 36:1403-1407
We performed a case-control study of polymorphisms of glutathione S-transferase (GST) isoenzymes and manganese superoxide dismutase (MnSOD) in black South Africans with systemic sclerosis (SSc). The frequency of the GSTM1*B phenotype was significantl
Autor:
Sara E. Marshall, Matt Neville, Robert Walton, Tariq Ahmad, Alessandro Armuzzi, K. Mulcahy-Hawes, Graham R. Wallace, Teifi James, Farida Fortune, Michael Bunce, Ken I. Welsh, Miles Stanford, Jonathan Crawshaw, Derek P. Jewell
Publikováno v:
Arthritis & Rheumatism. 48:807-813
Objective. Experimental evidence suggests that inappropriate regulation of tumor necrosis factor α (TNFα) may play a role in the pathogenesis of Behcet's disease (BD). This is supported by recent reports high-lighting the efficacy of anti-TNFα age
Autor:
Bruce Neri, Kirk J. Hogan, Ken I. Welsh, Rebecca R. Selzer, Matt J. Neville, Monika de Arruda, Megan Maguire, Brian Aizenstein, Robert Walton
Publikováno v:
BioTechniques. 32:S34-S43
The cytochrome p450 (CYP) superfamily comprises enzymes that play an essential role in the transformation of medically relevant compounds. Accurate genotyping of polymorphisms in members of this family is drawing increasing interest because certain a