Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ken Hull"'
Autor:
Hengjie Yuan, Katie L Houck, Ye Tian, Uddalak Bharadwaj, Ken Hull, Zhou Zhou, Mingzhao Zhu, Xiaoping Wu, David J Tweardy, Daniel Romo, Xiaoyun Fu, Yanjun Zhang, Jianning Zhang, Jing-fei Dong
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146626 (2016)
Externí odkaz:
https://doaj.org/article/89ee3a8f2f264c29b67927bf7264931b
Autor:
Hengjie Yuan, Katie L Houck, Ye Tian, Uddalak Bharadwaj, Ken Hull, Zhou Zhou, Mingzhao Zhu, Xiaoping Wu, David J Tweardy, Daniel Romo, Xiaoyun Fu, Yanjun Zhang, Jianning Zhang, Jing-fei Dong
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143964 (2015)
Piperlongumine (PL) is a compound isolated from the piper longum plant. It possesses anti-cancer activities through blocking the transcription factor STAT3 and by inducing reactive oxygen species (ROS) in cancer, but not normal cells. It also inhibit
Externí odkaz:
https://doaj.org/article/e45434beccad43059020abbbada75f83
Autor:
Jaleesia Amos, Benjamin C. Morse, Margaret E. Glasner, Mariana S. Lopez, Mingzhao Zhu, Andrew W. McMillan, Daniel Romo, In-Cheol Yeo, Ken Hull
Publikováno v:
Biochemistry. 53:4434-4444
The o-succinylbenzoate synthase (OSBS) family is part of the functionally diverse enolase superfamily. Many proteins in one branch of the OSBS family catalyze both OSBS and N-succinylamino acid racemization in the same active site. In some promiscuou
Autor:
Andrew W. McMillan, Margaret E. Glasner, Daniel Romo, Ashley M. Brizendine, Denis Odokonyero, Ken Hull, Mingzhao Zhu
Publikováno v:
Biochemical and Biophysical Research Communications. 450:679-684
Catalytic promiscuity, which is the ability to catalyze more than one reaction in the same active site, is thought to facilitate the evolution of new protein functions. Although many enzymes are catalytically promiscuous, there is little direct evide
Autor:
Janki Shah-Mittal, Daniel Romo, Ken Hull, Jing Li, Sai Shilpa Kommaraju, Mingzhao Zhu, Jun O. Liu, Woon-Kai Low
Publikováno v:
Bioorganic & Medicinal Chemistry. 22:116-125
A series of pateamine A (1) derivatives were synthesized for structure/activity relationship (SAR) studies and a selection of previous generation analogs were re-evaluated based on current information regarding the mechanism of action of these transl
Autor:
Kevin J. Embrey, Julie Demeritt, Joanna Bryant, Beth Andrews, George B. Mullen, Ning Gao, Lawrence Macpherson, James T. Loch, Ken Hull, Bryan Prince, Brian Sherer, Alok Singh, P. Ann Boriack-Sjodin, Sheila Irene Hauck, Oluyinka Green, Ann E. Eakin, Haihong Ni, Ruth Illingworth, Dave Timms, Maria Uria-Nickelsen, Grant K. Walkup, Neil James Hales, Alexander L. Breeze, April E. Blodgett, Shanta Bist
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:1240-1246
DNA gyrase is an essential enzyme in bacteria, and its inhibition results in the disruption of DNA synthesis and, subsequently, cell death. The pyrrolamides are a novel class of antibacterial agents targeting DNA gyrase. These compounds were identifi
Autor:
Dave Clarke, Ken Hull
Publikováno v:
British Journal of Nursing. 19:346-350
The aim of this discussion is to explore the issue’s procedural restraint of children raises for nursing staff caring for children, from both a policy and a research perspective. Specifically the discussion defines the various terms that describe t
Autor:
Pat Turton, Ken Hull
Publikováno v:
British journal of nursing (Mark Allen Publishing). 23(15)
The concept of the ‘key-worker role’ within paediatric haematology and oncology services is recognised in the UK through inclusion in published policies and guidance. Such guidance originates from both statutory and voluntary sector organisations
Autor:
Pamela Hill, Fei Zhou, Ann E. Eakin, Ken Hull, Brian Sherer, C. Edwin Garner, P. Brian Dangel, Oluyinka Green, Mike Rooney, John I. Manchester, Sheila Irene Hauck, Maria Uria-Nickelsen, Richard A. Alm, Gregory S. Basarab, Ruth Illingworth, Shanta Bist
Publikováno v:
Journal of medicinal chemistry. 57(14)
AZD5099 (compound 63) is an antibacterial agent that entered phase 1 clinical trials targeting infections caused by Gram-positive and fastidious Gram-negative bacteria. It was derived from previously reported pyrrolamide antibacterials and a fragment
Autor:
Ken, Hull, Dave, Clarke
Publikováno v:
British journal of nursing (Mark Allen Publishing). 19(6)
The aim of this discussion is to explore the issue's procedural restraint of children raises for nursing staff caring for children, from both a policy and a research perspective. Specifically the discussion defines the various terms that describe the