Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Ken E Olson"'
Autor:
Michel Tassetto, Mark Kunitomi, Zachary J Whitfield, Patrick T Dolan, Irma Sánchez-Vargas, Miguel Garcia-Knight, Isabel Ribiero, Taotao Chen, Ken E Olson, Raul Andino
Publikováno v:
eLife, Vol 8 (2019)
Aedes aegypti transmit pathogenic arboviruses while the mosquito itself tolerates the infection. We examine a piRNA-based immunity that relies on the acquisition of viral derived cDNA (vDNA) and how this pathway discriminates between self and non-sel
Externí odkaz:
https://doaj.org/article/ea7842ae357541ff9c9984e3ebe0a05e
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 8, p e0006754 (2018)
Aedes aegypti is the primary mosquito vector of dengue viruses (DENV; serotypes 1-4). Human-mosquito transmission cycles maintain DENV during epidemics but questions remain regarding how these viruses survive when human infections and vector abundanc
Externí odkaz:
https://doaj.org/article/c6cec4ab9ca64ee7a292f365022b7916
Autor:
Alexander W E Franz, Irma Sanchez-Vargas, Robyn R Raban, William C Black, Anthony A James, Ken E Olson
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2833 (2014)
In 2006, we reported a mariner (Mos1)-transformed Aedes aegypti line, Carb77, which was highly resistant to dengue-2 virus (DENV2). Carb77 mosquitoes expressed a DENV2-specific inverted-repeat (IR) RNA in midgut epithelial cells after ingesting an in
Externí odkaz:
https://doaj.org/article/320652fc8a32429a96fc7e0bd936e147
Autor:
Aaron T Phillips, Charles B Stauft, Tawfik A Aboellail, Ann M Toth, Donald L Jarvis, Ann M Powers, Ken E Olson
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53462 (2013)
Western equine encephalitis virus (WEEV; Alphavirus) is a mosquito-borne virus that can cause severe encephalitis in humans and equids. Previous studies have shown that intranasal infection of outbred CD-1 mice with the WEEV McMillan (McM) strain res
Externí odkaz:
https://doaj.org/article/8eff5a9aa00547ff8d477e5b7fc01e70
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84930 (2013)
Current methods for detecting real-time alphavirus (Family Togaviridae) infection in mosquitoes require the use of recombinant viruses engineered to express a visibly detectable reporter protein. These altered viruses expressing fluorescent proteins,
Externí odkaz:
https://doaj.org/article/12fa2984f74740d5a572063dc86b8402
Autor:
Eric C Mossel, Jeremy P Ledermann, Aaron T Phillips, Erin M Borland, Ann M Powers, Ken E Olson
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e60427 (2013)
Western equine encephalitis virus (WEEV) is a naturally occurring recombinant virus derived from ancestral Sindbis and Eastern equine encephalitis viruses. We previously showed that infection by WEEV isolates McMillan (McM) and IMP-181 (IMP) results
Externí odkaz:
https://doaj.org/article/6f9f153294bd46329bed718cf916ae73
Autor:
Scott A Bernhardt, Mark P Simmons, Ken E Olson, Barry J Beaty, Carol D Blair, William C Black
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44198 (2012)
RNA silencing, or RNA interference (RNAi) in metazoans mediates development, reduces viral infection and limits transposon mobility. RNA silencing involves 21-30 nucleotide RNAs classified into microRNA (miRNA), exogenous and endogenous small interfe
Externí odkaz:
https://doaj.org/article/8659ddf07e6f41829ae0c7e5b84046fb
Autor:
Mariangela Bonizzoni, W Augustine Dunn, Corey L Campbell, Ken E Olson, Osvaldo Marinotti, Anthony A James
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50512 (2012)
Dengue fever is the most important arboviral disease world-wide, with Aedes aegypti being the major vector. Interactions between the mosquito host and dengue viruses (DENV) are complex and vector competence varies among geographically-distinct Ae. ae
Externí odkaz:
https://doaj.org/article/ce088ce5705d47c2abeceeb0753ef5b1
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 6, Iss 11, p e1918 (2012)
Chikungunya is a mosquito-borne viral infection of humans that previously was confined to regions in central Africa. However, during this century, the virus has shown surprising potential for geographic expansion as it invaded other countries includi
Externí odkaz:
https://doaj.org/article/60464bc77f5a4f82b0069a463625f137
Autor:
Doug E Brackney, Jaclyn C Scott, Fumihiko Sagawa, Jimmy E Woodward, Neil A Miller, Faye D Schilkey, Joann Mudge, Jeffrey Wilusz, Ken E Olson, Carol D Blair, Gregory D Ebel
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 10, p e856 (2010)
Mosquitoes rely on RNA interference (RNAi) as their primary defense against viral infections. To this end, the combination of RNAi and invertebrate cell culture systems has become an invaluable tool in studying virus-vector interactions. Nevertheless
Externí odkaz:
https://doaj.org/article/9148a471460d481b8aa476f504b8eb70