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LBP-20-VK2809, a Novel Liver-Directed Thyroid Receptor Beta Agonist, Significantly Reduces Liver Fat with Both Low and High Doses in Patients with Non-Alcoholic Fatty Liver Disease: A Phase 2 Randomized, Placebo-Controlled Trial

Autor: Joel Neutel, Hiroko Masamune, Marianne Mancini, Rizwana Mohseni, Brian Lian, Michael Dao, Rohit Loomba, Randall Severance, Carmen Margaritescu, Satinder Saini, David Bernard, Ken Homer, Brian Tran

Publikováno v: Journal of Hepatology. 70:e150-e151

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4d67b187f91d516908a87d2260ba5a4
https://doi.org/10.1016/s0618-8278(19)30266-x

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Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects

Autor: Joel Neutel, Ajit K. Shah, Jeffrey Thompson, Raj Khankari, Ken Homer, Ken Tempero

Publikováno v: The Journal of Clinical Pharmacology. 54:546-554

This was a double blind, randomized, crossover study of three periods evaluating pharmacokinetics and pharmacodynamics in 12 healthy, adult subjects after administration of D-ribose powder for oral solution, 2.5, 5.0, and 10.0 g, under fasting condit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6bdb0ce4b3e952a947ac922b6ace9521
https://doi.org/10.1002/jcph.241

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Finding the 'sweet spot' in value-based contracts

Autor: Bill, Eggbeer, Kevin, Sears, Ken, Homer

Publikováno v: Healthcare financial management : journal of the Healthcare Financial Management Association. 69(8)

Health systems pursing value-based contracts should address six important considerations: The definition of value. Contracting goals. Cost of implementation. Risk exposure. Contract structure and design. Essential contractual protections.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4041c27bf0dc82a6f4b5b52b684ee3ff
https://pubmed.ncbi.nlm.nih.gov/26548138

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Evaluation of D-ribose pharmacokinetics, dose proportionality, food effect, and pharmacodynamics after oral solution administration in healthy male and female subjects

Autor: Jeff, Thompson, Joel, Neutel, Ken, Homer, Ken, Tempero, Ajit, Shah, Raj, Khankari

Publikováno v: Journal of clinical pharmacology. 54(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f4459e8eeb845e69c23f67a32c5804fb
https://pubmed.ncbi.nlm.nih.gov/24272966

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