Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ken G. Andersson"'
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTRecent development of amyloid-β (Aβ)-targeted immunotherapies for Alzheimer’s disease (AD) have highlighted the need for accurate diagnostic methods. Antibody-based positron emission tomography (PET) ligands are well suited for this purpo
Externí odkaz:
https://doaj.org/article/e26e8d4cee664eda81a36e31dae1d509
Autor:
Tobias Gustavsson, Nicole G. Metzendorf, Elin Wik, Sahar Roshanbin, Ulrika Julku, Aikaterini Chourlia, Per Nilsson, Ken G. Andersson, Hanna Laudon, Greta Hultqvist, Stina Syvänen, Dag Sehlin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background Brain-directed immunotherapy is a promising strategy to target amyloid-β (Aβ) deposits in Alzheimer’s disease (AD). In the present study, we compared the therapeutic efficacy of the Aβ protofibril targeting antibody RmAb158 w
Externí odkaz:
https://doaj.org/article/e33e7887ceef437fa638b612c0f45d72
Autor:
Gillian Bonvicini, Stina Syvänen, Ken G. Andersson, Merja Haaparanta-Solin, Francisco López-Picón, Dag Sehlin
Publikováno v:
Translational Neurodegeneration, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Hijacking the transferrin receptor (TfR) is an effective strategy to transport amyloid-beta (Aβ) immuno-positron emission tomography (immunoPET) ligands across the blood–brain barrier (BBB). Such ligands are more sensitive and
Externí odkaz:
https://doaj.org/article/ac051588a8784bbeb94c18e3d8ad8f8d
Autor:
Javad Garousi, Ken G. Andersson, Johan H. Dam, Birgitte B. Olsen, Bogdan Mitran, Anna Orlova, Jos Buijs, Stefan Ståhl, John Löfblom, Helge Thisgaard, Vladimir Tolmachev
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Several anti-cancer therapies target the epidermal growth factor receptor (EGFR). Radionuclide imaging of EGFR expression in tumours may aid in selection of optimal cancer therapy. The 111In-labelled DOTA-conjugated ZEGFR:2377 Affibody molec
Externí odkaz:
https://doaj.org/article/8a636f58f2cd44c59a45fa82c0cdd9f2
Autor:
Maryam Oroujeni, Tianqi Xu, Katherine Gagnon, Sara S. Rinne, Jan Weis, Javad Garousi, Ken G. Andersson, John Löfblom, Anna Orlova, Vladimir Tolmachev
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 292 (2021)
Epidermal growth factor receptor (EGFR) is overexpressed in many malignancies. EGFR-targeted therapy extends survival of patients with disseminated cancers. Radionuclide molecular imaging of EGFR expression would make EGFR-directed treatment more per
Externí odkaz:
https://doaj.org/article/e37a7216bdee47a5933c4ad6900b8e94
Autor:
Maryam Oroujeni, Javad Garousi, Ken G. Andersson, John Löfblom, Bogdan Mitran, Anna Orlova, Vladimir Tolmachev
Publikováno v:
Cells, Vol 7, Iss 9, p 141 (2018)
Radionuclide imaging of epidermal growth factor receptor (EGFR) expression in tumors may stratify patients for EGFR-targeting therapies and predict response or resistance to certain treatments. Affibody molecules, which are nonimmunoglobulin scaffold
Externí odkaz:
https://doaj.org/article/972fa05cb25e4866a230fe1cb847ef9c
Autor:
Jan Weis, Tianqi Xu, Anna Orlova, Maryam Oroujeni, Sara S. Rinne, Javad Garousi, Ken G. Andersson, Katherine Gagnon, Vladimir Tolmachev, John Löfblom
Publikováno v:
Pharmaceutics, Vol 13, Iss 292, p 292 (2021)
Pharmaceutics
Volume 13
Issue 2
Pharmaceutics
Volume 13
Issue 2
Epidermal growth factor receptor (EGFR) is overexpressed in many malignancies. EGFR-targeted therapy extends survival of patients with disseminated cancers. Radionuclide molecular imaging of EGFR expression would make EGFR-directed treatment more per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026bbc53d81bcdfabb3039fe10a18c13
https://pubmed.ncbi.nlm.nih.gov/33672373
https://pubmed.ncbi.nlm.nih.gov/33672373
Autor:
Anders Virtanen, U. Helena Danielson, Mohammad Reza Housaindokht, Olle Nordesjö, Sara Marie Øie Solbak, Daniel F. A. R. Dourado, Ken G. Andersson, Mikael Nissbeck, John Löfblom, Samuel C. Flores, Masoumeh Nosrati
Publikováno v:
Protein Engineering, Design and Selection. 30:593-601
The interaction between the Staphylococcal Protein A (SpA) domain B (the basis of the Affibody) molecule and the Fc of IgG is key to the use of Affibodies in affinity chromatography and in potential therapies against certain inflammatory diseases. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c5aca5ad42c498a4412956f0022a50
https://doi.org/10.1093/protein/gzx023
https://doi.org/10.1093/protein/gzx023
Autor:
Bogdan Mitran, Vladimir Tolmachev, Sara S. Rinne, Ken G. Andersson, Charles Dahlsson Leitao, Anna Orlova, Stefan Ståhl, John Löfblom, Anzhelika Vorobyeva
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1080 (2019)
Volume 20
Issue 5
International Journal of Molecular Sciences, Vol 20, Iss 5, p 1080 (2019)
Volume 20
Issue 5
Affibody-based imaging of HER3 is a promising approach for patient stratification. We investigated the influence of a hydrophilic HEHEHE-tag ((HE)3-tag) and two different gallium-68/chelator-complexes on the biodistribution of Z08698 with the aim to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c862d1d5c737ff350a81b47fe80b36ab
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-381825
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-381825
Autor:
Bogdan Mitran, Ken G. Andersson, Javad Garousi, Sandra Heskamp, Fokko J. Huizing, Vladimir Tolmachev, John Löfblom, Fredrik Y. Frejd, Anna Orlova, Johan Bussink, Anzhelika Vorobyeva, Charles Dahlsson Leitao
Publikováno v:
Scientific Reports, 9
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Carbonic anhydrase IX (CAIX) is a cancer-associated molecular target for several classes of therapeutics. CAIX is overexpressed in a large fraction of renal cell carcinomas (RCC). Radionuclide molecular imaging of CAIX-expression might offer a non-in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5f0522dd0452f6d5b91925721161f12
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-396709
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-396709